Search Results - "Bolon, B."

Mouse Models of Rheumatoid Arthritis by Caplazi, P., Baca, M., Barck, K., Carano, R. A. D., DeVoss, J., Lee, W. P., Bolon, B., Diehl, L.

“…Rheumatoid arthritis (RA) is a chronic debilitating autoimmune disorder characterized by synovitis that leads to cartilage and bone erosion by invading…”
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Targeting leukemia stem cells in vivo with antagomiR-126 nanoparticles in acute myeloid leukemia by Dorrance, A M, Neviani, P, Ferenchak, G J, Huang, X, Nicolet, D, Maharry, K S, Ozer, H G, Hoellarbauer, P, Khalife, J, Hill, E B, Yadav, M, Bolon, B N, Lee, R J, Lee, L J, Croce, C M, Garzon, R, Caligiuri, M A, Bloomfield, C D, Marcucci, G

“…Current treatments for acute myeloid leukemia (AML) are designed to target rapidly dividing blast populations with limited success in eradicating the…”
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Generalized Degenerative Joint Disease in Osteoprotegerin (Opg) Null Mutant Mice by Bolon, B., Grisanti, M., Villasenor, K., Morony, S., Feige, U., Simonet, W. S.

“…Bone structure is modulated by the interaction between receptor activator of nuclear factor–κB (RANK) and RANK ligand (RANKL). Osteoprotegerin (OPG), a decoy…”
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Weight of evidence (WOE) and benchmark dose (BMD) analysis: Brain morphometry and startle behavior as examples by Li, A.A, Garman, R.H, Kaufmann, W, Auer, R.N, Bolon, B

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Morphologic Manifestations of Gene-Specific Molecular Alterations (“Genetic Addictions”) in Mouse Models of Disease by Couto, S. S., Bolon, B., Cardiff, R. D.

“…Neoplasia in both animals and humans results in part from lasting activation of tumor-promoting genes (“oncogenes”) or diminished function of genes responsible…”
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Commentary: The Role of the Toxicologic Pathologist in Academia by Turner, P. V., Haschek, W. M., Bolon, B., Diegel, K., Hayes, M. A., McEwen, B., Sargeant, A. M., Scudamore, C. L., Stalker, M., von Beust, B., Wancket, L. M.

“…Veterinary pathologists working as toxicologic pathologists in academic settings fill many vital roles, such as diagnosticians, educators, and/or researchers…”
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Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia by Efanov, A, Zanesi, N, Coppola, V, Nuovo, G, Bolon, B, Wernicle-Jameson, D, Lagana, A, Hansjuerg, A, Pichiorri, F, Croce, C M

“…T-cell acute lymphoblastic leukemia (T-ALL) is a neoplasia of thymocytes characterized by the rapid accumulation of the precursors of T lymphocytes. HMGA2…”
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Internet Resources for Phenotyping Engineered Rodents by Bolon, Brad

“…Genetically engineered mice (GEM) and rats (GER) have emerged as the main mammalian models for investigating normal (physiological, or "health") and abnormal…”
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Internet and Print Resources to Facilitate Pathology Analysis When Phenotyping Genetically Engineered Rodents by Bolon, B., Couto, S., Fiette, L., Perle, K. La

“…Genetically engineered mice and rats are increasingly used as models for exploring disease progression and mechanisms. The full spectrum of anatomic,…”
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Isoflurane leakage from non-rebreathing rodent anaesthesia circuits: comparison of emissions from conventional and modified ports by Smith, J.C, Bolon, B

“…Chronic exposure to low levels of fluorocarbon-based waste anaesthetic gas (WAG) has been linked to a multitude of human health problems. We have shown that…”
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Duration of bone protection by a single osteoprotegerin injection in rats with adjuvant-induced arthritis by Bolon, B, Campagnuolo, G, Feige, U

“…Daily osteoprotegerin (OPG) injection for 7 or more days prevents bone loss for 3 weeks in rats with adjuvant-induced arthritis (AdA). The present experiments…”
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Anti-interleukin-1 and anti-tumor necrosis factor-alpha synergistically inhibit adjuvant arthritis in Lewis rats by Feige, U, Hu, Y L, Gasser, J, Campagnuolo, G, Munyakazi, L, Bolon, B

“…Interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) play dominant roles in mediating the progression of many inflammatory joint diseases,…”
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Neonatal Death in Mice Lacking Cardiotrophin-like Cytokine is Associated with Multifocal Neuronal Hypoplasia by Zou, X, Bolon, B, Pretorius, J.K, Kurahara, C, McCabe, J, Christiansen, K.A, Sun, N, Duryea, D, Foreman, O, Senaldi, G, Itano, A.A, Siu, G

“…Mice with null mutations of ciliary neurotrophic factor (Cntf) receptor alpha (Cntf-Rα), or cytokine-like factor 1 (Clf), one component of Cntf-II (a…”
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Mice Overexpressing Murine Oncostatin M (OSM) Exhibit Changes in Hematopoietic and Other Organs that Are Distinct from Those of Mice Overexpressing Human OSM or Bovine OSM by Juan, T.S.-C, Bolon, B, Lindberg, R.A, Sun, Y, Van, G, Fletcher, F.A

“…Oncostatin M (OSM) and leukemia inhibitory factor (LIF) belong to the interleukin-6 family of cytokines. The authors' previous in vitro work demonstrated that…”
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Editorial: Best Pathology Practices in Research Using Genetically Engineered Mice by Bolon, B, Brayton, C, Cantor, G.H, Kusewitt, D.F, Loy, J.K, Sartin, E.A, Schoeb, T.R, Sellers, R.S, Schuh, J.C.L, Ward, J.M

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Interleukin-1β and Tumor Necrosis Factor-α Produce Distinct, Time-dependent Patterns of Acute Arthritis in the Rat Knee by Bolon, B., Campagnuolo, G., Zhu, L., Duryea, D., Zack, D., Feige, U.

“…Interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) synergistically induce and sustain arthritis. Two competing hypotheses of arthritis induction are 1)…”
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2008 ACVP Role Delineation Survey and Initial Data Analysis: From the Role Delineation Task Force by Morton, D, Berent, L.M, Bolon, B, Boyd, K.L, Coleman, G.D, Hall, R.L, Kinsel, M.J, Tornquist, S.J, Wilson, D.W

“…The American College of Veterinary Pathologists commissioned a role delineation survey to define the specialized tasks, knowledge, and tools that define the…”
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Osteoclast Numbers in Lewis Rats with Adjuvant-induced Arthritis: Identification of Preferred Sites and Parameters for Rapid Quantitative Analysis by Bolon, B., Morony, S., Cheng, Y., Hu, Y.-L., Feige, U.

“…This study defined the best site for quantifying osteoclasts in male Lewis rats with mycobacteria-induced adjuvant arthritis. Hind paw sections of normal and…”
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Evolution of Alachlor-Induced Nasal Neoplasms in the Long-Evans Rat by Genter, Mary Beth, Burman, Dawn M., Dingeldein, Michael W., Clough, Ian, Bolon, Brad

“…The chloracetanilide herbicide alachlor (2-chloro-2',6-diethyl-N-(methoxymethyl)-acetanilide) induces nasal neoplasms in rats following chronic dietary…”
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Retinoic acid acts during peri-implantational development to alter axial and brain formation by Pauken, C M, LaBorde, J B, Bolon, B

“…All-trans retinoid acid (RA) induces a stereotypic spectrum of stage-specific malformations in vertebrate conceptuses. The present work evaluated the anatomic…”
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