Search Results - "Bonafé, Nathalie"

TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis by Demento, Stacey L, Bonafé, Nathalie, Cui, Weiguo, Kaech, Susan M, Caplan, Michael J, Fikrig, Erol, Ledizet, Michel, Fahmy, Tarek M

“…Vaccines that activate humoral and cell-mediated immune responses are urgently needed for many infectious agents, including the flaviviruses dengue and West…”
Get full text

Glyceraldehyde-3-phosphate dehydrogenase binds to the au-rich 3' untranslated region of colony-stimulating factor-1 (CSF-1) messenger RNA in human ovarian cancer cells : Possible role in CSF-1 posttranscriptional regulation and tumor phenotype by BONAFE, Nathalie, GILMORE-HEBERT, Maureen, FOLK, Nancy L, AZODI, Masoud, YI ZHOU, CHAMBERS, Setsuko K

“…The overexpression of the colony-stimulating factor-1(CSF-1) by epithelial ovarian cancer cells enhances invasiveness and metastatic properties, contributing…”
Get full text

Fusion Loop Peptide of the West Nile Virus Envelope Protein Is Essential for Pathogenesis and Is Recognized by a Therapeutic Cross-Reactive Human Monoclonal Antibody by Sultana, Hameeda, Foellmer, Harald G, Neelakanta, Girish, Oliphant, Theodore, Engle, Michael, Ledizet, Michel, Krishnan, Manoj N, Bonafe, Nathalie, Anthony, Karen G, Marasco, Wayne A, Kaplan, Paul, Montgomery, Ruth R, Diamond, Michael S, Koski, Raymond A, Fikrig, Erol

“…West Nile virus is an emerging pathogen that can cause fatal neurological disease. A recombinant human mAb, mAb11, has been described as a candidate for the…”
Get full text

A recombinant West Nile virus envelope protein vaccine candidate produced in Spodoptera frugiperda expresSF+ cells by Bonafé, Nathalie, Rininger, Joseph A., Chubet, Richard G., Foellmer, Harald G., Fader, Stacey, Anderson, John F., Bushmich, Sandra L., Anthony, Karen, Ledizet, Michel, Fikrig, Erol, Koski, Raymond A., Kaplan, Paul

“…In this study, a recombinant truncated West Nile virus envelope protein antigen (rWNV-E) was produced in serum-free cultures of the expresSF+ insect cell line…”
Get full text

Antibodies Targeting Linear Determinants of the Envelope Protein Protect Mice against West Nile Virus by Ledizet, Michel, Kar, Kalipada, Foellmer, Harald G., Bonafé, Nathalie, Anthony, Karen G., Gould, L. Hannah, Bushmich, Sandra L., Fikrig, Erol, Koski, Raymond A.

“…The flavivirus envelope (E) protein mediates cellular attachment and fusion with host cell membranes and is recognized by virus-neutralizing…”
Get full text

West Nile Virus Envelope Protein Inhibits dsRNA-Induced Innate Immune Responses by Arjona, Alvaro, Ledizet, Michel, Anthony, Karen, Bonafe, Nathalie, Modis, Yorgo, Town, Terrence, Fikrig, Erol

“…The immune response against viral infection relies on the early production of cytokines that induce an antiviral state and trigger the activation of immune…”
Get full text

Epidermal growth factor receptor peptide vaccination induces cross-reactive immunity to human EGFR, HER2, and HER3 by Doyle, Hester A., Koski, Raymond A., Bonafé, Nathalie, Bruck, Ross A., Tagliatela, Stephanie M., Gee, Renelle J., Mamula, Mark J.

“…Current treatments for tumors expressing epidermal growth factor receptor (EGFR) include anti-EGFR monoclonal antibodies, often used in conjunction with the…”
Get full text

The Multifunctional Protein Glyceraldehyde-3-Phosphate Dehydrogenase Is Both Regulated and Controls Colony-Stimulating Factor-1 Messenger RNA Stability in Ovarian Cancer by Zhou, Yi, Yi, Xiaofang, Stoffer, Jha'nae B, Bonafe, Nathalie, Gilmore-Hebert, Maureen, McAlpine, Jessica, Chambers, Setsuko K

“…Although glyceraldehyde-3-phosphate dehydrogenase's (GAPDH) predilection for AU-rich elements has long been known, the expected connection between GAPDH and…”
Get full text

Structural studies of human glioma pathogenesis-related protein 1 by Asojo, Oluwatoyin A., Koski, Raymond A., Bonafé, Nathalie

“…Human glioma pathogenesis‐related protein 1 (GLIPR1) is a membrane protein that is highly upregulated in brain cancers but is barely detectable in normal brain…”
Get full text

