Search Results - "Bonder, E M"
-
1
Rho-Dependent Formation of Epithelial "Leader" Cells during Wound Healing
Published in Proceedings of the National Academy of Sciences - PNAS (16-09-2003)“…The motile behavior of epithelial cells located at the edge of a large wound in a monolayer of cultured cells was analyzed. The initial cellular response is…”
Get full text
Journal Article -
2
Rho Overexpression Leads to Mitosis-Associated Detachment of Cells from Epithelial Sheets: A Link to the Mechanism of Cancer Dissemination
Published in Proceedings of the National Academy of Sciences - PNAS (24-08-2004)“…Dissemination of neoplastic cells from the primary tumor (invasion and metastasis) is a fundamentally dangerous step in multistage carcinogenesis. Recent…”
Get full text
Journal Article -
3
Mechanisms of Polarization of the Shape of Fibroblasts and Epitheliocytes: Separation of the Roles of Microtubules and Rho-Dependent Actin-Myosin Contractility
Published in Proceedings of the National Academy of Sciences - PNAS (06-08-2002)“…Cultured fibroblasts possess a characteristic polarized phenotype manifested by an elongate cell body with an anterior lamella whose cell edge is divided into…”
Get full text
Journal Article -
4
Contact Interactions between Epitheliocytes and Fibroblasts: Formation of Heterotypic Cadherin-Containing Adhesion Sites is Accompanied by Local Cytoskeletal Reorganization
Published in Proceedings of the National Academy of Sciences - PNAS (17-07-2001)“…Contact interactions between different cell types play a number of important roles in development, for example in cell sorting, tissue organization, and…”
Get full text
Journal Article -
5
Myosin-Dependent Contractile Activity of the Actin Cytoskeleton Modulates the Spatial Organization of Cell-Cell Contacts in Cultured Epitheliocytes
Published in Proceedings of the National Academy of Sciences - PNAS (17-08-1999)“…The spatial organization of cell-cell adherens junctions is distinct in cultured cells from two different tissue types, specifically, epitheliocytes and…”
Get full text
Journal Article -
6
Dynamics of Contacts between Lamellae of Fibroblasts: Essential Role of the Actin Cytoskeleton
Published in Proceedings of the National Academy of Sciences - PNAS (14-04-1998)“…We investigated actin cytoskeletal and adhesion molecule dynamics during collisions of leading lamellae of nontransformed and oncogene-transformed fibroblasts…”
Get full text
Journal Article -
7
Cell-Cell Contact Changes the Dynamics of Lamellar Activity in Nontransformed Epitheliocytes but not in their ras-Transformed Descendants
Published in Proceedings of the National Academy of Sciences - PNAS (04-02-1997)“…We investigated the structural and functional alterations of active lamellae during initial cell-cell collision and establishment of cell-cell contacts in…”
Get full text
Journal Article -
8
Analysis of Dynamin Isoforms in Mammalian Brain: Dynamin-1 Expression is Spatially and Temporally Regulated During Postnatal Development
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1992)“…In adult rat brain, the microtubule-associated protein dynamin is composed of a closely spaced polypeptide doublet of ≈100 kDa. Using an antibody preparation…”
Get full text
Journal Article -
9
A Calsequestrin-like Protein in the Endoplasmic Reticulum of the Sea Urchin: Localization and Dynamics in the Egg and First Cell Cycle Embryo
Published in The Journal of cell biology (01-07-1989)“…Using an antiserum produced against a purified calsequestrin-like (CSL) protein from a microsomal fraction of sea urchin eggs, we performed light and electron…”
Get full text
Journal Article -
10
Characterization of sea urchin unconventional myosins and analysis of their patterns of expression during early embryogenesis
Published in Molecular reproduction and development (01-10-2000)“…Early sea urchin development requires a dynamic reorganization of both the actin cytoskeleton and cytoskeletal interactions with cellular membranes. These…”
Get full text
Journal Article -
11
Cytochalasin B Slows but Does Not Prevent Monomer Addition at the Barbed End of the Actin Filament
Published in The Journal of cell biology (01-01-1986)“…We used Limulus sperm acrosomal actin bundles to examine the effect of 2 μM cytochalasin B (CB) on elongation from both the barbed and pointed ends of the…”
Get full text
Journal Article -
12
Actin from Thyone Sperm Assembles on Only One End of an Actin Filament: A Behavior Regulated by Profilin
Published in The Journal of cell biology (01-07-1983)“…Thyone sperm were demembranated with Triton X-100 and, after washing, extracted with 30 mM Tris at pH 8.0 and 1 mM MgCl2. After the insoluble contaminants were…”
Get full text
Journal Article -
13
Dynamics of Active Lamellae in Cultured Epithelial Cells: Effects of Expression of Exogenous N-ras Oncogene
Published in Proceedings of the National Academy of Sciences - PNAS (06-06-1995)“…We examined the functional consequences of cellular transformation of rat IAR-2 epithelial cells, by a mutant N-ras oncogene, on the dynamics of active…”
Get full text
Journal Article -
14
Identification of coelomocyte unconventional myosin and its association with in vivo particle/vesicle motility
Published in Journal of cell science (01-08-1994)“…Sea urchin coelomocytes undergo an inducible structural transformation from petalloid to filopodial form during the 'clotting' response in sea urchins. Using a…”
Get full text
Journal Article -
15
Sea Urchin Egg 100-kDa Dynamin-Related Protein: Identification of and Localization to Intracellular Vesicles
Published in Developmental biology (01-10-1993)“…We have initiated a study to identify possible tubulin dimer binding proteins from unfertilized sea urchin eggs utilizing tubulin dimer coupled to Sepharose…”
Get full text
Journal Article -
16
Reversible Structural Alterations of Undifferentiated and Differentiated Human Neuroblastoma Cells Induced by Phorbol Ester
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1992)“…Morphological alterations in the structure of undifferentiated and morphologically differentiated human neuroblastoma cells induced by phorbol 12-myristate…”
Get full text
Journal Article -
17
Actin-membrane cytoskeletal dynamics in early sea urchin development
Published in Current topics in developmental biology (1995)Get more information
Journal Article -
18
Subcellular localization of sea urchin egg spectrin: Evidence for assembly of the membrane-skeleton on unique classes of vesicles in eggs and embryos
Published in Developmental biology (01-12-1990)“…A recent study from our laboratory on the sea urchin egg suggested that spectrin was not solely restricted to the plasma membrane, but instead had a more…”
Get full text
Journal Article -
19
The cortical actin-membrane cytoskeleton of unfertilized sea urchin eggs: Analysis of the spatial organization and relationship of filamentous actin, nonfilamentous actin, and egg spectrin
Published in Developmental biology (01-08-1989)“…Whole mounts, cryosections, and isolated cortices of unfertilized sea urchin eggs were probed with fluorescent phalloidin, anti-actin and anti-egg spectrin…”
Get full text
Journal Article -
20
A novel vesicle-associated protein (VAP-1) in sea urchin eggs containing multiple RNA-binding consensus sequences
Published in Journal of cell science (01-11-1992)“…We have identified a novel high molecular weight, vesicle-associated protein (VAP-1) in the eggs of the sea urchin Strongylocentrotus purpuratus. Biochemical…”
Get full text
Journal Article