Relationship between concurrent substance abuse in psychiatric patients and neuroleptic dosage

The use of a structured diagnostic interview (The Schedule for Affective Disorders and Schizophrenia) with 58 consecutively admitted general adult psychiatric patients revealed that 62.1% of them abused alcohol and 58.6% had a substance use disorder. The drug abusers did not differ significantly fro...

Full description

Saved in:

Bibliographic Details
Published in:	The American journal of drug and alcohol abuse Vol. 21; no. 2; p. 257
Main Authors:	D'Mello, D A, Boltz, M K, Msibi, B
Format:	Journal Article
Language:	English
Published:	England 01-01-1995
Subjects:	Adolescent Adult Age Factors Aged Chlorpromazine - administration & dosage Chlorpromazine - therapeutic use Cohort Studies Dose-Response Relationship, Drug Ethanol Female Humans Male Mental Disorders - complications Mental Disorders - drug therapy Middle Aged Narcotics Substance-Related Disorders - complications
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The use of a structured diagnostic interview (The Schedule for Affective Disorders and Schizophrenia) with 58 consecutively admitted general adult psychiatric patients revealed that 62.1% of them abused alcohol and 58.6% had a substance use disorder. The drug abusers did not differ significantly from the nonabusers on mean psychoticism (Brief Psychiatric Rating Scale) scores. However, they received higher doses of antipsychotic agents (mean daily dose 1022 mg CPZ EQ (SD = 614) vs 609 mg CPZ EQ (SD = 481); z = 2.58, p < .01) to achieve stabilization. The clinical implications of this finding are discussed.
ISSN:	0095-2990
DOI:	10.3109/00952999509002693