Search Results - "Bomsel, M"

HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4 cell infection: an IgA gene and functional analysis by Tudor, D, Derrien, M, Diomede, L, Drillet, A-S, Houimel, M, Moog, C, Reynes, J-M, Lopalco, L, Bomsel, M

“…AIDS is mainly a sexually transmitted disease, and accordingly, mucosal tissues are the primary sites of natural human immunodeficiency virus type-1 (HIV-1)…”
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Calcitonin gene-related peptide inhibits human immunodeficiency type 1 transmission by Langerhans cells via an autocrine/paracrine feedback mechanism by Ganor, Y., Drillet-Dangeard, A.-S., Bomsel, M.

“…Aim Peripheral neurones innervating mucosal epithelia are in direct contact with resident immune cells, including Langerhans cells (LCs). Such neurones secrete…”
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The adult penile urethra is a novel entry site for HIV-1 that preferentially targets resident urethral macrophages by Ganor, Y, Zhou, Z, Bodo, J, Tudor, D, Leibowitch, J, Mathez, D, Schmitt, A, Vacher-Lavenu, M-C, Revol, M, Bomsel, M

“…The penile urethra is routinely targeted by sexually transmitted bacterial and viral pathogens, and also represents a probable site for HIV type-1 (HIV-1)…”
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Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans-T cell conjugates by Ganor, Y, Zhou, Z, Tudor, D, Schmitt, A, Vacher-Lavenu, M-C, Gibault, L, Thiounn, N, Tomasini, J, Wolf, J-P, Bomsel, M

“…Although circumcision reduces male acquisition of human immunodeficiency virus type-1 (HIV-1) by 60%, the initial mechanisms of HIV-1 transmission at the…”
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The HIV-1 viral synapse signals human foreskin keratinocytes to secrete thymic stromal lymphopoietin facilitating HIV-1 foreskin entry by Zhou, Z, Xu, L, Sennepin, A, Federici, C, Ganor, Y, Tudor, D, Damotte, D, Barry Delongchamps, N, Zerbib, M, Bomsel, M

“…The complexity of signal transduction resulting from the contact of human immunodeficiency virus type 1 (HIV-1)-infected cells and mucosal cells has hampered…”
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Virus like particle based strategy to elicit HIV-protective antibodies to the alpha-helic regions of gp41 by Pastori, C, Tudor, D, Diomede, L, Drillet, A.S, Jegerlehner, A, Röhn, T.A, Bomsel, M, Lopalco, L

“…Abstract Natural antibodies to gp41 inhibit HIV-1 replication through the recognition of two different regions, corresponding to the leucine zipper motif in…”
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Generation of HIV-1 Virus-Like Particles expressing different HIV-1 glycoproteins by Visciano, M.L, Diomede, L, Tagliamonte, M, Tornesello, M.L, Asti, V, Bomsel, M, Buonaguro, F.M, Lopalco, L, Buonaguro, L

“…Abstract Elicitation of a potent and broadly neutralizing antibody response is the main goal of an effective preventive HIV-1 vaccine. It has been shown by us…”
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Platelets from HIV-infected cART-treated patients carry infectious viruses and predict poor immunological recovery by M. Bomsel, F. Real, C. Capron, E. Cramer, E. Rouveix

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Tissue macrophages are a major viral reservoir in male urethra of HIV-1-infected individuals under suppressive antiretroviral therapy by M. Bomsel, Y. Ganor, A. Sennepin, C.A. Dutertre, S. Cristofari, C. Capron, E.A. Eugenin, M. Revol, A. Hosmalin, F. Real

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Cell-to-Cell Contact Results in a Selective Translocation of Maternal Human Immunodeficiency Virus Type 1 Quasispecies across a Trophoblastic Barrier by both Transcytosis and Infection by Lagaye, S, Derrien, M, Menu, E, Coïto, C, Tresoldi, E, Mauclère, P, Scarlatti, G, Chaouat, G, Barré-Sinoussi, F, Bomsel, M

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P12-16. Biochemical and immunological characterization of the plant-derived candidate HIV-1 mucosal vaccine CTB-MPR by Matoba, N, Cherni, I, Kessans, S, Frater, J, Preston, K, Bomsel, M, Mor, T S

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P11-20. HIV-1 gp41-specific mucosal IgAs from highly exposed but IgG seronegative women block HIV-1 epithelial transcytosis and neutralize CD4+ cell infection by Tudor, D, Derrien, M, Diomede, L, Houimel, M, Drillet, A, Moog, C, Reynes, J, Lopalco, L, Bomsel, M

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OA011-01. Early events of human immunodeficiency virus type 1 (HIV-1) ex vivo penetration in the foreskin mimicking HIV-1 sexual transmission by Ganor, Y, Zhou, Z, Schmitt, A, Vacher-Lavenu, M, Gibault, L, Thiounn, N, Tomasini, J, Wolf, J, Bomsel, M

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P19-02. High protection of female macaques from repeated intravaginal challenges with SHIV-162P3 upon mucosal vaccination with Gp41 subunits-virosomes by Bomsel, M, Drillet, A, Roger, M, Amacker, M, Mouz, N, Lopalco, L, Devillers, G, Zurbriggen, R, Fleury, S

“…Methods We have developed a mucosal vaccine candidate based on two complementary conserved gp41 subunit antigens- a trimeric recombinant gp41 deleted in known…”
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Simian Immunodeficiency Virus Replicates to High Levels in Sooty Mangabeys without Inducing Disease by Rey-Cuillé, M A, Berthier, J L, Bomsel-Demontoy, M C, Chaduc, Y, Montagnier, L, Hovanessian, A G, Chakrabarti, L A

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Bioelectric recognition assay (BERA) by Kintzios, S, Pistola, E, Panagiotopoulos, P, Bomsel, M, Alexandropoulos, N, Bem, F, Ekonomou, G, Biselis, J, Levin, R

“…A novel biosensory method has been developed for the determination of various chemical and biological molecules by assessing their electrophysiological…”
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Cyclic FEE peptide increases human gamete fusion and potentiates its RGD-induced inhibition by Ziyyat, A., Naud-Barriant, N., Barraud-Lange, V., Chevalier, F., Kulski, O., Lemkecher, T., Bomsel, M., Wolf, J.P.

“…BACKGROUND: α6β1 integrin has been proposed to act as a sperm receptor on the mouse oocyte by interacting with spermatozoon fertilin β. We investigated, in…”
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Characterization of Pseudomonas aeruginosa-induced MDCK cell injury: glycosylation-defective host cells are resistant to bacterial killing by Apodaca, G, Bomsel, M, Lindstedt, R, Engel, J, Frank, D, Mostov, K E, Wiener-Kronish, J

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Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrin-coated vesicles essential for membrane traffic by Benichou, S, Bomsel, M, Bodéus, M, Durand, H, Douté, M, Letourneur, F, Camonis, J, Benarous, R

“…Nef is a 27-kDa myristylated protein conserved in most human immunodeficiency virus (HIV)-1, HIV-2, and simian immunodeficiency virus isolates. Simian…”
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Mouse Offspring after Microinjection of Heated Spermatozoa by Cozzi, J, Monier-Gavelle, F, Lièvre, N, Bomsel, M, Wolf, J. P

“…The thermostability of the mammalian sperm genome was previously reported, but no live offspring after conception with heated spermatozoa had yet been…”
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