Search Results - "Bolzoni, Marina"

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target by Bolzoni, Marina, Chiu, Martina, Accardi, Fabrizio, Vescovini, Rosanna, Airoldi, Irma, Storti, Paola, Todoerti, Katia, Agnelli, Luca, Missale, Gabriele, Andreoli, Roberta, Bianchi, Massimiliano G., Allegri, Manfredi, Barilli, Amelia, Nicolini, Francesco, Cavalli, Albertina, Costa, Federica, Marchica, Valentina, Toscani, Denise, Mancini, Cristina, Martella, Eugenia, Dall'Asta, Valeria, Donofrio, Gaetano, Aversa, Franco, Bussolati, Ovidio, Giuliani, Nicola

“…The importance of glutamine (Gln) metabolism in multiple myeloma (MM) cells and its potential role as a therapeutic target are still unknown, although it has…”
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Mechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone Remodeling by Aversa, Franco, Dalla Palma, Benedetta, Bolzoni, Marina, Toscani, Denise, Accardi, Fabrizio, Giuliani, Nicola

“…Multiple myeloma (MM) is characterized by a high capacity to induce alterations in the bone remodeling process. The increase in osteoclastogenesis and the…”
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The Proteasome Inhibitor Bortezomib Maintains Osteocyte Viability in Multiple Myeloma Patients by Reducing Both Apoptosis and Autophagy: A New Function for Proteasome Inhibitors by Toscani, Denise, Palumbo, Carla, Dalla Palma, Benedetta, Ferretti, Marzia, Bolzoni, Marina, Marchica, Valentina, Sena, Paola, Martella, Eugenia, Mancini, Cristina, Ferri, Valentina, Costa, Federica, Accardi, Fabrizio, Craviotto, Luisa, Aversa, Franco, Giuliani, Nicola

“…ABSTRACT Multiple myeloma (MM) is characterized by severely imbalanced bone remodeling. In this study, we investigated the potential effect of proteasome…”
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Assessing satisfaction in simulation among nursing students: psychometric properties of the Satisfaction with Simulation Experience - Italian Version scale by Alberti, Sara, Guasconi, Massimo, Bolzoni, Marina, Donnini, Giulia, Volpi, Paola, Rovesti, Sergio, Monaco, Federico, Bonacaro, Antonio, Ferri, Paola

“…The Satisfaction with Simulation Experience scale is a 5-point Likert scale that measures students' satisfaction in medium and high-fidelity simulation…”
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IL21R expressing CD14 + CD16 + monocytes expand in multiple myeloma patients leading to increased osteoclasts by Bolzoni, Marina, Ronchetti, Domenica, Storti, Paola, Donofrio, Gaetano, Marchica, Valentina, Costa, Federica, Agnelli, Luca, Toscani, Denise, Vescovini, Rosanna, Todoerti, Katia, Bonomini, Sabrina, Sammarelli, Gabriella, Vecchi, Andrea, Guasco, Daniela, Accardi, Fabrizio, Palma, Benedetta Dalla, Gamberi, Barbara, Ferrari, Carlo, Neri, Antonino, Aversa, Franco, Giuliani, Nicola

“…Bone marrow monocytes are primarily committed to osteoclast formation. It is, however, unknown whether potential primary alterations are specifically present…”
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Role of Osteocytes in Myeloma Bone Disease: Anti-sclerostin Antibody as New Therapeutic Strategy by Toscani, Denise, Bolzoni, Marina, Ferretti, Marzia, Palumbo, Carla, Giuliani, Nicola

“…Osteocytes are terminally differentiated cells of the osteoblast lineage. They are involved in the regulation of bone remodeling by increasing osteoclast…”
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NAD⁺-Metabolizing Ectoenzymes in Remodeling Tumor-Host Interactions: The Human Myeloma Model by Horenstein, Alberto L, Chillemi, Antonella, Quarona, Valeria, Zito, Andrea, Roato, Ilaria, Morandi, Fabio, Marimpietri, Danilo, Bolzoni, Marina, Toscani, Denise, Oldham, Robert J, Cuccioloni, Massimiliano, Sasser, A Kate, Pistoia, Vito, Giuliani, Nicola, Malavasi, Fabio

“…Nicotinamide adenine dinucleotide (NAD⁺) is an essential co-enzyme reported to operate both intra- and extracellularly. In the extracellular space, NAD⁺ can…”
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New Insights into Osteogenic and Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells and Their Potential Clinical Applications for Bone Regeneration in Pediatric Orthopaedics by Lisignoli, Gina, Giuliani, Nicola, Magnani, Marina, Racano, Costantina, Bolzoni, Marina, Dalla Palma, Benedetta, Spolzino, Angelica, Manferdini, Cristina, Abati, Caterina, Toscani, Denise, Facchini, Andrea, Aversa, Franco

“…Human mesenchymal stem cells (hMSCs) are pluripotent adult stem cells capable of being differentiated into osteoblasts, adipocytes, and chondrocytes. The…”
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The anti-tumoral effect of lenalidomide is increased in vivo by hypoxia-inducible factor (HIF)-1α inhibition in myeloma cells by Storti, Paola, Toscani, Denise, Airoldi, Irma, Marchica, Valentina, Maiga, Sophie, Bolzoni, Marina, Fiorini, Elena, Campanini, Nicoletta, Martella, Eugenia, Mancini, Cristina, Guasco, Daniela, Ferri, Valentina, Donofrio, Gaetano, Aversa, Franco, Amiot, Martine, Giuliani, Nicola