Targeting multiple ErbB family members by EGFR peptide immunization. (VAC12P.1016) by Doyle, Hester, Koski, Raymond, Bonafé, Nathalie, Bruck, Ross, Tagliatela, Stephanie, Gee, Renelle, Mamula, Mark

“…A major breakthrough in cancer treatment has been the development of monoclonal antibodies targeting tumor antigens. A majority of solid tumors overexpress the…”
Get full text

Abstract 4746: Structural studies of human glioma pathogenesis-related protein 1(GLIPR1) by Asojo, Oluwatoyin A., Koski, Raymond A., Bonafé, Nathalie

“…Human glioma pathogenesis-related protein 1 (GLIPR1) is a membrane protein that is highly upregulated in brain cancers but barely detectable in normal brain…”
Get full text

Tropomyosin Inhibits the Glutaraldehyde-Induced Cross-Link between the Central 48-kDa Fragment of Myosin Head and Segment 48-67 in Actin Subdomain 2 by Bonafe, Nathalie, Mathieu, Magali, Kassab, Ridha, Chaussepied, Patrick

“…The glutaraldehyde-induced cross-linking of the F-actin-myosin head (S1) complex, previously described [Bertrand et al. (1988) Biochemistry 27, 5728-5736], was…”
Get full text

Expression, purification, crystallization and preliminary X-ray analysis of a truncated soluble domain of human glioma pathogenesis-related protein 1 by Bonafé, Nathalie, Zhan, Bin, Bottazzi, Maria Elena, Perez, Oriana A., Koski, Raymond A., Asojo, Oluwatoyin A.

“…Glioma pathogenesis‐related protein 1 (GLIPR1) is a member of the CAP superfamily that includes proteins from a wide range of eukaryotic organisms. The…”
Get full text

Correlation of tumor phenotype with c-fms proto-oncogene expression in an in vivo intraperitoneal model for experimental human breast cancer metastasis by Toy, Eugene P, Bonafé, Nathalie, Savlu, Asim, Zeiss, Caroline, Zheng, Wenxin, Flick, Maryann, Chambers, Setsuko K

“…Although proto-oncogene expression has been shown to correlate with clinical outcome in breast carcinoma, an experimental model has not been proposed to study…”
Get full text

Drosophila myosin V is required for larval development and spermatid individualization by Mermall, Valerie, Bonafé, Nathalie, Jones, Lynn, Sellers, James R., Cooley, Lynn, Mooseker, Mark S.

“…Class V myosins are multifunctional molecular motors implicated in vesicular traffic, RNA transport, and mechanochemical coupling of the actin and…”
Get full text

SGK1, a potential regulator of c-fms related breast cancer aggressiveness by Tangir, Jacob, Bonafé, Nathalie, Gilmore-Hebert, Maureen, Henegariu, Octavian, Chambers, Setsuko K

“…The aggressive behavior of breast cancer cells can at times be modulated by hormonal mechanisms. Exposure to glucocorticoids (GC) has been shown to stimulate…”
Get full text

A recombinant West Nile virus envelope protein vaccine candidate produced in Spodoptera frugiperda expres SF+ cells by Bonafé, Nathalie, Rininger, Joseph A, Chubet, Richard G, Foellmer, Harald G, Fader, Stacey, Anderson, John F, Bushmich, Sandra L, Anthony, Karen, Ledizet, Michel, Fikrig, Erol, Koski, Raymond A, Kaplan, Paul

“…Abstract In this study, a recombinant truncated West Nile virus envelope protein antigen (rWNV-E) was produced in serum-free cultures of the expres SF+ insect…”
Get full text

Molecular characterization of myosin V from Drosophila melanogaster by Bonafé, N, Sellers, J R

“…Recent studies have revealed unconventional myosin V to be an important actin-based molecular motor involved in vesicular movement. In this paper we report the…”
Get full text

The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls CSF-1 mRNA stability in ovarian cancer by Zhou, Yi, Yi, Xiaofang, Stoffer, Jha’Nae B., Bonafe, Nathalie, Gilmore-Hebert, Maureen, McAlpine, Jessica, Chambers, Setsuko K.

“…Although GAPDH’s predilection for AU-rich elements has long been known, the expected connection between GAPDH and control of mRNA stability has never been…”
Get full text

Photochemical cross‐linking of the skeletal myosin head heavy chain to actin subdomain‐1 at Arg95 and Arg28 by BONAFÉ, Nathalie, CHAUSSEPIED, Patrick, CAPONY, Jean Paul, DERANCOURT, Jean, KASSAB, Ridha

“…F‐actin specifically substituted with the photocross‐linker, p‐azidophenylglyoxal, at Arg95 and Arg28 was isolated and characterized. Upon complexation with…”
Get full text