Search Results - "Bolteau, Raphaël"

Structure–Activity Relationship of Inositol Thiophosphate Analogs as Allosteric Activators of Clostridioides difficile Toxin B by Cummer, Rebecca, Grosjean, Félix, Bolteau, Raphaël, Vasegh, Seyed Ehsan, Veyron, Simon, Keogh, Liam, Trempe, Jean-François, Castagner, Bastien

“…Clostridioides difficile is a bacterium that causes life-threatening intestinal infections. Infection symptoms are mediated by a toxin secreted by the…”
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Novel Quinazoline Derivatives as Highly Effective A2A Adenosine Receptor Antagonists by Laversin, Amélie, Dufossez, Robin, Bolteau, Raphaël, Duroux, Romain, Ravez, Séverine, Hernandez-Tapia, Sergio, Fossart, Martin, Coevoet, Mathilde, Liberelle, Maxime, Yous, Saïd, Lebègue, Nicolas, Melnyk, Patricia

“…The adenosine A receptor (A R) has been identified as a therapeutic target for treating neurodegenerative diseases and cancer. In recent years, we have…”
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High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists by Bolteau, Raphaël, Duroux, Romain, Laversin, Amélie, Vreulz, Brandon, Shiriaeva, Anna, Stauch, Benjamin, Han, Gye Won, Cherezov, Vadim, Renault, Nicolas, Barczyk, Amélie, Ravez, Séverine, Coevoet, Mathilde, Melnyk, Patricia, Liberelle, Maxime, Yous, Saïd

“…The past fifty years have been marked by the surge of neurodegenerative diseases. Unfortunately, current treatments are only symptomatic. Hence, the search for…”
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Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine by Bolteau, Raphaël, Descamps, Florian, Ettaoussi, Mohamed, Caignard, Daniel H., Delagrange, Philippe, Melnyk, Patricia, Yous, Saïd

“…For further development of successors of Agomelatine through modulation of its pharmacokinetic properties, we report herein the design, synthesis and…”
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Design and synthesis of 2,6-disubstituted-8-amino imidazo[1,2a]pyridines, a promising privileged structure by Boulahjar, Rajaa, Rincon Arias, Angela, Bolteau, Raphaël, Renault, Nicolas, Coevoet, Mathilde, Barczyk, Amélie, Duroux, Romain, Yous, Saïd, Melnyk, Patricia, Agouridas, Laurence

“…[Display omitted] Imidazo[1,2a]pyridines have gained much interest in the field of medicinal chemistry research. In the aim of accessing new privileged…”
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