Fertility alpha-2-microglobulin expression in the human bulbourethral glands

Fertility alpha-2-microglobulin (FAMG) was demonstrated in the human bulbourethral glands by the method of indirect immunoperoxidase staining using monoclonal antibodies against FAMG. The product of the immunohistochemical reaction was primary found in the duct cells. Weak immunopositive reaction wa...

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Bibliographic Details
Published in:	Morfologiia (Saint Petersburg, Russia) Vol. 125; no. 2; p. 76
Main Authors:	Boronikhina, T V, Starosvetskaia, N A, Boltovskaia, M H, Iatskovskiĭ, A N
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 2004
Subjects:	Bulbourethral Glands - cytology Bulbourethral Glands - metabolism Glycodelin Glycoproteins - metabolism Humans Immunohistochemistry Male Pregnancy Proteins - metabolism Secretory Vesicles - metabolism
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Summary:	Fertility alpha-2-microglobulin (FAMG) was demonstrated in the human bulbourethral glands by the method of indirect immunoperoxidase staining using monoclonal antibodies against FAMG. The product of the immunohistochemical reaction was primary found in the duct cells. Weak immunopositive reaction was observed in single epitheliocytes of the secretory units. FAMG-positive granularity was typically found in the supranuclear cytoplasmic zone, that corresponds to the localization of secretory granules both in the glandulocytes and in the duct cells. These results suggest, that the bulbourethral glands are probably the additional producers of human seminal plasma FAMG.
ISSN:	1026-3543