Search Results - "Bon, Emeline"
-
1
How do voltage-gated sodium channels enhance migration and invasiveness in cancer cells?
Published in Biochimica et biophysica acta (01-10-2015)“…Voltage-gated sodium channels are abnormally expressed in tumors, often as neonatal isoforms, while they are not expressed, or only at a low level, in the…”
Get full text
Journal Article -
2
Understanding the Role of the SMN Complex Component GEMIN5 and Its Functional Relationship with Demethylase KDM6B in the Flunarizine-Mediated Neuroprotection of Motor Neuron Disease Spinal Muscular Atrophy
Published in International journal of molecular sciences (18-09-2024)“…Dysregulated RNA metabolism caused by SMN deficiency leads to motor neuron disease spinal muscular atrophy (SMA). Current therapies improve patient outcomes…”
Get full text
Journal Article -
3
SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer
Published in Nature communications (05-12-2016)“…The development of metastases largely relies on the capacity of cancer cells to invade extracellular matrices (ECM) using two invasion modes termed…”
Get full text
Journal Article -
4
Rock inhibition promotes NaV1.5 sodium channel-dependent SW620 colon cancer cell invasiveness
Published in Scientific reports (07-08-2020)“…The acquisition of invasive capacities by carcinoma cells, i.e. their ability to migrate through and to remodel extracellular matrices, is a determinant…”
Get full text
Journal Article -
5
Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization
Published in Molecular cancer (11-12-2014)“…Na(V)1.5 voltage-gated sodium channels are abnormally expressed in breast tumours and their expression level is associated with metastatic occurrence and…”
Get full text
Journal Article -
6
Rock inhibition promotes NaV1.5 sodium channel-dependent SW620 colon cancer cell invasiveness
Published in Scientific reports (07-08-2020)“…The acquisition of invasive capacities by carcinoma cells, i.e. their ability to migrate through and to remodel extracellular matrices, is a determinant…”
Get full text
Journal Article -
7
Suppression of PPARβ, and DHA treatment, inhibit NaV1.5 and NHE-1 pro-invasive activities
Published in Pflügers Archiv (01-06-2015)“…Peroxisome proliferator-activated receptor β (PPARβ) and Na V 1.5 voltage-gated sodium channels have independently been shown to regulate human breast cancer…”
Get full text
Journal Article -
8
PPARβ mRNA expression, reduced by n−3 PUFA diet in mammary tumor, controls breast cancer cell growth
Published in Biochimica et biophysica acta (01-11-2013)“…The effect of numerous anticancer drugs on breast cancer cell lines and rodent mammary tumors can be enhanced by a treatment with long-chain n−3…”
Get full text
Journal Article -
9
Phosphorylation of NHERF1 S279 and S301 differentially regulates breast cancer cell phenotype and metastatic organotropism
Published in Biochimica et biophysica acta. Molecular basis of disease (01-01-2019)“…Metastatic cancer cells are highly plastic for the expression of different tumor phenotype hallmarks and organotropism. This plasticity is highly regulated but…”
Get full text
Journal Article -
10
Rock inhibition promotes Na V 1.5 sodium channel-dependent SW620 colon cancer cell invasiveness
Published in Scientific reports (07-08-2020)“…The acquisition of invasive capacities by carcinoma cells, i.e. their ability to migrate through and to remodel extracellular matrices, is a determinant…”
Get full text
Journal Article -
11
Suppression of PPAR[beta], and DHA treatment, inhibit Na^sub V^1.5 and NHE-1 pro-invasive activities
Published in Pflügers Archiv (01-06-2015)“…Peroxisome proliferator-activated receptor [beta] (PPAR[beta]) and Na^sub V^1.5 voltage-gated sodium channels have independently been shown to regulate human…”
Get full text
Journal Article -
12
Ranolazine inhibits NaV 1.5-mediated breast cancer cell invasiveness and lung colonization
Published in Molecular cancer (01-01-2014)“…Doc number: 264 Abstract Background: NaV 1.5 voltage-gated sodium channels are abnormally expressed in breast tumours and their expression level is associated…”
Get full text
Journal Article