Search Results - "Bollen, Edward LEM"

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial by Shepherd, James, Blauw, Gerard J, Murphy, Michael B, Bollen, Edward LEM, Buckley, Brendan M, Cobbe, Stuart M, Ford, Ian, Gaw, Allan, Hyland, Michael, Jukema, J Wouter, Kamper, Adriaan M, Macfarlane, Peter W, Meinders, A Edo, Norrie, John, Packard, Chris J, Perry, Ivan J, Stott, David J, Sweeney, Brian J, Twomey, Gillian, Westendorp, Rudi GJ

“…Although statins reduce coronary and cerebrovascular morbidity and mortality in middle-aged individuals, their efficacy and safety in elderly people is not…”
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A Prospective Study of Pravastatin in the Elderly at Risk (PROSPER): Screening Experience and Baseline Characteristics by Ford, Ian, Blauw, Gerard Jan, Murphy, Michael B, Shepherd, James, Cobbe, Stuart M, Bollen, Edward LEM, Buckley, Brendan M, Jukema, J Wouter, Hyland, Michael, Gaw, Allan, Lagaay, A Margot, Perry, Ivan J, Macfarlane, Peter, Norrie, John, Meinders, A Edo, Sweeney, Brian J, Packard, Chris J, Westendorp, Rudi GJ, Twomey, Cillian, Stott, David J

“…BACKGROUND: PROSPER was designed to investigate the benefits of treatment with pravastatin in elderly patients for whom a typical doctor might consider the…”
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Association Between Apolipoprotein E4 and Cognitive Decline in Elderly Adults by Packard, Chris J., Westendorp, Rudi G.J., Stott, David J., Caslake, Muriel J., Murray, Heather M., Shepherd, James, Blauw, Gerard J., Murphy, Michael B., Bollen, Edward L.E.M., Buckley, Brendan M., Cobbe, Stuart M., Ford, Ian, Gaw, Allan, Hyland, Michael, Jukema, J. Wouter, Kamper, Adriaan M., Macfarlane, Peter W., Jolles, Jellemer, Perry, Ivan J., Sweeney, Brian J., Twomey, Cillian

“…OBJECTIVE: To determine the influence of apolipoprotein E on cognitive decline in a cohort of elderly men and women. DESIGN: Prospective study. SETTING:…”
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Decline in total cerebral blood flow is linked with increase in periventricular but not deep white matter hyperintensities by ten Dam, V Hester, van den Heuvel, Dominique M J, de Craen, Anton J M, Bollen, Edward L E M, Murray, Heather M, Westendorp, Rudi G J, Blauw, Gerard J, van Buchem, Mark A

“…To retrospectively investigate the association between changes in total cerebral blood flow and progression of total, periventricular, and deep white matter…”
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Shape abnormalities of the striatum in Alzheimer's disease by de Jong, Laura W, Ferrarini, Luca, van der Grond, Jeroen, Milles, Julien R, Reiber, Johan H C, Westendorp, Rudi G J, Bollen, Edward L E M, Middelkoop, Huub A M, van Buchem, Mark A

“…Postmortem studies show pathological changes in the striatum in Alzheimer's disease (AD). Here, we examine the surface of the striatum in AD and assess whether…”
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Detection of a Soluble Form of BACE-1 in Human Cerebrospinal Fluid by a Sensitive Activity Assay by Verheijen, Jan H, Huisman, Linda G.M, van Lent, Natascha, Neumann, Ulf, Paganetti, Paolo, Hack, C. Erik, Bouwman, Femke, Lindeman, Jan, Bollen, Edward L.E.M, Hanemaaijer, Roeland

“…Formation of deposits of the insoluble amyloid beta-peptide is believed to be causally related with neurodegeneration in Alzheimer disease (AD). The…”
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Association Between Apolipoprotein E sub(4) and Cognitive Decline in Elderly Adults by Packard, Chris J, Westendorp, Rudi GJ, Stott, David J, Caslake, Muriel J, Murray, Heather M, Shepherd, James, Blauw, Gerard J, Murphy, Michael B, Bollen, Edward LEM, Buckley, Brendan M, Cobbe, Stuart M, d, Ian, Gaw, Allan, Hyland, Michael, Jukema, JWouter, Kamper, Adriaan M, Macfarlane, Peter W, Jolles, Jellemer, Perry, Ivan J, Sweeney, Brian J, Twomey, Cillian

“…OBJECTIVETo determine the influence of apolipoprotein E on cognitive decline in a cohort of elderly men and women. DESIGNProspective study. SETTINGScotland,…”
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