Search Results - "Bolosov, Ilia A."

Mechanism of Action and Therapeutic Potential of the β-Hairpin Antimicrobial Peptide Capitellacin from the Marine Polychaeta Capitella teleta by Safronova, Victoria N, Panteleev, Pavel V, Sukhanov, Stanislav V, Toropygin, Ilia Y, Bolosov, Ilia A, Ovchinnikova, Tatiana V

“…Among the most potent and proteolytically resistant antimicrobial peptides (AMPs) of animal origin are molecules forming a β-hairpin structure stabilized by…”
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Rumicidins are a family of mammalian host-defense peptides plugging the 70S ribosome exit tunnel by Panteleev, Pavel V., Pichkur, Eugene B., Kruglikov, Roman N., Paleskava, Alena, Shulenina, Olga V., Bolosov, Ilia A., Bogdanov, Ivan V., Safronova, Victoria N., Balandin, Sergey V., Marina, Valeriya I., Kombarova, Tatiana I., Korobova, Olga V., Shamova, Olga V., Myasnikov, Alexander G., Borzilov, Alexander I., Osterman, Ilya A., Sergiev, Petr V., Bogdanov, Alexey A., Dontsova, Olga A., Konevega, Andrey L., Ovchinnikova, Tatiana V.

“…The antimicrobial resistance crisis along with challenges of antimicrobial discovery revealed the vital necessity to develop new antibiotics. Many of the…”
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Structure Elucidation and Functional Studies of a Novel β-hairpin Antimicrobial Peptide from the Marine Polychaeta Capitella teleta by Panteleev, Pavel V, Tsarev, Andrey V, Safronova, Victoria N, Reznikova, Olesia V, Bolosov, Ilia A, Sychev, Sergei V, Shenkarev, Zakhar O, Ovchinnikova, Tatiana V

“…Endogenous antimicrobial peptides (AMPs) are evolutionary ancient molecular factors of innate immunity that play a key role in host defense. Among the most…”
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Novel β-Hairpin Peptide from Marine Polychaeta with a High Efficacy against Gram-Negative Pathogens by Safronova, Victoria N., Bolosov, Ilia A., Kruglikov, Roman N., Korobova, Olga V., Pereskokova, Eugenia S., Borzilov, Alexander I., Panteleev, Pavel V., Ovchinnikova, Tatiana V.

“…In recent years, new antibiotics targeting multidrug resistant Gram-negative bacteria have become urgently needed. Therefore, antimicrobial peptides are…”
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Novel BRICHOS-Related Antimicrobial Peptides from the Marine Worm Heteromastus filiformis : Transcriptome Mining, Synthesis, Biological Activities, and Therapeutic Potential by Panteleev, Pavel V, Safronova, Victoria N, Duan, Shuting, Komlev, Alexey S, Bolosov, Ilia A, Kruglikov, Roman N, Kombarova, Tatiana I, Korobova, Olga V, Pereskokova, Eugenia S, Borzilov, Alexander I, Dyachenko, Igor A, Shamova, Olga V, Huang, Yu, Shi, Qiong, Ovchinnikova, Tatiana V

“…Marine polychaetes represent an extremely rich and underexplored source of novel families of antimicrobial peptides (AMPs). The rapid development of next…”
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Combined Antibacterial Effects of Goat Cathelicidins With Different Mechanisms of Action by Panteleev, Pavel V, Bolosov, Ilia A, Kalashnikov, Alexander À, Kokryakov, Vladimir N, Shamova, Olga V, Emelianova, Anna A, Balandin, Sergey V, Ovchinnikova, Tatiana V

“…Being essential components of innate immune system, animal antimicrobial peptides (AMPs) also known as host-defense peptides came into sharp focus as possible…”
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Novel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain by Panteleev, Pavel V, Tsarev, Andrey V, Bolosov, Ilia A, Paramonov, Alexander S, Marggraf, Mariana B, Sychev, Sergey V, Shenkarev, Zakhar O, Ovchinnikova, Tatiana V

“…Endogenous antimicrobial peptides (AMPs) are among the earliest molecular factors in the evolution of animal innate immunity. In this study, novel AMPs named…”
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Dodecapeptide Cathelicidins of Cetartiodactyla: Structure, Mechanism of Antimicrobial Action, and Synergistic Interaction With Other Cathelicidins by Bolosov, Ilia A., Panteleev, Pavel V., Sychev, Sergei V., Sukhanov, Stanislav V., Mironov, Pavel A., Myshkin, Mikhail Yu, Shenkarev, Zakhar O., Ovchinnikova, Tatiana V.

