Search Results - "Bolscher, Jan G. M."

D-LL-31 enhances biofilm-eradicating effect of currently used antibiotics for chronic rhinosinusitis and its immunomodulatory activity on human lung epithelial cells by Wongkaewkhiaw, Saharut, Taweechaisupapong, Suwimol, Thanaviratananich, Sanguansak, Bolscher, Jan G M, Nazmi, Kamran, Anutrakunchai, Chitchanok, Chareonsudjai, Sorujsiri, Kanthawong, Sakawrat

“…Chronic rhinosinusitis (CRS) is a chronic disease that involves long-term inflammation of the nasal cavity and paranasal sinuses. Bacterial biofilms present on…”
Get full text

Impact of nutritional stress on drug susceptibility and biofilm structures of Burkholderia pseudomallei and Burkholderia thailandensis grown in static and microfluidic systems by Anutrakunchai, Chitchanok, Bolscher, Jan G M, Krom, Bastiaan P, Kanthawong, Sakawrat, Chareonsudjai, Sorujsiri, Taweechaisupapong, Suwimol

“…Burkholderia pseudomallei is the causative agent of melioidosis and regarded as a bioterrorism threat. It can adapt to the nutrient-limited environment as the…”
Get full text

Synergistic effects of LFchimera and antibiotic against planktonic and biofilm form of Aggregatibacter actinomycetemcomitans by Lachica, Marie Rossini Carmela T, Anutrakunchai, Chitchanok, Prajaneh, Saengsome, Nazmi, Kamran, Bolscher, Jan G M, Taweechaisupapong, Suwimol

“…Adjunctive use of antibiotics in periodontal treatment have limitations and disadvantages including bacterial resistance. Antimicrobial peptides (AMPs) are…”
Get full text

Histatins are the major wound-closure stimulating factors in human saliva as identified in a cell culture assay by Oudhoff, Menno J, Bolscher, Jan G.M, Nazmi, Kamran, Kalay, Hakan, van 't Hof, Wim, Amerongen, Arie V. Nieuw, Veerman, Enno C.I

“…Wounds in the oral cavity heal much faster than skin lesions. Among other factors, saliva is generally assumed to be of relevance to this feature. Rodent…”
Get full text

Bactericidal effect of bovine lactoferrin, LFcin, LFampin and LFchimera on antibiotic-resistant Staphylococcus aureus and Escherichia coli by Flores-Villaseñor, Héctor, Canizalez-Román, Adrian, Reyes-Lopez, Magda, Nazmi, Kamram, de la Garza, Mireya, Zazueta-Beltrán, Jorge, León-Sicairos, Nidia, Bolscher, Jan G. M

“…Increased prevalence of antibiotic-resistant bacteria has become a major threat to the health sector worldwide due to their virulence, limited therapeutic…”
Get full text

Antimicrobial Peptide LL-37 Is Both a Substrate of Cathepsins S and K and a Selective Inhibitor of Cathepsin L by Andrault, Pierre-Marie, Samsonov, Sergey A, Weber, Gunther, Coquet, Laurent, Nazmi, Kamran, Bolscher, Jan G. M, Lalmanach, Anne-Christine, Jouenne, Thierry, Brömme, Dieter, Pisabarro, M. Teresa, Lalmanach, Gilles, Lecaille, Fabien

“…Lung cysteine cathepsins B, K, L, and S contribute to physiological and pathological processes including degradation of antimicrobial peptides/proteins (AMPs)…”
Get full text

Killing of Mycobacterium avium by Lactoferricin Peptides: Improved Activity of Arginine- and D-Amino-Acid-Containing Molecules by SILVA, Tânia, MAGALHAES, Bárbara, MAIA, Silvia, GOMES, Paula, NAZMI, Kamran, BOLSCHER, Jan G. M, RODRIGUES, Pedro N, BASTOS, Margarida, GOMES, Maria Salomé

“…Mycobacterium avium causes respiratory disease in susceptible individuals, as well as disseminated infections in immunocompromised hosts, being an important…”
Get full text

Histatin‐1, a histidine‐rich peptide in human saliva, promotes cell‐substrate and cell‐cell adhesion by Dijk, Irene A., Nazmi, Kamran, Bolscher, Jan G. M., Veerman, Enno C. I., Stap, Jan

“…Histatins (Hsts) are histidine‐rich peptides exclusively present in the saliva of higher primates. In this study, we explored the effects of Hsts on…”
Get full text

GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and -activating properties of human salivary histatin 1 by Ma, Dandan, Sun, Wei, Fu, Cuicui, Nazmi, Kamran, Veerman, Enno C. I., Jaspers, Richard T., Bolscher, Jan G. M., Bikker, Floris J., Wu, Gang

“…Human salivary histatin 1 (Hst1) exhibits a series of cell-activating properties, such as promoting cell spreading, migration, and metabolic activity. We…”
Get full text

The Influence of Chronic Wound Extracts on Inflammatory Cytokine and Histatin Stability by Boink, Mireille A, Roffel, Sanne, Nazmi, Kamran, van Montfrans, Catherine, Bolscher, Jan G M, Gefen, Amit, Veerman, Enno C I, Gibbs, Susan

