Search Results - "Boncheva, Mila"
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The Extent of Orthorhombic Lipid Phases in the Stratum Corneum Determines the Barrier Efficiency of Human Skin In Vivo
Published in Journal of investigative dermatology (01-02-2010)Get full text
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2
Molecular organization of the lipid matrix in intact Stratum corneum using ATR-FTIR spectroscopy
Published in Biochimica et biophysica acta (01-05-2008)“…ATR-FTIR spectroscopy is useful in investigating the lateral organization of Stratum corneum (SC) lipids in full-thickness skin. Based on studies of the…”
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Beyond Molecules: Self-Assembly of Mesoscopic and Macroscopic Components
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-2002)“…Self-assembly is a process in which components, either separate or linked, spontaneously form ordered aggregates. Self-assembly can occur with components…”
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Visualization of Epidermal Reservoir Formation from Topical Diclofenac Gels by Raman Spectroscopy
Published in Journal of pain research (01-01-2020)“…This work investigated whether topical pain relief diclofenac gels can form a diclofenac reservoir in the epidermal and dermal layers of human skin. Excised…”
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Time-Dependent Differences in the Effects of Oleic Acid and Oleyl Alcohol on the Human Skin Barrier
Published in Molecular pharmaceutics (04-12-2023)“…Oleic acid and oleyl alcohol are commonly used permeation and penetration enhancers to facilitate topical drug delivery. Here, we aimed to better understand…”
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Optimization of topical formulations using a combination of in vitro methods to quantify the transdermal passive diffusion of drugs
Published in International journal of pharmaceutics (25-05-2022)“…[Display omitted] This paper describes a new approach to the early-stage optimization of topical products and selection of lead formulation candidates. It…”
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Depth profiling of Stratum corneum hydration in vivo: a comparison between conductance and confocal Raman spectroscopic measurements
Published in Experimental dermatology (01-10-2009)“…: The high‐frequency electrical conductance of tape‐stripped human skin in vivo can be used to evaluate the hydration profile of Stratum corneum (SC)…”
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Magnetic Self-Assembly of Three-Dimensional Surfaces from Planar Sheets
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-2005)“…This report describes the spontaneous folding of flat elastomeric sheets, patterned with magnetic dipoles, into free-standing, 3D objects that are the…”
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Topical Diclofenac Reduces Joint Synovitis in Hand Osteoarthritis: A Pilot Investigation Using Fluorescent Optical Imaging
Published in Journal of pain research (31-07-2024)“…Synovitis, the inflammation of joint synovia, is a prominent feature of osteoarthritis (OA) manifested by enhanced synovial vascularity, endothelial leakage,…”
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10
In vitro skin penetration of fragrances: Trapping the evaporated material can enhance the dermal absorption of volatile chemicals
Published in Toxicology in vitro (01-10-2011)“…[Display omitted] ► The article describes an in vitro study of the evaporation and skin absorption of fragrances. ► Evaporation rates measured on skin and on…”
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Biomimetic Self-Assembly of a Functional Asymmetrical Electronic Device
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-2002)“…This paper introduces a biomimetic strategy for the fabrication of asymmetrical, three-dimensional electronic devices modeled on the folding of a chain of…”
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12
Plasticity in Self-Assembly: Templating Generates Functionally Different Circuits from a Single Precursor
Published in Angewandte Chemie International Edition (28-07-2003)“…The structures and patterns of electrical connections within 3D self‐assembled aggregates can be templated by the geometry of the space in which the…”
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Biomimetic Fabrication of 3D Structures by Spontaneous Folding of Tapes
Published in Journal of the American Chemical Society (26-07-2006)“…This paper describes a biomimetic strategy for the fabrication of 3D structuresincluding an electrically functional light detectormodeled on the folding of…”
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14
Correlation between the properties of the lipid matrix and the degrees of integrity and cohesion in healthy human Stratum corneum
Published in Experimental dermatology (01-03-2011)“…: The correlation between the degrees of integrity and cohesion in healthy human Stratum corneum (SC) and the properties of the SC lipid matrix could be…”
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15
The physical chemistry of the stratum corneum lipids
Published in International journal of cosmetic science (01-12-2014)“…Synopsis The extracellular matrix of stratum corneum (SC) participates actively in the defensive performance of human skin. Understanding its physicochemical…”
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Visualisation of drug distribution in skin using correlative optical spectroscopy and mass spectrometry imaging
Published in Journal of controlled release (01-12-2023)“…A correlative methodology for label-free chemical imaging of soft tissue has been developed, combining non-linear optical spectroscopies and mass spectrometry…”
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The impact of surface loading and dosing scheme on the skin uptake of fragrances
Published in Toxicology in vitro (01-12-2013)“…•The article describes an in vitro study of the skin uptake of fragrances.•The correlations between fractional uptake and loading differ between…”
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Nonspecific and Thiol-Specific Binding of DNA to Gold Nanoparticles
Published in Langmuir (02-09-2003)“…Modifying colloidal gold particles with DNA is a new interesting approach in the development of genetic biosensors. Normally the modification is designed to…”
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In vitro model systems for studying the impact of organic chemicals on the skin barrier lipids
Published in Biochimica et biophysica acta (01-01-2014)“…This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the…”
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