Search Results - "Bonab, Maziar Ashrafian"
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Insights into the Role of Matrix Metalloproteinases in Precancerous Conditions and in Colorectal Cancer
Published in Cancers (10-12-2021)“…Colorectal cancer (CRC) is the third and second cancer for incidence and mortality worldwide, respectively, and is becoming prevalent in developing countries…”
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ANRIL as a prognostic biomarker in colon pre-cancerous lesion detection via non-invasive sampling
Published in Genes & Genetic Systems (01-12-2021)“…Long non-coding RNAs have been proposed as biomarkers for the detection, prevention and screening of various malignancies. In this study, two lncRNAs (ANRIL…”
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3
Mapping Post-Glacial expansions: The Peopling of Southwest Asia
Published in Scientific reports (06-01-2017)“…Archaeological, palaeontological and geological evidence shows that post-glacial warming released human populations from their various climate-bound refugia…”
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Oncogenic Role of Connective Tissue Growth Factor Is Associated with Canonical TGF-β Cascade in Colorectal Cancer
Published in Genes (14-04-2022)“…TGF-β signaling pathways promote tumour development and control several downstream genes such as CTGF and MMPs. This study aimed to investigate the association…”
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APC and AXIN2 Are Promising Biomarker Candidates for the Early Detection of Adenomas and Hyperplastic Polyps
Published in Cancer informatics (2020)“…Aberrant activation of the WNT/CTNNB1 pathway is notorious in colorectal cancer (CRC). Here, we demonstrate that the expression of specific and crucial WNT…”
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The Application of Gene Expression Profiling in Predictions of Occult Lymph Node Metastasis in Colorectal Cancer Patients
Published in Biomedicines (02-03-2018)“…A key factor in determining the likely outcome for a patient with colorectal cancer is whether or not the tumour has metastasised to the lymph…”
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The Differential DNA Hypermethylation Patterns of microRNA-137 and microRNA-342 Locus in Early Colorectal Lesions and Tumours
Published in Biomolecules (Basel, Switzerland) (21-09-2019)“…Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide, representing 13% of all cancers. The role of epigenetics in cancer diagnosis and…”
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Afghanistan's ethnic groups share a Y-chromosomal heritage structured by historical events
Published in PloS one (28-03-2012)“…Afghanistan has held a strategic position throughout history. It has been inhabited since the Paleolithic and later became a crossroad for expanding…”
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GJA4/Connexin 37 Mutations Correlate with Secondary Lymphedema Following Surgery in Breast Cancer Patients
Published in Biomedicines (22-02-2018)“…Lymphedema is a condition resulting from mutations in various genes essential for lymphatic development and function, which leads to obstruction of the…”
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The effective function of circular RNA in colorectal cancer
Published in Cancer cell international (17-09-2021)“…Colorectal cancer (CRC) is the 3rd most common type of cancer worldwide. Late detection plays role in one-third of annual mortality due to CRC. Therefore, it…”
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Lack of association between VEGF -2578C/A polymorphism and risk of colorectal cancer in an Iranian population
Published in Gastroenterology and hepatology from bed to bench (2020)“…Here, we evaluated the VEGF gene -2578C/A polymorphism as a potential susceptibility factor in colorectal cancer (CRC) occurrence amongst Iranian CRC patients…”
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Influences of history, geography, and religion on genetic structure: the Maronites in Lebanon
Published in European journal of human genetics : EJHG (01-03-2011)“…Cultural expansions, including of religions, frequently leave genetic traces of differentiation and in-migration. These expansions may be driven by complex…”
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Up regulation of long non-coding RNAs BACE1 and down regulation of LINC-PINT are associated with CRC clinicopathological characteristics
Published in Molecular biology reports (01-11-2022)“…Background Long non-coding RNAs (LncRNAs) are known to have regulatory consequences for aberrant gene expression in cancers. The aim of this study was to…”
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14
ANRIL as a prognostic biomarker in colon pre-cancerous lesion detection via non-invasive sampling
Published in Genes & Genetic Systems (2022)“…Long non-coding RNAs have been proposed as biomarkers for the detection, prevention and screening of various malignancies. In this study, two lncRNAs (ANRIL…”
Get full text
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15
Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations
Published in Immunogenetics (New York) (01-02-2010)“…Killer cell immunoglobulin-like receptors ( KIR ) gene frequencies vary between populations and contribute to functional variation in immune responses to…”
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Geographical Structure of the Y‐chromosomal Genetic Landscape of the Levant: A coastal‐inland contrast
Published in Annals of human genetics (01-11-2009)“…SUMMARY We have examined the male‐specific phylogeography of the Levant and its surroundings by analyzing Y‐chromosomal haplogroup distributions using 5874…”
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Erratum to: Distribution of killer cell immunoglobulin-like receptors(KIR) and their HLA-C ligands in two Iranian populations
Published in Immunogenetics (New York) (01-04-2010)Get full text
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Is urbanization scrambling the genetic structure of human populations? A case study
Published in Heredity (01-03-2007)“…Recent population expansion and increased migration linked to urbanization are assumed to be eroding the genetic structure of human populations. We…”
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