Search Results - "Bombard, Yvonne"

How digital tools can advance quality and equity in genomic medicine by Bombard, Yvonne, Hayeems, Robin Z.

“…Now more than ever, digital applications are essential to accessing genetics services and optimizing their delivery. At this watershed moment, digital…”
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Clinical and psychological outcomes of receiving a variant of uncertain significance from multigene panel testing or genomic sequencing: a systematic review and meta-analysis by Mighton, Chloe, Shickh, Salma, Uleryk, Elizabeth, Pechlivanoglou, Petros, Bombard, Yvonne

“…This study systematically reviewed and synthesized the literature on psychological and clinical outcomes of receiving a variant of uncertain significance (VUS)…”
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The clinical utility of exome and genome sequencing across clinical indications: a systematic review by Shickh, Salma, Mighton, Chloe, Uleryk, Elizabeth, Pechlivanoglou, Petros, Bombard, Yvonne

“…Exome sequencing and genome sequencing have the potential to improve clinical utility for patients undergoing genetic investigations. However, evidence of…”
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The Genetic Non-Discrimination Act: critical for promoting health and science in Canada by Bombard, Yvonne, PhD, Heim-Myers, Bev, BComm

“…Bombard et al states on the criticality of the Genetic Non-Discrimination Act (GNA) for promoting the health of Canadians and ensuring Canada remains on the…”
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Effect of genetics clinical decision support tools on health-care providers’ decision making: a mixed-methods systematic review by Sebastian, Agnes, Carroll, June C., Oldfield, Leslie E., Mighton, Chloe, Shickh, Salma, Uleryk, Elizabeth, Bombard, Yvonne

“…Patient care involving genetics is challenging for nongenetics health-care providers. Clinical decision support (CDS) tools are a potential solution because…”
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Variant classification changes over time in BRCA1 and BRCA2 by Mighton, Chloe, Charames, George S., Wang, Marina, Zakoor, Kathleen-Rose, Wong, Andrew, Shickh, Salma, Watkins, Nicholas, Lebo, Matthew S., Bombard, Yvonne, Lerner-Ellis, Jordan

“…Purpose To report BRCA1 and BRCA2 ( BRCA1/2 ) variant reassessments and reclassifications between 2012 and 2017 at the Advanced Molecular Diagnostics…”
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From the patient to the population: Use of genomics for population screening by Mighton, Chloe, Shickh, Salma, Aguda, Vernie, Krishnapillai, Suvetha, Adi-Wauran, Ella, Bombard, Yvonne

“…Genomic medicine is expanding from a focus on diagnosis at the patient level to prevention at the population level given the ongoing under-ascertainment of…”
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Patient-facing digital tools for delivering genetic services: a systematic review by Whiwon, Lee, Salma, Shickh, Daniel, Assamad, Stephanie, Luca, Marc, Clausen, Cherith, Somerville, Abby, Tafler, Angela, Shaw, Robin, Hayeems, Yvonne, Bombard

“…This study systematically reviewed the literature on the impact of digital genetics tools on patient care and system efficiencies. MEDLINE and Embase were…”
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Health-care practitioners’ preferences for the return of secondary findings from next-generation sequencing: a discrete choice experiment by Jiang, Shan, Anis, Aslam H., Cromwell, Ian, Mohammadi, Tima, Schrader, Kasmintan A., Lucas, Janet, Armour, Christine M., Clausen, Marc, Bombard, Yvonne, Regier, Dean A.

“…Purpose Health-care practitioners’ (HCPs) preferences for returning secondary findings (SFs) will influence guideline compliance, shared decision-making, and…”
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Widening the lens of actionability: A qualitative study of primary care providers' views and experiences of managing secondary genomic findings by Sebastian, Agnes, Carroll, June C, Vanstone, Meredith, Clausen, Marc, Kodida, Rita, Reble, Emma, Mighton, Chloe, Shickh, Salma, Aronson, Melyssa, Eisen, Andrea, Elser, Christine, Lerner-Ellis, Jordan, Kim, Raymond H, Bombard, Yvonne

“…Most secondary genomic findings (SFs) fall in the scope of primary care practice. However, primary care providers' (PCPs) capacity to manage these findings is…”
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What do we do now?: Responding to claims of germline gene editing in humans by Allyse, Megan, Bombard, Yvonne, Isasi, Rosario, Michie, Marsha, Musunuru, Kiran, Ormond, Kelly E.

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Quality of life drives patients' preferences for secondary findings from genomic sequencing by Mighton, Chloe, Carlsson, Lindsay, Clausen, Marc, Casalino, Selina, Shickh, Salma, McCuaig, Laura, Joshi, Esha, Panchal, Seema, Semotiuk, Kara, Ott, Karen, Elser, Christine, Eisen, Andrea, Kim, Raymond H, Lerner-Ellis, Jordan, Carroll, June C, Glogowski, Emily, Schrader, Kasmintan, Bombard, Yvonne

“…There is growing impetus to include measures of personal utility, the nonmedical value of information, in addition to clinical utility in health technology…”
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Beyond medically actionable results: an analytical pipeline for decreasing the burden of returning all clinically significant secondary findings by Reble, Emma, Gutierrez Salazar, Mariana, Zakoor, Kathleen-Rose, Khalouei, Sam, Clausen, Marc, Kodida, Rita, Shickh, Salma, Mighton, Chloe, Cohn, Iris, Schrader, Kasmintan A., Kim, Raymond H., Lerner-Ellis, Jordan, Bombard, Yvonne