“…Chronic ulcers represent a major health burden in our society. Despite many available therapies, a large number of ulcers do not heal. Protein based therapies…”
Get full text

Human Salivary Micro-RNA in Patients with Parotid Salivary Gland Neoplasms by Matse, Johannes H, Yoshizawa, Janice, Wang, Xiaoyan, Elashoff, David, Bolscher, Jan G M, Veerman, Enno C I, Leemans, C René, Pegtel, D Michiel, Pegtel, Michiel D, Wong, David T W, Bloemena, Elisabeth

“…Currently, clinical examination, ultrasound scanning (with or without fine needle aspiration cytology), preoperative CT-scan and MRI are available for the…”
Get full text

Enhanced leishmanicidal activity of cryptopeptide chimeras from the active N1 domain of bovine lactoferrin by Silva, Tânia, Abengózar, María Ángeles, Fernández-Reyes, María, Andreu, David, Nazmi, Kamran, Bolscher, Jan G. M, Bastos, Margarida, Rivas, Luis

“…Two antimicrobial cryptopeptides from the N1 domain of bovine lactoferrin, lactoferricin (LFcin17–30) and lactoferrampin (LFampin265–284), together with a…”
Get full text

Saliva-Derived Host Defense Peptides Histatin1 and LL-37 Increase Secretion of Antimicrobial Skin and Oral Mucosa Chemokine CCL20 in an IL-1α-Independent Manner by Veerman, Enno C. I., Bolscher, Jan G. M., Nazmi, Kamran, Roffel, Sanne, Boink, Mireille A., Gibbs, Susan

“…Even though skin and oral mucosae are continuously in contact with commensal and opportunistic microorganisms, they generally remain healthy and uninflamed…”
Get full text

Evaluation of salivary mucins in children with deciduous and mixed dentition: comparative analysis between high and low caries-risk groups by Angwaravong, Onauma, Pitiphat, Waranuch, Bolscher, Jan G. M., Chaiyarit, Ponlatham

“…Objectives The aim of this study was to examine levels of salivary mucins in children with deciduous and mixed dentition and to determine correlations between…”
Get full text

Effects of lactoferrin derived peptides on simulants of biological warfare agents by Sijbrandij, Tjitske, Ligtenberg, Antoon J., Nazmi, Kamran, Veerman, Enno C. I., Bolscher, Jan G. M., Bikker, Floris J.

“…Lactoferrin (LF) is an important immune protein in neutrophils and secretory fluids of mammals. Bovine LF (bLF) harbours two antimicrobial stretches,…”
Get full text

Ultrastructural effects and antibiofilm activity of LFchimera against Burkholderia pseudomallei by Puknun, Aekkalak, Kanthawong, Sakawrat, Anutrakunchai, Chitchanok, Nazmi, Kamran, Tigchelaar, Wikky, Hoeben, Kees A, Veerman, Enno C. I, Bolscher, Jan G. M, Taweechaisupapong, Suwimol

“…Lactoferrin chimera (LFchimera), a hybrid peptide containing the two antimicrobial stretches of the innate immunity factor bovine lactoferrin, viz…”
Get full text

Bovine and human lactoferricin peptides: chimeras and new cyclic analogs by Arias, Mauricio, McDonald, Lindsey J., Haney, Evan F., Nazmi, Kamran, Bolscher, Jan G. M., Vogel, Hans J.

“…Lactoferrin (LF) is an important antimicrobial and immune regulatory protein present in neutrophils and most exocrine secretions of mammals. The antimicrobial…”
Get full text

Bactericidal effect of bovine lactoferrin and synthetic peptide lactoferrin chimera in Streptococcus pneumoniae and the decrease in luxS gene expression by lactoferrin by León-Sicairos, Nidia, Angulo-Zamudio, Uriel A., Vidal, Jorge E., López-Torres, Cynthia A., Bolscher, Jan G. M., Nazmi, Kamran, Reyes-Cortes, Ruth, Reyes-López, Magda, de la Garza, Mireya, Canizalez-Román, Adrian

“…Streptococcus pneumoniae (pneumococcus) is responsible for nearly one million child deaths annually. Pneumococcus causes infections such as pneumonia, otitis…”
Get full text

Correction: Human Salivary Micro-RNA in Patients with Parotid Salivary Gland Neoplasms by Matse, Johannes H, Yoshizawa, Janice, Wang, Xiaoyan, Elashoff, David, Bolscher, Jan G M, Veerman, Enno C I, Leemans, C René, Pegtel, D Michiel, Wong, David T W, Bloemena, Elisabeth

“…[This corrects the article DOI: 10.1371/journal.pone.0142264.]…”
Get full text

Lactoferricin Peptides Increase Macrophages' Capacity To Kill Mycobacterium avium by Silva, Tânia, Moreira, Ana C, Nazmi, Kamran, Moniz, Tânia, Vale, Nuno, Rangel, Maria, Gomes, Paula, Bolscher, Jan G M, Rodrigues, Pedro N, Bastos, Margarida, Gomes, Maria Salomé

“…Mycobacterial infections cause a significant burden of disease and death worldwide. Their treatment is long, toxic, costly, and increasingly prone to failure…”
Get full text