Search Results - "Bone, Leslie N"

The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic by Bone, Leslie N, Dayam, Roya M, Lee, Minhyoung, Kono, Nozomu, Fairn, Gregory D, Arai, Hiroyuki, Botelho, Roberto J, Antonescu, Costin N

“…Phosphoinositides (PIPs) are key regulators of membrane traffic and signaling. The interconversion of PIPs by lipid kinases and phosphatases regulates their…”
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Selective regulation of clathrin-mediated epidermal growth factor receptor signaling and endocytosis by phospholipase C and calcium by Delos Santos, Ralph Christian, Bautista, Stephen, Lucarelli, Stefanie, Bone, Leslie N, Dayam, Roya M, Abousawan, John, Botelho, Roberto J, Antonescu, Costin N

“…Clathrin-mediated endocytosis is a major regulator of cell-surface protein internalization. Clathrin and other proteins assemble into small invaginating…”
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The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling by Chan, Victoria, Camardi, Cristina, Zhang, Kai, Orofiamma, Laura A, Anderson, Karen E, Hoque, Jafarul, Bone, Leslie N, Awadeh, Yasmin, Lee, Daniel K C, Fu, Norman J, Chow, Jonathan T S, Salmena, Leonardo, Stephens, Len R, Hawkins, Phillip T, Antonescu, Costin N, Botelho, Roberto J

“…Receptor tyrosine kinases such as EGF receptor (EGFR) stimulate phosphoinositide 3 kinases to convert phosphatidylinositol-4,5-bisphosophate [PtdIns(4,5)P ]…”
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Differential recruitment of E3 ubiquitin ligase complexes regulates RET isoform internalization by Hyndman, Brandy D, Crupi, Mathieu J F, Peng, Susan, Bone, Leslie N, Rekab, Aisha N, Lian, Eric Y, Wagner, Simona M, Antonescu, Costin N, Mulligan, Lois M

“…The RET receptor tyrosine kinase is implicated in normal development and cancer. RET is expressed as two isoforms, RET9 and RET51, with unique C-terminal tail…”
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Distinct Temporal Regulation of RET Isoform Internalization: Roles of Clathrin and AP2 by Crupi, Mathieu J. F., Yoganathan, Piriya, Bone, Leslie N., Lian, Eric, Fetz, Andrew, Antonescu, Costin N., Mulligan, Lois M.

“…The RET (REarranged during Transfection) receptor tyrosine kinase (RTK) is expressed as two major isoforms, each with important but distinct developmental…”
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The lipid acyltransferase LYCAT controls phosphatidylinositol‐3,4,5‐trisphosphate (PIP3) signaling by Antonescu, Costin N, Bone, Leslie N, Khuffash, Saba, Awadeh, Yasmin, Genc, Gizem E, Defferrari, Marina, Botelho, Roberto J

“…Phosphatidylinositol‐3,4,5‐trisphospate (PIP3) is a potent signaling lipid that exerts key control over cell growth, survival, adhesion and migration. PIP3…”
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Abstract 4986: Distinct temporal regulation of RET isoform internalization: Roles of clathrin and AP2 by Crupi, Mathieu Joseph François, Yoganathan, Piriya, Bone, Leslie N., Lian, Eric, Fetz, Andrew, Antonescu, Costin N., Mulligan, Lois M.

“…Abstract The RET receptor tyrosine kinase is an important contributor to kidney and enteric nervous system development. In normal development, RET signaling…”
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