Search Results - "Bolzani, Vanderlan"
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The potential contribution of the natural products from Brazilian biodiversity to bioeconomy
Published in Anais da Academia Brasileira de Ciências (01-01-2018)“…The development of our society has been based on the use of biodiversity, especially for medicines and nutrition. Brazil is the nation with the largest…”
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Reaction of the Phytochemistry Community to Green Chemistry: Insights Obtained Since 1990
Published in Journal of natural products (Washington, D.C.) (24-02-2023)“…This review article aims to study how phytochemists have reacted to green chemistry insights since 1990, the year when the U.S. Environmental Protection Agency…”
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Natural Products: Perspectives and Challenges for use of Brazilian Plant Species in the Bioeconomy
Published in Anais da Academia Brasileira de Ciências (01-01-2019)“…The development of our society has been based on the use of biodiversity, especially for nutrition, medicines and beauty. Brazil is the nation with the largest…”
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Natural deep eutectic solvents as the major mobile phase components in high-performance liquid chromatography—searching for alternatives to organic solvents
Published in Analytical and bioanalytical chemistry (01-06-2018)“…Over the past six decades, acetonitrile (ACN) has been the most employed organic modifier in reversed-phase high-performance liquid chromatography (RP-HPLC),…”
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NuBBEDB: an updated database to uncover chemical and biological information from Brazilian biodiversity
Published in Scientific reports (03-08-2017)“…The intrinsic value of biodiversity extends beyond species diversity, genetic heritage, ecosystem variability and ecological services, such as climate…”
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Mass Spectral Similarity Networking and Gas-Phase Fragmentation Reactions in the Structural Analysis of Flavonoid Glycoconjugates
Published in Analytical chemistry (Washington) (20-08-2019)“…Flavonoids represent an important class of natural products with a central role in plant physiology and human health. Their accurate annotation using…”
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Recent advances in the use of vibrational chiroptical spectroscopic methods for stereochemical characterization of natural products
Published in Natural product reports (01-01-2015)“…This review covers conformational and configurational assignments in natural product molecules using chiroptical spectroscopy reported over the last 15 years…”
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Homology Modeling of Alpha-Glucosidase from Candida albicans: Sequence Analysis and Structural Validation Studies in silico
Published in Journal of the Brazilian Chemical Society (2024)“…The alpha-glucosidase enzyme of Candida albicans plays a vital role in the pathogenesis of candidiasis, a serious fatal disease in immune-compromised patients…”
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Molecular hybridization: a useful tool in the design of new drug prototypes
Published in Current medicinal chemistry (01-07-2007)“…Molecular hybridization is a new concept in drug design and development based on the combination of pharmacophoric moieties of different bioactive substances…”
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Crotalaria spectabilis as a source of pyrrolizidine alkaloids and phenolic compounds: HPLC‐MS/MS dereplication and monocrotaline quantification of seed and leaf extracts
Published in Phytochemical analysis (01-11-2020)“…Introduction Crotalaria spectabilis is an important species used as a pre‐plant cover for soybean crops to control the proliferation of endoparasitic…”
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Sustainable and Biomimetic Methodology for Extraction of High-Value-Added Compounds in Almond Hulls
Published in Molecules (Basel, Switzerland) (26-06-2024)“…Almond trees are the most cultivated nut tree in the world. The production of almonds generates large amounts of by-products, much of which goes unused…”
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Development of a Natural Products Database from the Biodiversity of Brazil
Published in Journal of natural products (Washington, D.C.) (22-03-2013)“…We describe herein the design and development of an innovative tool called the NuBBE database (NuBBEDB), a new Web-based database, which incorporates several…”
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Identification of natural cytochalasins as leads for neglected tropical diseases drug discovery
Published in PloS one (03-10-2022)“…Investigating the chemical diversity of natural products from tropical environments is an inspiring approach to developing new drug candidates for neglected…”
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Redox-active biflavonoids from Garcinia brasiliensis as inhibitors of neutrophil oxidative burst and human erythrocyte membrane damage
Published in Journal of ethnopharmacology (04-11-2015)“…Garcinia brasiliensis, a plant native to the Brazilian Amazon Rainforest, is used in traditional medicine to treat inflammation of the urinary tract, peptic…”
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15
Discovery of a Beetroot Protease Inhibitor to Identify and Classify Plant-Derived Cystine Knot Peptides
Published in Journal of natural products (Washington, D.C.) (25-11-2020)“…Plant peptide protease inhibitors are important molecules in seed storage metabolism and to fight insect pests. Commonly they contain multiple disulfide bonds…”
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Advanced Glycation End Product Inhibition by Alkaloids from Ocotea paranapiacabensis for the Prevention of Skin Aging
Published in Journal of natural products (Washington, D.C.) (27-03-2020)“…A bioassay-guided study aiming at identifying inhibitors of the glycation process on the leaves of Ocotea paranapiacabensis afforded four benzylisoquinoline…”
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Natural deep eutectic solvents and aqueous solutions as an alternative extraction media for propolis
Published in Food research international (01-11-2019)“…Ethanolic extracts of propolis are consumed for their health benefits even though direct consumption of alcoholic extracts is not always ideal. Natural Deep…”
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Old Meets New: Mass Spectrometry-Based Untargeted Metabolomics Reveals Unusual Larvicidal Nitropropanoyl Glycosides from the Leaves of Heteropterys umbellata
Published in Journal of natural products (Washington, D.C.) (24-03-2023)“…The Aedes aegypti (Diptera: Culicidae) mosquito is the vector of several arboviruses in tropical and subtropical areas of the globe, and synthetic pesticides…”
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Chemical Space and Diversity of the NuBBE Database: A Chemoinformatic Characterization
Published in Journal of chemical information and modeling (28-01-2019)“…NuBBEDB is the first library of natural products of Brazilian biodiversity. It includes a large variety of classes of compounds and structural types of…”
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Can Statistical Evaluation Tools for Chromatographic Method Development Assist in the Natural Products Workflow? A Case Study on Selected Species of the Plant Family Malpighiaceae
Published in Journal of natural products (Washington, D.C.) (25-11-2020)“…Proper chromatographic methods may reduce the challenges inherent in analyzing natural product extracts, especially when utilizing hyphenated detection…”
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