Search Results - "Bonar, Holly"
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Automated Oxygen Gradient Ektacytometry: A Novel Biomarker in Sickle Cell Anemia
Published in Frontiers in physiology (25-03-2021)“…Sickle cell anemia (SCA) is a hereditary hemoglobinopathy with a variable phenotype. There is no single biomarker that adequately predicts disease severity and…”
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Sildenafil does not improve nitric oxide‐mediated endothelium‐dependent vascular responses in smokers
Published in British journal of clinical pharmacology (01-02-2004)“…Aims To examine the hypothesis that sildenafil, a phosphodiesterase type 5 inhibitor that inhibits cGMP breakdown, could enhance nitric oxide‐mediated…”
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Early initiation of hydroxyurea (hydroxycarbamide) using individualised, pharmacokinetics‐guided dosing can produce sustained and nearly pancellular expression of fetal haemoglobin in children with sickle cell anaemia
Published in British journal of haematology (01-08-2021)“…Summary Hydroxyurea (hydroxycarbamide) is an effective treatment for sickle cell anaemia (SCA), but clinical responses depend primarily upon the degree of…”
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Pharmacokinetics-Guided Dosing of Hydroxyurea Can Achieve Near-Pancellular Fetal Hemoglobin Expression in Sickle Cell Anemia: F-Cell Analysis As a Benchmark for Disease-Modifying Therapy
Published in Blood (13-11-2019)“…▪ Background: Hydroxyurea is the standard of care for children with sickle cell anemia (SCA). We have developed and prospectively validated a population…”
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Design and Implementation of Quality Analysis for BD FACS Lyse Wash Assistant
Published in American journal of clinical pathology (01-10-2014)Get full text
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