Search Results - "Bonchi, Carlo"
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Iron and Acinetobacter baumannii Biofilm Formation
Published in Pathogens (Basel) (18-08-2014)“…Acinetobacter baumannii is an emerging nosocomial pathogen, responsible for infection outbreaks worldwide. The pathogenicity of this bacterium is mainly due to…”
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Acinetobacter baumannii Biofilm Formation in Human Serum and Disruption by Gallium
Published in Antimicrobial agents and chemotherapy (01-01-2017)“…Biofilm-associated infections caused by Acinetobacter baumannii are extremely recalcitrant to antibiotic treatment. We report that A. baumannii develops a…”
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Role of Iron Uptake Systems in Pseudomonas aeruginosa Virulence and Airway Infection
Published in Infection and immunity (01-08-2016)“…Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic lung infections in cystic fibrosis patients. Iron is essential for…”
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Promises and failures of gallium as an antibacterial agent
Published in Future microbiology (01-03-2014)“…Gallium has a long history as a diagnostic and chemotherapeutic agent. The pharmacological properties of Ga(III) rely on chemical mimicry; when Ga(III) is…”
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Repurposing of gallium-based drugs for antibacterial therapy
Published in BioFactors (Oxford) (01-05-2014)“…While the occurrence and spread of antibiotic resistance in bacterial pathogens is vanishing current anti‐infective therapies, the antibiotic discovery…”
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Pyochelin potentiates the inhibitory activity of gallium on Pseudomonas aeruginosa
Published in Antimicrobial agents and chemotherapy (01-09-2014)“…Gallium (Ga) is an iron mimetic that has successfully been repurposed for antibacterial chemotherapy. To improve the antibacterial potency of Ga on Pseudomonas…”
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Pyoverdine and proteases affect the response of Pseudomonas aeruginosa to gallium in human serum
Published in Antimicrobial agents and chemotherapy (01-09-2015)“…Gallium is an iron mimetic which has recently been repurposed as an antibacterial agent due to its capability to disrupt bacterial iron metabolism. In this…”
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The dual personality of iron chelators: growth inhibitors or promoters?
Published in Antimicrobial agents and chemotherapy (01-05-2013)Get full text
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Biological Characterization and in Vivo Assessment of the Activity of a New Synthetic Macrocyclic Antifungal Compound
Published in Journal of medicinal chemistry (28-04-2016)“…We recently identified a novel family of macrocyclic amidinoureas showing potent antifungal activity against Candida spp. In this study, we demonstrate the…”
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Cell aggregation promotes pyoverdine-dependent iron uptake and virulence in Pseudomonas aeruginosa
Published in Frontiers in microbiology (28-08-2015)“…In Pseudomonas aeruginosa the Gac signaling system and the second messenger cyclic diguanylate (c-di-GMP) participate in the control of the switch between…”
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