Search Results - "Boman, M."

Role of HOX Genes in Stem Cell Differentiation and Cancer by Bhatlekar, Seema, Boman, Bruce M., Fields, Jeremy Z.

“…HOX genes encode an evolutionarily conserved set of transcription factors that control how the phenotype of an organism becomes organized during development…”
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Human Colon Cancer Stem Cells: A New Paradigm in Gastrointestinal Oncology by Boman, Bruce M, Huang, Emina

“…For the past half century, oncologists have had systemic drugs available, agents that are able to induce tumor responses in patients with colorectal cancer…”
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Individual risk and familial liability for suicide attempt and suicide in autism: a population-based study by Hirvikoski, T, Boman, M, Chen, Q, D'Onofrio, B M, Mittendorfer-Rutz, E, Lichtenstein, P, Bölte, S, Larsson, H

“…Studies on the individual gender-specific risk and familial co-aggregation of suicidal behaviour in autism spectrum disorder (ASD) are lacking. We conducted a…”
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Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis by HUANG, Emina H, HYNES, Mark J, TAO ZHANG, GINESTIER, Christophe, DONTU, Gabriela, APPELMAN, Henry, FIELDS, Jeremy Z, WICHA, Max S, BOMAN, Bruce M

“…Although the concept that cancers originate from stem cells (SC) is becoming scientifically accepted, mechanisms by which SC contribute to tumor initiation and…”
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Sperm DNA damage is associated with an increased risk of pregnancy loss after IVF and ICSI: systematic review and meta-analysis by Zini, Armand, Boman, Jason M., Belzile, Eric, Ciampi, Antonio

“…BACKGROUND Sperm DNA damage is common amongst infertile men and may adversely impact natural reproduction, IUI-assisted reproduction and to a lesser degree IVF…”
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Overexpression of HOXA4 and HOXA9 genes promotes self‐renewal and contributes to colon cancer stem cell overpopulation by Bhatlekar, Seema, Viswanathan, Vignesh, Fields, Jeremy Z., Boman, Bruce M.

“…Because HOX genes encode master regulatory transcription factors that regulate stem cells (SCs) during development and aberrant expression of HOX genes occurs…”
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Retinoids as Chemo-Preventive and Molecular-Targeted Anti-Cancer Therapies by Hunsu, Victoria O, Facey, Caroline O B, Fields, Jeremy Z, Boman, Bruce M

“…Retinoic acid (RA) agents possess anti-tumor activity through their ability to induce cellular differentiation. However, retinoids have not yet been translated…”
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Refining outcome prediction after traumatic brain injury with machine learning algorithms by Bark, D., Boman, M., Depreitere, B., Wright, D. W., Lewén, A., Enblad, P., Hånell, A., Rostami, E.

“…Outcome after traumatic brain injury (TBI) is typically assessed using the Glasgow outcome scale extended (GOSE) with levels from 1 (death) to 8 (upper good…”
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The Role of miRNAs, miRNA Clusters, and isomiRs in Development of Cancer Stem Cell Populations in Colorectal Cancer by Stark, Victoria A, Facey, Caroline O B, Viswanathan, Vignesh, Boman, Bruce M

“…MicroRNAs (miRNAs or miRs) have a critical role in regulating stem cells (SCs) during development and altered expression can cause developmental defects and/or…”
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HOXA9 Overexpression Contributes to Stem Cell Overpopulation That Drives Development and Growth of Colorectal Cancer by Osmond, Brian, Facey, Caroline O. B., Zhang, Chi, Boman, Bruce M.

“…HOX proteins are transcription factors that regulate stem cell (SC) function, but their role in the SC origin of cancer is under-studied. Aberrant expression…”
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Mental illness, suicide and creativity: 40-Year prospective total population study by Kyaga, Simon, Landén, Mikael, Boman, Marcus, Hultman, Christina M, Långström, Niklas, Lichtenstein, Paul

“…Abstract We previously demonstrated that patients with schizophrenia or bipolar disorder and their relatives are overrepresented in creative occupations. Here,…”
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The v8-10 variant isoform of CD44 is selectively expressed in the normal human colonic stem cell niche and frequently is overexpressed in colon carcinomas during tumor development by Boman, Bruce M., Viswanathan, Vignesh, Facey, Caroline O. B., Fields, Jeremy Z., Stave, James W.

“…CD44 protein and its variant isoforms are expressed in cancer stem cells (CSCs), and various CD44 isoforms can have different functional roles in cells. Our…”
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Internet Use as a Moderator of the Relationship between Age and Depression: Implications for Older Adults by Hamilton, Boman M., Orak, Ugur, Wallace, J. Brandon

“…Technology-based interventions have been suggested to prevent depression and loneliness. However, it is not yet well-established if internet use is a…”
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APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development by Zhang, Tao, Ahn, Koree, Emerick, Brooks, Modarai, Shirin R, Opdenaker, Lynn M, Palazzo, Juan, Schleiniger, Gilberto, Fields, Jeremy Z, Boman, Bruce M

“…APC mutations drive human colorectal cancer (CRC) development. A major contributing factor is colonic stem cell (SC) overpopulation. But, the mechanism has not…”
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Chemical vapor deposition of TiN on transition metal substrates by von Fieandt, L., Larsson, T., Lindahl, E., Bäcke, O., Boman, M.

“…The growth of chemical vapor deposited TiN from a reaction gas mixture of TiCl4, N2 and H2 was investigated on three different transition metal substrates: Fe,…”
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Surface modification of iron oxides by ion bombardment – Comparing depth profiling by HAXPES and Ar ion sputtering by Fondell, M., Gorgoi, M., Boman, M., Lindblad, A.

“…•Only HAXPES taken with 3keV photons sees deep enough below the surface layer oxyhydride to reveal the correct sample composition in the bulk.•Sputtering, even…”
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Texture formation in chemical vapor deposition of Ti(C,N) by von Fieandt, L., Larsson, T., Boman, M., Lindahl, E.

“…•Reaction order is close to 1 with regards to CH3CN.•Reaction order is close to 0 with regards to TiCl4.•Coating composition unaffected by precursor partial…”
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A Review of IsomiRs in Colorectal Cancer by Lausten, Molly A, Boman, Bruce M

“…As advancements in sequencing technology rapidly continue to develop, a new classification of microRNAs has occurred with the discovery of isomiRs, which are…”
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Autocatalytic Tissue Polymerization Reaction Mechanism in Colorectal Cancer Development and Growth by Boman, Bruce M, Guetter, Arthur, Boman, Ryan M, Runquist, Olaf A

“…The goal of our study was to measure the kinetics of human colorectal cancer (CRC) development in order to identify aberrant mechanisms in tissue dynamics and…”
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AI-driven adaptive treatment strategies in internet-delivered CBT by Kaldo, V., Isacsson, N., Forsell, E., Bjurner, P., Abdesslem, F. Ben, Boman, M.

“…Introduction: Adaptive Treatment Strategies warns therapists of patients at risk of treatment failure to prompt an adaption of the intervention…”
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