Search Results - "Bolotin–Fukuhara, M"
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Thirty years of the HAP2/3/4/5 complex
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-05-2017)“…Thirty years of study of the HAP complex have provided a pretty good picture of the complex components and put forward its original features. The HAP complex…”
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novel Hansenula polymorpha transcriptional factor HpHAP4‐B, able to functionally replace the S. cerevisiae HAP4 gene, contains an additional bZip motif
Published in Yeast (Chichester, England) (01-11-2010)“…The transcriptional regulator HAP4, whose expression is induced on respiratory substrates, has been shown to be involved in the balance between fermentation…”
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The yeast counterparts of human 'MELAS' mutations cause mitochondrial dysfunction that can be rescued by overexpression of the mitochondrial translation factor EF-Tu
Published in EMBO reports (01-01-2003)“…We have taken advantage of the similarity between human and yeast (Saccharomyces cerevisiae) mitochondrial tRNALeu(UUR), and of the possibility of transforming…”
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HAP4, the glucose-repressed regulated subunit of the HAP transcriptional complex involved in the fermentation-respiration shift, has a functional homologue in the respiratory yeast Kluyveromyces lactis
Published in Molecular microbiology (01-02-1999)“…In Saccharomyces cerevisiae, the heteromeric HAP transcription factor is necessary for optimal growth on respiratory carbon sources. One of its components, the…”
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Regulation of primary carbon metabolism in Kluyveromyces lactis
Published in Enzyme and Microbial Technology (01-06-2000)“…In the recent past, through advances in development of genetic tools, the budding yeast Kluyveromyces lactis has become a model system for studies on molecular…”
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Glucose uptake in Kluyveromyces lactis: role of the HGT1 gene in glucose transport
Published in Journal of Bacteriology (01-10-1996)“…A gene for high-affinity glucose transport HGT1, has been isolated from the lactose-assimilating yeast Kluyveromyces lactis. Disruption strains showed…”
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new Hansenula polymorpha HAP4 homologue which contains only the N-terminal conserved domain of the protein is fully functional in Saccharomyces cerevisiae
Published in Current genetics (01-03-2005)“…In Saccharomyces cerevisiae, the HAP transcriptional complex is involved in the fermentation-respiration shift. This complex is composed of four subunits…”
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novel stepwise analysis procedure of genome-wide expression profiles identifies transcript signatures of thiamine genes as classifiers of mitochondrial mutants
Published in Yeast (Chichester, England) (01-02-2008)“…To extract functional information on genes and processes from large expression datasets, analysis methods are required that can computationally deal with these…”
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Reintroduction of a characterized Mit tRNA glycine mutation into yeast mitochondria provides a new tool for the study of human neurodegenerative diseases
Published in Yeast (Chichester, England) (01-02-2001)“…We report the identification and characterization of a new mutation (ts9) in the Saccharomyces cerevisiae mitochondrial genome, which was first genetically…”
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Structure and regulation of SDH3, the yeast gene encoding the cytochrome b560 subunit of respiratory complex II
Published in The Journal of biological chemistry (03-06-1994)“…Using an expression library, we have isolated yeast genes activated in the presence of the yeast CCAAT box-binding protein HAP2. One of these genes, SDH3,…”
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The CCAAT box-binding factor stimulates ammonium assimilation in Saccharomyces cerevisiae, defining a new cross-pathway regulation between nitrogen and carbon metabolisms
Published in Journal of Bacteriology (01-04-1996)“…In Saccharomyces cerevisiae, carbon and nitrogen metabolisms are connected via the incorporation of ammonia into glutamate; this reaction is catalyzed by the…”
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Mutations in yeast mt tRNAs: Specific and general suppression by nuclear encoded tRNA interactors
Published in Gene (01-08-2006)“…Mutations in mitochondrial tRNA genes can produce alterations in tRNA structure resulting in defective mitochondrial protein synthesis and hence respiratory…”
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Mitochondrial chromosome structure: an insight from analysis of complete yeast genomes
Published in FEMS yeast research (01-05-2006)“…Recent progress in the analysis of protein components of the mitochondrial nucleoid and replisome of baker's yeast, Saccharomyces cerevisiae, opens a unique…”
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Mitochondrial effects of the pleiotropic proteasomal mutation mpr1/rpn11: uncoupling from cell cycle defects in extragenic revertants
Published in Gene (06-03-2002)“…We have previously characterized a Saccharomyces cerevisiae mutant which contains a mutation in the essential rpn11/mpr1 gene coding for the proteasomal…”
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The S. cerevisiae HAP complex, a key regulator of mitochondrial function, coordinates nuclear and mitochondrial gene expression
Published in Comparative and functional genomics (01-02-2003)“…We have compared Saccharomyces cerevisiae global gene expression in wild‐type and mutants (Δhap2 and Δhap4) of the HAP transcriptional complex, which has been…”
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Journal Article Conference Proceeding -
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Mutational alterations of translational coupling in the L11 ribosomal protein operon of Escherichia coli
Published in Journal of Bacteriology (01-08-1987)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Additional copies of the mitochondrial Ef-Tu and aspartyl-tRNA synthetase genes can compensate for a mutation affecting the maturation of the mitochondrial tRNA(Asp)
Published in Current genetics (01-06-1997)“…In an attempt to identify new nuclear genes involved in the synthesis and processing of mitochondrial tRNAs, we utilized a multicopy nuclear library to…”
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The respiratory system of Kluyveromyces lactis escapes from HAP2 control
Published in Gene (11-01-1995)“…A functional homolog of the Saccharomyces cerevisiae HAP2 gene, coding for one element of a transcriptional activator complex, was cloned from the yeast…”
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Ts mutations in mitochondrial tRNA genes: characterization and effects of two point mutations in the mitochondrial gene for tRNAphe in Saccharomyces cerevisiae
Published in Current genetics (01-02-1998)“…Two new mitochondrial mutations conferring heat sensitivity on glycerol medium to the cells that carry them and affecting mitochondrial protein synthesis were…”
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The MBR1 gene from Saccharomyces cerevisiae is activated by and required for growth under sub-optimal conditions
Published in Molecular & general genetics (01-07-1997)“…The MBR1 gene was isolated as a multicopy suppressor of the phenotype on glycerol medium of a Saccharomyces cerevisiae strain mutant for the Hap2/3/4/5…”
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