Search Results - "Bolster, Douglas R."

Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle by Bolster, Douglas R., Kubica, Neil, Crozier, Stephen J., Williamson, David L., Farrell, Peter A., Kimball, Scot R., Jefferson, Leonard S.

“…The purpose of the present investigation was to determine whether mammalian target of rapamycin (mTOR)-mediated signalling and some key regulatory proteins of…”
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Leucine, Not Total Protein, Content of a Supplement Is the Primary Determinant of Muscle Protein Anabolic Responses in Healthy Older Women by Devries, Michaela C, McGlory, Chris, Bolster, Douglas R, Kamil, Alison, Rahn, Maike, Harkness, Laura, Baker, Steven K, Phillips, Stuart M

“…Older adults show a blunted muscle protein synthesis (MPS) response to postprandial hyperaminoacidemia relative to younger adults. Evidence suggests that this…”
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AMP-activated Protein Kinase Suppresses Protein Synthesis in Rat Skeletal Muscle through Down-regulated Mammalian Target of Rapamycin (mTOR) Signaling by Bolster, Douglas R., Crozier, Stephen J., Kimball, Scot R., Jefferson, Leonard S.

“…AMP-activated protein kinase (AMPK) is viewed as an energy sensor that acts to modulate glucose uptake and fatty acid oxidation in skeletal muscle. Given that…”
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Repression of protein synthesis and mTOR signaling in rat liver mediated by the AMPK activator aminoimidazole carboxamide ribonucleoside by Reiter, Ali K, Bolster, Douglas R, Crozier, Stephen J, Kimball, Scot R, Jefferson, Leonard S

“…The studies described herein were designed to investigate the effects of 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside (AICAR), an activator of the…”
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Protein leucine content is a determinant of shorter- and longer-term muscle protein synthetic responses at rest and following resistance exercise in healthy older women: a randomized, controlled trial by Devries, Michaela C, McGlory, Christopher, Bolster, Douglas R, Kamil, Alison, Rahn, Maike, Harkness, Laura, Baker, Steven K, Phillips, Stuart M

“…Older women may not be consuming enough protein to maintain muscle mass. Augmentation of protein intake with leucine may enhance the muscle protein synthetic…”
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Dietary protein intake impacts human skeletal muscle protein fractional synthetic rates after endurance exercise by Bolster, Douglas R, Pikosky, Matthew A, Gaine, P Courtney, Martin, William, Wolfe, Robert R, Tipton, Kevin D, Maclean, David, Maresh, Carl M, Rodriguez, Nancy R

“…This investigation evaluated the physiological impact of different dietary protein intakes on skeletal muscle protein synthesis postexercise in endurance…”
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Differential Responses of Blood Essential Amino Acid Levels Following Ingestion of High-Quality Plant-Based Protein Blends Compared to Whey Protein-A Double-Blind Randomized, Cross-Over, Clinical Trial by Brennan, Jessica L, Keerati-U-Rai, Maneephan, Yin, Huaixia, Daoust, Julie, Nonnotte, Emilie, Quinquis, Laurent, St-Denis, Thierry, Bolster, Douglas R

“…This study assessed the bio-equivalence of high-quality, plant-based protein blends versus Whey Protein Isolate (WPI) in healthy, resistance-trained men. The…”
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Level of dietary protein impacts whole body protein turnover in trained males at rest by Gaine, Patricia C., Pikosky, Matthew A., Martin, William F., Bolster, Douglas R., Maresh, Carl M., Rodriguez, Nancy R.

“…The current investigation examined the effect of variations in protein intake on Whole body protein turnover (WBPTO) at rest in endurance-trained males. Whole…”
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Postexercise whole-body protein turnover response to three levels of protein intake by GAINE, Patricia Courtney, PIKOSKY, Matthew A, BOLSTER, Douglas R, MARTIN, William F, MARESH, Carl M, RODRIGUEZ, Nancy R

“…This investigation examined the effect of variations in protein intake on whole-body protein turnover (WBPTO) after exercise in endurance-trained males. Five…”
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Translational control mechanisms modulate skeletal muscle gene expression during hypertrophy by Bolster, Douglas R, Kimball, Scot R, Jefferson, Leonard S

