Search Results - "Bonato, Pierina S."
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A highly sensitive LC–MS–MS assay for analysis of midazolam and its major metabolite in human plasma: Applications to drug metabolism
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05-08-2005)“…The present report describes a rapid, selective and a highly sensitive assay for midazolam (MDZ) and its major metabolite 1-hydroxymidazolam (1-OH-MDZ) in…”
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Albendazole Sulfoxide Plasma Levels and Efficacy of Antiparasitic Treatment in Patients With Parenchymal Neurocysticercosis
Published in Clinical infectious diseases (13-11-2019)“…Abstract Background The efficacy of albendazole therapy in patients with parenchymal neurocysticercosis (NCC) is suboptimal. Plasma levels of albendazole…”
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Pharmacokinetics of combined treatment with praziquantel and albendazole in neurocysticercosis
Published in British journal of clinical pharmacology (01-07-2011)“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • The antiparasitic drugs albendazole and prazoquantel have been used together before for geohelminths, echinococcosis…”
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Enantioselective analysis of ibuprofen in human plasma by anionic cyclodextrin-modified electrokinetic chromatography
Published in Electrophoresis (01-09-2002)“…This paper reports the development of a rapid method for the enantioselective analysis of the nonsteroidal anti‐inflammatory drug ibuprofen in human plasma by…”
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Medical management of neurocysticercosis
Published in Expert opinion on pharmacotherapy (01-12-2011)“…Neurocysticercosis (NCC) is considered to be the most common cause of acquired epilepsy worldwide. Formerly restricted to palliative measures, therapy for NCC…”
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Fluoxetine induces preventive and complex effects against colon cancer development in epithelial and stromal areas in rats
Published in Toxicology letters (28-07-2011)“…► We investigated fluoxetine against early colon cancer development. ► Fluoxetine treatment increased colonic serotonin levels. ► Fluoxetine and serotonin were…”
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Capillary electrophoresis and hollow fiber liquid-phase microextraction for the enantioselective determination of albendazole sulfoxide after biotransformation of albendazole by an endophytic fungus
Published in Electrophoresis (01-10-2011)“…Hollow fiber liquid‐phase microextraction and CE were applied for the determination of albendazole sulfoxide (ASOX) enantiomers in liquid culture medium after…”
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Determination of β-artemether and its main metabolite dihydroartemisinin in plasma employing liquid-phase microextraction prior to liquid chromatographic–tandem mass spectrometric analysis
Published in Talanta (Oxford) (15-05-2010)“…A method for the determination of artemether (ART) and its main metabolite dihydroartemisinin (DHA) in plasma employing liquid-phase microextraction (LPME) for…”
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Enantioselective analysis of primaquine and its metabolite carboxyprimaquine by capillary electrophoresis
Published in Electrophoresis (01-08-2004)“…An enantioselective capillary electrophoresis method for the simultaneous determination of primaquine (PQ) and carboxyprimaquine (CPQ) in rat liver…”
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Liquid chromatographic separation of aqueous species of Cr(VI) and Cr(III)
Published in Journal of Chromatography A (21-11-1997)“…Although chromium can be present in aqueous solutions as Cr(VI) or as any of various kinetically stable forms of Cr(III), whose distribution depends on the…”
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Stereoselective liquid chromatographic determination of 1′‐oxobufuralol and 1′‐hydroxybufuralol in rat liver microsomal fraction using hollow‐fiber liquid‐phase microextraction for sample preparation
Published in Journal of separation science (01-12-2011)“…A three‐phase hollow‐fiber liquid‐phase microextraction (HF‐LPME) method for the stereoselective determination of bufuralol metabolites 1′‐oxobufuralol…”
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Propolis extract release evaluation from topical formulations by chemiluminescence and HPLC
Published in Journal of pharmaceutical and biomedical analysis (03-05-2006)“…Propolis is a resinous bee hive product that has many biological activities. Among these activities, the antioxidant activity deserves special interest since…”
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Enantioselective analysis of omeprazole in pharmaceutical formulations by chiral high-performance liquid chromatography and capillary electrophoresis
Published in Journal of the Brazilian Chemical Society (01-04-2004)“…We developed two sensitive and simple assay procedures based on high- performance liquid chromatography and capillary electrophoresis (CE) for the…”
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Biomimetic oxidation of praziquantel catalysed by metalloporphyrins
Published in Journal of molecular catalysis. A, Chemical (01-02-2005)“…This paper reports an HPLC–MS/MS investigation of praziquantel (anthelmintic agent) oxidation by iodosylbenzene in an organic medium, using iron(III)…”
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Enantiomeric Resolution of Drugs and Metabolites in Polysaccharide- and Protein-Based Chiral Stationary Phases
Published in Journal of the Brazilian Chemical Society (2002)“…Several chiral stationary phases based on polysaccharide derivatives and proteins were evaluated for the resolution of some chiral drugs and their metabolites…”
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LC-MS-MS identification of drug metabolites obtained by metalloporphyrin mediated oxidation
Published in Journal of the Brazilian Chemical Society (01-04-2003)“…In this paper we report the application of liquid chromatography-mass spectrometry (LC-MS-MS) to the identification of the products formed by oxidation of…”
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Determination of ametryn in river water, river sediment and bivalve mussels by liquid chromatography-tandem mass spectrometry
Published in Journal of the Brazilian Chemical Society (2009)“…Analytical methods employing liquid chromatography-mass spectrometry (LC-MS-MS) for ametryn determination in river water, river sediment and in freshwater…”
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A simple method for the quantitative analysis of tyrosol by hplc in liquid Czapek Cultures from endophytic fungi
Published in Journal of the Brazilian Chemical Society (2009)“…Tyrosol is a possible quorum sensing molecule in endophytic fungi. High-performance liquid chromatography (HPLC) coupled with diode array detector (DAD) was…”
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Fast HPLC analysis of omeprazole, 5-hydroxyomeprazole and omeprazole sulfone in liquid culture medium using a monolithic column for application in biotransformation studies with fungi
Published in Journal of the Brazilian Chemical Society (01-06-2011)“…A fast liquid chromatography method was developed and validated for the simultaneous determination of omeprazole (OMZ), 5-hydroxyomeprazole (5-HOMZ) and…”
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