Search Results - "Bonder, CS"

Regulation of surface and soluble TNF receptor expression on human monocytes and synovial fluid macrophages by IL-4 and IL-10 by Hart, PH, Hunt, EK, Bonder, CS, Watson, CJ, Finlay-Jones, JJ

“…By regulating monocyte and macrophage production of IL-1, its receptor, and its receptor antagonist, IL-4 and IL-10 may exert significant anti-inflammatory…”
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Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs by Andonegui, Graciela, Bonder, Claudine S., Green, Francis, Mullaly, Sarah C., Zbytnuik, Lori, Raharjo, Eko, Kubes, Paul

“…The rapid and selective accumulation of neutrophils into the lungs is thought to underlie the pulmonary failure that leads to sepsis-related death. In this…”
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329 - A low-fouling polymer coating combined with key biomolecules as an endothelial cell selective platform for stents by Burzava, AL, Moore, E, Cockshell, MP, Harding, FJ, Bonder, CS, Voelcker, N

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A low-fouling polymer coating combined with key biomolecules as an endothelial cell selective platform for stents by Burzava, AL, Moore, E, Cockshell, MP, Harding, FJ, Bonder, CS, Voelcker, N

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Essential Role for Neutrophil Recruitment to the Liver in Concanavalin A-Induced Hepatitis by Bonder, Claudine S, Ajuebor, Maureen N, Zbytnuik, Lori D, Kubes, Paul, Swain, Mark G

“…Leukocyte infiltration into the liver is paramount to the development of liver injury in hepatitis. Hepatitis occurring after the administration of Con A in…”
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Rules of Recruitment for Th1 and Th2 Lymphocytes in Inflamed Liver: A Role for Alpha-4 Integrin and Vascular Adhesion Protein-1 by Bonder, Claudine S., Norman, M. Ursula, Swain, Mark G., Zbytnuik, Lori D., Yamanouchi, Jun, Santamaria, Pere, Ajuebor, Maureen, Salmi, Marko, Jalkanen, Sirpa, Kubes, Paul

“…The mechanisms that mediate the recruitment of Th1 and Th2 lymphocytes in vivo are poorly understood. We demonstrate that the mechanisms by which exogenously…”
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Use of CD44 by CD4+ Th1 and Th2 lymphocytes to roll and adhere by Bonder, Claudine S., Clark, Stephen R., Norman, M. Ursula, Johnson, Pauline, Kubes, Paul

“…Localization of circulating lymphocytes to a site of inflammation is paramount for the development and maintenance of an immune response. In vitro studies…”
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P-Selectin Can Support Both Th1 and Th2 Lymphocyte Rolling in the Intestinal Microvasculature by Bonder, Claudine S., Norman, M. Ursula, MacRae, Tara, Mangan, Paul R., Weaver, Casey T., Bullard, Daniel C., McCafferty, Donna-Marie, Kubes, Paul

“…Lymphocyte localization to inflammatory sites is paramount for developing and maintaining an immune response. Rolling is the first step in recruitment, but our…”
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Both Th1 and Th2 Cells Require P-Selectin Glycoprotein Ligand-1 for Optimal Rolling on Inflamed Endothelium by Mangan, Paul R., O'Quinn, Darrell, Harrington, Laurie, Bonder, Claudine S., Kubes, Paul, Kucik, Dennis F., Bullard, Daniel C., Weaver, Casey T.

“…The acquisition of homing receptors that redirect lymphocyte trafficking to nonlymphoid tissues after antigen encounter is a fundamental aspect of effector…”
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Chimeric SOD2/3 inhibits at the endothelial-neutrophil interface to limit vascular dysfunction in ischemia-reperfusion by Bonder, Claudine S, Knight, Derrice, Hernandez-Saavedra, Daniel, McCord, Joe M, Kubes, Paul

“…After an ischemic episode, reperfusion causes profound oxidative stress in the vasculature of the afflicted tissue/organ. The dysregulated accumulation of…”
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Differential responses of human monocytes and macrophages to IL-4 and IL-13 by Hart, Prue H., Bonder, Claudine S., Balogh, Julianna, Dickensheets, Harold L., Donnelly, Raymond P., Finlay‐Jones, John J.