“…Understanding the basic mechanisms regulating skeletal muscle hypertrophy is essential to providing strategies for optimizing and maintaining skeletal muscle…”
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Daily intake of dairy products in Brazil and contributions to nutrient intakes: a cross-sectional study by Murphy, Mary M, Barraj, Leila M, Toth, Lindsey D, Harkness, Laura S, Bolster, Douglas R

“…Dairy products are sources of protein and micronutrients important in a healthy diet. The purpose of the present analysis was to estimate consumption of dairy…”
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Consuming Lower-Protein Nutrition Bars with Added Leucine Elicits Postprandial Changes in Appetite Sensations in Healthy Women by Bolster, Douglas R, Rahn, Maike, Kamil, Alison G, Bristol, Lindsey T, Goltz, Shellen R, Leidy, Heather J, Blaze Mt, Melvin, Nunez, Michael A, Guo, Elizabeth, Wang, Jianquan, Harkness, Laura S

“…Higher-protein meals (>25 g protein/meal) have been associated with enhanced satiety but the role of amino acids is unclear. Leucine has been proposed to…”
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Level of dietary protein intake affects glucose turnover in endurance-trained men by Pasiakos, Stefan M, Martin, William F, Sharma, Charu S, Pikosky, Matthew A, Gaine, Patricia C, Bolster, Douglas R, Bennett, Brian T, Rodriguez, Nancy R

“…To examine the effects of higher-protein diets on endogenous glucose metabolism in healthy, physically active adults, glucose turnover was assessed in five…”
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Resistance Exercise Increases Muscle Protein Synthesis and Translation of Eukaryotic Initiation Factor 2Bϵ mRNA in a Mammalian Target of Rapamycin-dependent Manner by Kubica, Neil, Bolster, Douglas R., Farrell, Peter A., Kimball, Scot R., Jefferson, Leonard S.

“…The contribution of mammalian target of rapamycin (mTOR) signaling to the resistance exercise-induced stimulation of skeletal muscle protein synthesis was…”
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Time course changes in signaling pathways and protein synthesis in C2C12 myotubes following AMPK activation by AICAR by Williamson, David L, Bolster, Douglas R, Kimball, Scot R, Jefferson, Leonard S

“…The role of the AMP-activated kinase (AMPK) as a metabolic sensor in skeletal muscle has been far better characterized for glucose and fat metabolism than for…”
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Regulation of protein synthesis associated with skeletal muscle hypertrophy by insulin-, amino acid- and exercise-induced signalling by Bolster, Douglas R., Jefferson, Leonard S., Kimball, Scot R.

“…Although insulin, amino acids and exercise individually activate multiple signal transduction pathways in skeletal muscle, one pathway, the…”
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Leucine regulates translation initiation in rat skeletal muscle via enhanced eIF4G phosphorylation by Bolster, Douglas R, Vary, Thomas C, Kimball, Scot R, Jefferson, Leonard S

“…The BCAA, leucine, stimulates protein synthesis in skeletal muscle in part through enhanced initiation of mRNA translation. However, understanding how leucine…”
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AMPK represses TOP mRNA translation but not global protein synthesis in liver by Reiter, Ali K., Bolster, Douglas R., Crozier, Stephen J., Kimball, Scot R., Jefferson, Leonard S.

“…The AMP-activated protein kinase (AMPK) represses signaling through the mammalian target of rapamycin complex 1 (mTORC1). In muscle, repression of mTORC1 leads…”
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Insights into muscle atrophy and recovery pathway based on genetic models by Stein, T Peter, Bolster, Douglas R

“…PURPOSE OF REVIEWMuscle atrophy is a pervasive problem that occurs with disuse, aging, and a myriad of disease conditions. The purposes of this review are to…”
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Beta -oxidation of free fatty acids is required to maintain translational control of protein synthesis in heart by Crozier, Stephen J, Bolster, Douglas R, Reiter, Ali K, Kimball, Scot R, Jefferson, Leonard S

“…The study described herein investigated the role of free fatty acids (FFAs) in the maintenance of protein synthesis in vivo in rat cardiac and skeletal muscle…”
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