Search Results - "Bolze, S"
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Akkermansia muciniphila phospholipid induces homeostatic immune responses
Published in Nature (London) (04-08-2022)“…Multiple studies have established associations between human gut bacteria and host physiology, but determining the molecular mechanisms underlying these…”
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Imeglimin increases glucose-dependent insulin secretion and improves β-cell function in patients with type 2 diabetes
Published in Diabetes, obesity & metabolism (01-06-2015)“…Aims To assess the glucose‐stimulated insulin secretion effect of imeglimin in patients with type 2 diabetes. Methods We conducted a double‐blind, randomized,…”
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3
Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration
Published in Cell death discovery (01-01-2016)“…Imeglimin is the first in a new class of oral glucose-lowering agents, having recently completed its phase 2b trial. As Imeglimin did show a full prevention of…”
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Mechanisms of Ligand-Protein Interaction in Sec-14-like Transporters Investigated by Computer Simulations
Published in Chimia (01-09-2014)“…We review our recent work on protein-ligand interactions in vitamin transporters of the Sec-14-like protein. Our studies focused on the cellular-retinaldehyde…”
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5
Collinsella aerofaciens Produces a pH-Responsive Lipid Immunogen
Published in Journal of the American Chemical Society (05-04-2023)“…Some members of the human gut microbiota profoundly influence their host’s physiology, health, and therapeutic responses, but the responsible molecules and…”
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6
Physical inactivity and knee osteoarthritis in guinea pigs
Published in Osteoarthritis and cartilage (01-11-2019)“…To investigate whether and how a sedentary lifestyle contributes to knee osteoarthritis (OA) incidence and severity. An experiment was conducted using Hartley…”
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Cellular Retinaldehyde Binding ProteinDifferent Binding Modes and Micro-Solvation Patterns for High-Affinity 9-cis- and 11-cis-Retinal Substrates
Published in The journal of physical chemistry. B (19-09-2013)“…We use molecular dynamics (MD) simulations to determine the binding properties of different retinoid species to cellular retinaldehyde binding protein…”
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Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-cis-Retinal Isomerase Activity
Published in Journal of the American Chemical Society (08-01-2014)“…Cellular retinaldehyde-binding protein (CRALBP) chaperones 11-cis-retinal to convert opsin receptor molecules into photosensitive retinoid pigments of the eye…”
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10
Michael White: marcos teóricos da Prática Narrativa
Published in Fractal : revista de psicologia (2022)“…Post-modernity, narrative turn, constructivist and constructionist paradigms have opened various perspectives for the psychotherapeutic intervention. This…”
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P577Short- and long-term imeglimin treatment reduces metabolic syndrome-related diabetic cardiomyopathy
Published in European heart journal (01-08-2017)Get full text
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P2500Acute imeglimin treatment improves metabolic syndrome-related cardiac and coronary endothelial dysfunction in the zucker fa/fa rat
Published in European heart journal (01-08-2018)Get full text
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Imeglimin increases glucose-dependent insulin secretion and improves [beta]-cell function in patients with type 2 diabetes
Published in Diabetes, obesity & metabolism (01-06-2015)“…Aims To assess the glucose-stimulated insulin secretion effect of imeglimin in patients with type 2 diabetes. Methods We conducted a double-blind, randomized,…”
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Journal Article -
14
Influence of zinc on growth, somatomedin, and glycosaminoglycan metabolism in rats
Published in The American journal of physiology (01-01-1987)“…Weanling male rats were fed control ad libitum, zinc-deficient (ZD, 1 ppm zinc) or pair-fed (PF) control diets for 13 days. Rats subsequently were refed…”
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15
Density-Based Spectral Analysis of a Turbulent Compression Ramp Shock Boundary Layer Interaction at Mach 2.3
Published 01-01-2024“…Quantitative high-speed schlieren imaging and various spectral analysis techniques are employed to characterize low-frequency unsteadiness observed in an…”
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Dissertation -
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Development of an in Vitro Screening Model for the Biosynthesis of Acyl Glucuronide Metabolites and the Assessment of Their Reactivity toward Human Serum Albumin
Published in Drug metabolism and disposition (01-04-2002)“…An in vitro screening model was developed to determine the reactivity of acyl glucuronide metabolites from carboxylic drugs. This assay is composed of two…”
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Taste acuity, plasma zinc levels, and weight loss during radiotherapy: a study of relationships
Published in Radiology (01-07-1982)“…Thirty-five patients who were to undergo radiotherapy and 13 normal subjects were evaluated with taste questionnaires, taste acuity tests, and plasma zinc…”
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Influence of selected amino acid deficiencies on somatomedin, growth and glycosaminoglycan metabolism in weanling rats
Published in The Journal of nutrition (01-06-1985)“…The effects of lysine-, methionine- or histidine-deficient diets compared to a control diet fed ad libitum or 15, 10 or 5 g/d were studied in weanling rats…”
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HPLC determination of ketamine, norketamine, and dehydronorketamine in plasma with a high-purity reversed-phase sorbent
Published in Clinical chemistry (Baltimore, Md.) (01-03-1998)“…We developed an isocratic, selective, and very sensitive HPLC method for the determination of ketamine and its two main metabolites in plasma. The compounds…”
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Gender differences in the responses of serum insulin-like growth factor-1 and transthyretin (prealbumin) to trauma
Published in Critical care medicine (01-12-1996)“…OBJECTIVETo determine whether factors such as age, gender, and severity of injury should be considered when evaluating serum insulin-like growth factor (IGF)-1…”
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