“…Genomic sequencing advances have increased the potential to identify secondary findings (SFs). Current guidelines recommend the analysis of 59 medically…”
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Engaging patients to improve quality of care: a systematic review by Bombard, Yvonne, Baker, G Ross, Orlando, Elaina, Fancott, Carol, Bhatia, Pooja, Casalino, Selina, Onate, Kanecy, Denis, Jean-Louis, Pomey, Marie-Pascale

“…To identify the strategies and contextual factors that enable optimal engagement of patients in the design, delivery, and evaluation of health services. We…”
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Finding the sweet spot: a qualitative study exploring patients’ acceptability of chatbots in genetic service delivery by Luca, Stephanie, Clausen, Marc, Shaw, Angela, Lee, Whiwon, Krishnapillai, Suvetha, Adi-Wauran, Ella, Faghfoury, Hanna, Costain, Gregory, Jobling, Rebekah, Aronson, Melyssa, Liston, Eriskay, Silver, Josh, Shuman, Cheryl, Chad, Lauren, Hayeems, Robin Z., Bombard, Yvonne

“…Chatbots, web-based artificial intelligence tools that simulate human conversation, are increasingly in use to support many areas of genomic medicine. However,…”
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Effectiveness of the Genomics ADvISER decision aid for the selection of secondary findings from genomic sequencing: a randomized clinical trial by Bombard, Yvonne, Clausen, Marc, Shickh, Salma, Mighton, Chloe, Casalino, Selina, Kim, Theresa H.M., Muir, Sarah M., Carlsson, Lindsay, Baxter, Nancy, Scheer, Adena, Elser, Christine, Eisen, Andrea, Panchal, Seema, Graham, Tracy, Aronson, Melyssa, Piccinin, Carolyn, Mancuso, Talia, Semotiuk, Kara, Evans, Michael, Carroll, June C., Offit, Kenneth, Robson, Mark, Hamilton, Jada G., Glogowski, Emily, Schrader, Kasmintan, Kim, Raymond H., Lerner-Ellis, Jordan, Thorpe, Kevin E., Laupacis, Andreas, Bombard, Yvonne, Armel, Susan, Aronson, Melyssa, Bayoumi, Ahmed, Bond, Ken, Caulfield, Timothy, Clausen, Marc, Clifford, Tammy, Cohn, Iris, Dhalla, Irfan, Earle, Craig C., Elser, Christine, Isaranuwatchai, Wanrudee, Kastner, Monika, Kim, Raymond H., Mujoomdar, Michelle, Robson, Mark E., Scheer, Adena, Scherer, Stephen W., Schrader, Kasmintan, Sullivan, Terrence, Thorpe, Kevin E.

“…To evaluate the effectiveness of the Genomics ADvISER (www.genomicsadviser.com) decision aid (DA) for selection of secondary findings (SF), compared with…”
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Patient and public preferences for being recontacted with updated genomic results: a mixed methods study by Mighton, Chloe, Clausen, Marc, Sebastian, Agnes, Muir, Sarah M., Shickh, Salma, Baxter, Nancy N., Scheer, Adena, Glogowski, Emily, Schrader, Kasmintan A., Thorpe, Kevin E., Kim, Theresa H. M., Lerner-Ellis, Jordan, Kim, Raymond H., Regier, Dean A., Bayoumi, Ahmed M., Bombard, Yvonne

“…Variants of uncertain significance (VUS) are frequently reclassified but recontacting patients with updated results poses significant resource challenges. We…”
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Access to novel drugs and therapeutics for children and youth: Eliciting citizens' values to inform public funding decisions by Gauvreau, Cindy L., Wight, Lisa, Subasri, Mathushan, Palmer, Antonia, Hayeems, Robin, Croker, Alysha, Abelson, Julia, Fraser, Brent, Bombard, Yvonne, Moore Hepburn, Charlotte, Wilson, Michael G., Denburg, Avram

“…Introduction The unique evidentiary, economic and ethical challenges associated with health technology assessment (HTA) of precision therapies limit access to…”
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The role of digital tools in the delivery of genomic medicine: enhancing patient-centered care by Shickh, Salma, Rafferty, Sara A., Clausen, Marc, Kodida, Rita, Mighton, Chloe, Panchal, Seema, Lorentz, Justin, Ward, Thomas, Watkins, Nicholas, Elser, Christine, Eisen, Andrea, Carroll, June C., Glogowski, Emily, Schrader, Kasmintan A., Lerner-Ellis, Jordan, Kim, Raymond H., Chitayat, David, Shuman, Cheryl, Bombard, Yvonne, Bombard, Yvonne, Armel, Susan, Aronson, Melyssa, Baxter, Nancy, Bond, Kenneth, Capo-Chichi, José-Mario, Caulfield, Timothy, Clifford, Tammy, Cohn, Iris, Dhalla, Irfan, Earle, Craig C., Evans, Mike, Graham, Tracy, Hamilton, Jada G., Isaranuwatchai, Wanrudee, Kastner, Monika, Laupacis, Andreas, Morel, Chantal F., Mujoomdar, Michelle, Offit, Kenneth, Robson, Mark E., Scheer, Adena, Scherer, Stephen W., Sullivan, Terrence, Thorpe, Kevin E.

“…Alternative models of genetic counseling are needed to meet the rising demand for genomic sequencing. Digital tools have been proposed as a method to augment…”
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P564: Doing no harm: Exploring the psychosocial impacts of receiving secondary findings from whole exome sequencing by Rokoszak, Vanessa, Hirjikaka, Daena, Clausen, Marc, Shickh, Salma, Cheung, Keven, Bombard, Yvonne

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