“…The primary interleukin‐4 (IL‐4) receptor complex on monocytes (type I IL‐4 receptor) includes the 140‐kDa α chain (IL‐4Rα) and the IL‐2 receptor γ chain, γc,…”
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The future of GI and liver research: editorial perspectives: II. Modulating leukocyte recruitment to splanchnic organs to reduce inflammation by Bonder, Claudine S, Kubes, Paul

“…A hallmark feature of intestinal inflammation is the recruitment and extravasation of numerous cell types from the blood to the afflicted site. Much of what we…”
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Interleukin‐4 regulation of human monocyte and macrophage interleukin‐10 and interleukin‐12 production. Role of a functional interleukin‐2 receptor γ‐chain by Bonder, C S, Finlay-Jones, J J, Hart, P H

“…Interleukin‐4 (IL‐4) is the prototypic type 2 immunoregulatory cytokine that can suppress the production of many monocyte and macrophage pro‐inflammatory…”
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Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs by Andonegui, G.

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Involvement of the IL-2 receptor gamma-chain (gammac) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production by Bonder, C S, Dickensheets, H L, Finlay-Jones, J J, Donnelly, R P, Hart, P H

“…IL-4 has potent anti-inflammatory properties on monocytes and suppresses both IL-1beta and TNF-alpha production. Well-characterized components of the IL-4…”
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Diminished responses to IL-13 by human monocytes differentiated in vitro: role of the IL-13R alpha 1 chain and STAT6 by Hart, PH, Bonder, C S, Balogh, J, Dickensheets, H L, Vazquez, N, Davies, KVL, Finlay-Jones, J J, Donnelly, R P

“…The primary IL-13 receptor complex on human monocytes is believed to be a heterodimer comprised of the IL-4R alpha chain and the IL-2R gamma chain ( gamma…”
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IFN-gamma downregulates interleukin-4 functional activity on monocytes by multiple mechanisms by Bonder, Claudine S, Davies, Kate V L, Hosszu, Emma K, Finlay-Jones, John J, Hart, Prue H

“…Interleukin-4 (IL-4) has potent anti-inflammatory properties on monocytes and suppresses lipopolysaccharide (LPS)-induced tumor necrosis factor-alpha…”
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ENDOGENOUS INTERFERON-α PRODUCTION BY DIFFERENTIATING HUMAN MONOCYTES REGULATES EXPRESSION AND FUNCTION OF THE IL-2/IL-4 RECEPTOR γ CHAIN by Bonder, Claudine S., Davies, Kate V.L., Liu, Xiang, Hertzog, Paul J., Woodcock, Joanna M., Finlay-Jones, John J., Hart, Prue H.

“…In vitro monocyte-derived macrophages (MDMac) and synovial fluid macrophages from inflamed joints differ from monocytes in their responses to interleukin 4…”
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Interleukin (IL)-10, but not IL-4 or IL-13, inhibits cytokine production and growth in juvenile myelomonocytic leukemia cells by IVERSEN, P. O, HART, P. H, BONDER, C. S, LOPEZ, A. F

“…Juvenile myelomonocytic leukemia (JMML) carries a poor prognosis. The endogenous production of cytokines by the JMML cells contributes to their growth and…”
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Control of major histocompatibility complex class II expression on human monocytes by interleukin‐4: regulatory effect of lipopolysaccharide by HART, P. H., BONDER, C. S., JONES, C. A., FINLAY‐JONES, J. J.

“…Interleukin‐4 (IL‐4), like interferon‐γ (IFN‐γ), stimulates monocyte major histocompatibility complex (MHC) class II expression and thus, by increasing antigen…”
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