“…In this study, dodecapeptide cathelicidins were shown to be widespread antimicrobial peptides among the Cetruminantia clade. In particular, we investigated the…”
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Cytotoxic Potential of the Novel Horseshoe Crab Peptide Polyphemusin III by Marggraf, Mariana B, Panteleev, Pavel V, Emelianova, Anna A, Sorokin, Maxim I, Bolosov, Ilia A, Buzdin, Anton A, Kuzmin, Denis V, Ovchinnikova, Tatiana V

“…Biological activity of the new antimicrobial peptide polyphemusin III from the horseshoe crab was examined against bacterial strains and human cancer,…”
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Dimerization of the β-Hairpin Membrane-Active Cationic Antimicrobial Peptide Capitellacin from Marine Polychaeta: An NMR Structural and Thermodynamic Study by Mironov, Pavel A, Paramonov, Alexander S, Reznikova, Olesya V, Safronova, Victoria N, Panteleev, Pavel V, Bolosov, Ilia A, Ovchinnikova, Tatiana V, Shenkarev, Zakhar O

“…Capitellacin is the β-hairpin membrane-active cationic antimicrobial peptide from the marine polychaeta . Capitellacin exhibits antibacterial activity,…”
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Design of Protegrin-1 Analogs with Improved Antibacterial Selectivity by Bolosov, Ilia A, Panteleev, Pavel V, Sychev, Sergei V, Khokhlova, Veronika A, Safronova, Victoria N, Toropygin, Ilia Yu, Kombarova, Tatiana I, Korobova, Olga V, Pereskokova, Eugenia S, Borzilov, Alexander I, Ovchinnikova, Tatiana V, Balandin, Sergey V

“…Protegrin-1 (PG-1) is a cationic β-hairpin pore-forming antimicrobial peptide having a membranolytic mechanism of action. It possesses in vitro a potent…”
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Genomic Insights into Bacterial Resistance to Proline-Rich Antimicrobial Peptide Bac7 by Panteleev, Pavel V, Safronova, Victoria N, Kruglikov, Roman N, Bolosov, Ilia A, Ovchinnikova, Tatiana V

“…Proline-rich antimicrobial peptides (PrAMPs) having a potent antimicrobial activity and a modest toxicity toward mammalian cells attract much attention as new…”
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A Novel Proline-Rich Cathelicidin from the Alpaca Vicugna pacos with Potency to Combat Antibiotic-Resistant Bacteria: Mechanism of Action and the Functional Role of the C -Terminal Region by Panteleev, Pavel V, Safronova, Victoria N, Kruglikov, Roman N, Bolosov, Ilia A, Bogdanov, Ivan V, Ovchinnikova, Tatiana V

“…Over recent years, a growing number of bacterial species have become resistant to clinically relevant antibiotics. Proline-rich antimicrobial peptides (PrAMPs)…”
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Design of antimicrobial peptide arenicin analogs with improved therapeutic indices by Panteleev, Pavel V., Bolosov, Ilia A., Balandin, Sergey V., Ovchinnikova, Tatiana V.

“…β‐Hairpin antimicrobial peptides are among the most potent peptide antibiotics of animal origin. Arenicins, isolated earlier from marine polychaeta lugworm…”
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Bioengineering and functional characterization of arenicin shortened analogs with enhanced antibacterial activity and cell selectivity by Panteleev, Pavel V., Bolosov, Ilia A., Ovchinnikova, Tatiana V.

“…New bioengineering approaches are required for development of more active and less toxic antimicrobial peptides. In this study we used β‐hairpin antimicrobial…”
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Discovery of Novel Thanatin-like Antimicrobial Peptides from Bean Bug Riptortus pedestris by Panteleev, Pavel V., Teplovodskaya, Julia S., Utkina, Anastasia D., Smolina, Anastasia A., Kruglikov, Roman N., Safronova, Victoria N., Bolosov, Ilia A., Korobova, Olga V., Borzilov, Alexander I., Ovchinnikova, Tatiana V.

“…Background: Endogenous antimicrobial peptides (AMPs) are evolutionarily ancient molecular factors of innate immunity that play a key role in host defense. The…”
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Design of antimicrobial peptide arenicin analogs with improved therapeutic indices: DESIGN OF ARENICIN ANALOGS WITH IMPROVED THERAPEUTIC INDICES by Panteleev, Pavel V., Bolosov, Ilia A., Balandin, Sergey V., Ovchinnikova, Tatiana V.

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