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Cutaneous localization in multiple myeloma in the context of bortezomib-based treatment: how do myeloma cells escape from the bone marrow to the skin? by Marchica, Valentina, Accardi, Fabrizio, Storti, Paola, Mancini, Cristina, Martella, Eugenia, Dalla Palma, Benedetta, Bolzoni, Marina, Todoerti, Katia, Marcatti, Magda, Schifano, Chiara, Bonomini, Sabrina, Sammarelli, Gabriella, Neri, Antonino, Ponzoni, Maurilio, Aversa, Franco, Giuliani, Nicola

“…The skin is a possible site of extramedullary localization in multiple myeloma (MM) patients; however, the mechanisms involved in this process are poorly…”
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Lenalidomide increases human dendritic cell maturation in multiple myeloma patients targeting monocyte differentiation and modulating mesenchymal stromal cell inhibitory properties by Costa, Federica, Vescovini, Rosanna, Bolzoni, Marina, Marchica, Valentina, Storti, Paola, Toscani, Denise, Accardi, Fabrizio, Notarfranchi, Laura, Dalla Palma, Benedetta, Manferdini, Cristina, Manni, Sabrina, Todaro, Giannalisa, Lisignoli, Gina, Piazza, Francesco, Aversa, Franco, Giuliani, Nicola

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The osteoblastic niche in the context of multiple myeloma by Toscani, Denise, Bolzoni, Marina, Accardi, Fabrizio, Aversa, Franco, Giuliani, Nicola

“…The osteoblastic niche has a critical role in the regulation of hemopoietic stem cell (HSC) quiescence and self‐renewal and in the support of hematopoiesis…”
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The link between bone microenvironment and immune cells in multiple myeloma: Emerging role of CD38 by Bolzoni, Marina, Toscani, Denise, Costa, Federica, Vicario, Emanuela, Aversa, Franco, Giuliani, Nicola

“…•Increased osteoclasts (OCLs) characterize multiple myeloma (MM) microenvironment.•OCLs support the survival of MM cells and protect them from T cell…”
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Immunomodulatory drugs lenalidomide and pomalidomide inhibit multiple myeloma-induced osteoclast formation and the RANKL/OPG ratio in the myeloma microenvironment targeting the expression of adhesion molecules by Bolzoni, Marina, Storti, Paola, Bonomini, Sabrina, Todoerti, Katia, Guasco, Daniela, Toscani, Denise, Agnelli, Luca, Neri, Antonino, Rizzoli, Vittorio, Giuliani, Nicola

“…Multiple myeloma (MM)–induced osteoclast (OC) formation is mainly due to an imbalance of the receptor activator NF-κB ligand (RANKL)–osteoprotegerin (OPG)…”
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Expression of CD38 in myeloma bone niche: A rational basis for the use of anti-CD38 immunotherapy to inhibit osteoclast formation by Costa, Federica, Toscani, Denise, Chillemi, Antonella, Quarona, Valeria, Bolzoni, Marina, Marchica, Valentina, Vescovini, Rosanna, Mancini, Cristina, Martella, Eugenia, Campanini, Nicoletta, Schifano, Chiara, Bonomini, Sabrina, Accardi, Fabrizio, Horenstein, Alberto L, Aversa, Franco, Malavasi, Fabio, Giuliani, Nicola

“…It is known that multiple myeloma (MM) cells express CD38 and that a recently developed human anti-CD38 monoclonal antibody Daratumumab mediates myeloma…”
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Unraveling the contribution of ectoenzymes to myeloma life and survival in the bone marrow niche by Quarona, Valeria, Ferri, Valentina, Chillemi, Antonella, Bolzoni, Marina, Mancini, Cristina, Zaccarello, Gianluca, Roato, Ilaria, Morandi, Fabio, Marimpietri, Danilo, Faccani, Giuliano, Martella, Eugenia, Pistoia, Vito, Giuliani, Nicola, Horenstein, Alberto L., Malavasi, Fabio

“…The bone marrow provides a protected environment for generating a vast array of cell types. Bones are thus a dynamic source of structural components and…”
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Randomised controlled prospective study of the use of adhesive elastic tape for the control of hand oedema in patients with a wrist fracture treated in a cast: a study protocol by Guasconi, Massimo, Riboni, Dania Zilli, Granata, Carlotta, Bolzoni, Marina, Beretta, Maurizio, Mozzarelli, Fabio, Maniscalco, Pietro

“…Wrist fractures are a common occurrence, affecting patients of all ages. Wrist fracture patients often develop oedema and the presence of a cast increases the…”
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Assessment and pain management during the triage phase of children with extremity trauma. A retrospective analysis in a Pediatric Emergency Room after the introduction of the PIPER recommendations by Granata, Carlotta, Guasconi, Massimo, Ruggeri, Francesca, Bolzoni, Marina, Grossi, Cinzia Franca, Biasucci, Giacomo, Cella, Andrea

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The use of adhesive elastic tape for hand oedema control in patients with a wrist fracture treated in a cast: A pilot study by Guasconi, Massimo, Zilli Riboni, Dania, Civardi, Andrea, Bolzoni, Marina, Granata, Carlotta, Beretta, Maurizio, Genovese, Anna, Mozzarelli, Fabio, Quattrini, Fabrizio, Maniscalco, Pietro

“…The adhesive elastic tape use is indicated for controlling oedema, although currently there is not the definitive evidence regarding its effectiveness. Wrist…”
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Angiogenesis and Multiple Myeloma by Giuliani, Nicola, Storti, Paola, Bolzoni, Marina, Palma, Benedetta Dalla, Bonomini, Sabrina

“…The bone marrow microenvironment in multiple myeloma is characterized by an increased microvessel density. The production of pro-angiogenic molecules is…”
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