Search Results - "Boncek, V"

1192U90 in animal tests that predict antipsychotic efficacy, anxiolysis, and extrapyramidal side effects by Rigdon, Greg C., Norman, Mark H., Cooper, Barrett R., Howard, James L., Boncek, Virginia M., Faison, Walter L., Nanry, Kevin P., Pollard, Gerald T.

“…1192U90 was developed on the assumption that antagonism of 5-HT2 receptors efficacy yields more potently than D2 receptors against positive and negative…”
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Evidence for monoaminergic involvement in triadimefon-induced hyperactivity by CROFTON, K. M, BONCEK, V. M, MACPHAIL, R. C

“…Triadimefon is a triazole fungicide that produces hyperactivity in both mice and rats similar to that seen following administration of compounds with…”
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Prenatal or postnatal exposure to bis(tri-n-butyltin)oxide in the rat: postnatal evaluation of teratology and behavior by Crofton, K M, Dean, K F, Boncek, V M, Rosen, M B, Sheets, L P, Chernoff, N, Reiter, L W

“…The results of a series of screening tests to determine the potential teratogenicity and neurotoxicity of developmental exposure to TBTO in rats are presented…”
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The pharmacologic evaluation of locomotor activity versus inflammatory parameters in rat adjuvant arthritis by Selph, J L, Boncek, V M, Soroko, F E, Harris, T M, Cochran, F R

“…Adjuvant-induced arthritis (AA) is an experimental model of inflammatory joint disease in the rat which mimics rheumatoid arthritis. Although paw inflammation…”
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Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases by Conway, J G, Andrews, R C, Beaudet, B, Bickett, D M, Boncek, V, Brodie, T A, Clark, R L, Crumrine, R C, Leenitzer, M A, McDougald, D L, Han, B, Hedeen, K, Lin, P, Milla, M, Moss, M, Pink, H, Rabinowitz, M H, Tippin, T, Scates, P W, Selph, J, Stimpson, S A, Warner, J, Becherer, J D

“…Tumor necrosis factor-alpha (TNF)-converting enzyme (TACE) cleaves the precursor form of TNF, allowing the mature form to be secreted into the extracellular…”
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Hyperactivity induced by triadimefon, a triazole fungicide by Crofton, K M, Boncek, V M, Reiter, L W

“…Triadimefon is an agriculturally important triazole fungicide. The present experiments were conducted to characterize the effects of triadimefon on a measure…”
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P 2–P 3 conformationally constrained ketoamide-based inhibitors of cathepsin K by Barrett, David G., Boncek, Virginia M., Catalano, John G., Deaton, David N., Hassell, Anne M., Jurgensen, Cynthia H., Long, Stacey T., McFadyen, Robert B., Miller, Aaron B., Miller, Larry R., Payne, J. Alan, Ray, John A., Samano, Vicente, Shewchuk, Lisa M., Tavares, Francis X., Wells-Knecht, Kevin J., Willard, Derril H., Wright, Lois L., Zhou, Hui-Qiang Q.

“…An orally bioavailable series of ketoamide-based cathepsin K inhibitors with good pharmacokinetic properties has been identified. Starting from a potent…”
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