Search Results - "Bollag, Wendy B."
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Exploring Skin Wound Healing Models and the Impact of Natural Lipids on the Healing Process
Published in International journal of molecular sciences (01-04-2024)“…Cutaneous wound healing is a complex biological process involving a series of well-coordinated events aimed at restoring skin integrity and function. Various…”
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Aquaporins in the Cornea
Published in International journal of molecular sciences (01-04-2024)“…The cornea is an avascular, transparent tissue that allows light to enter the visual system. Accurate vision requires proper maintenance of the cornea's…”
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De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing
Published in Journal of lipid research (01-07-2022)Get full text
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The role of lipid second messengers in aldosterone synthesis and secretion
Published in Journal of lipid research (01-04-2022)“…Second messengers are small rapidly diffusing molecules or ions that relay signals between receptors and effector proteins to produce a physiological effect…”
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Phosphatidylglycerol and surfactant: A potential treatment for COVID-19?
Published in Medical hypotheses (01-11-2020)“…A hypothesis concerning the potential utility of surfactant supplementation for the treatment of critically ill patients with COVID-19 is proposed, along with…”
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Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis
Published in Circulation (New York, N.Y.) (01-12-2015)“…BACKGROUND—In obesity, the excessive synthesis of aldosterone contributes to the development and progression of metabolic and cardiovascular dysfunctions…”
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Acute and chronic regulation of aldosterone production
Published in Molecular and cellular endocrinology (24-03-2012)“…► Aldosterone is the major mineralocorticoid produced by the adrenal zona glomerulosa. ► Glomerulosa cells are primarily regulated by angiotensin II, serum…”
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Innate Immune System Activation, Inflammation and Corneal Wound Healing
Published in International journal of molecular sciences (29-11-2022)“…Corneal wounds resulting from injury, surgeries, or other intrusions not only cause pain, but also can predispose an individual to infection. While some…”
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Pathogen-Associated Molecular Pattern-Induced TLR2 and TLR4 Activation Increases Keratinocyte Production of Inflammatory Mediators and is Inhibited by Phosphatidylglycerol
Published in Molecular pharmacology (01-05-2020)“…Skin serves not only as a protective barrier to microbial entry into the body but also as an immune organ. The outer layer, the epidermis, is composed…”
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The Skin and Inflamm-Aging
Published in Biology (Basel, Switzerland) (01-11-2023)“…With its unique anatomical location facing both the external and internal environment, the skin has crucial functions, including shielding the body from damage…”
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Phosphatidylglycerol Inhibits Toll-Like Receptor–Mediated Inflammation by Danger-Associated Molecular Patterns
Published in Journal of investigative dermatology (01-04-2019)“…Psoriasis is a common skin disorder characterized by hyperproliferation and aberrant differentiation of epidermal keratinocytes and inflammation. We previously…”
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The Role of PGC-1α in Aging Skin Barrier Function
Published in Cells (Basel, Switzerland) (02-07-2024)“…Skin provides a physical and immune barrier to protect the body from foreign substances, microbial invasion, and desiccation. Aging reduces the barrier…”
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The Role of Tryptophan Metabolites in Musculoskeletal Stem Cell Aging
Published in International journal of molecular sciences (11-09-2020)“…Although aging is considered a normal process, there are cellular and molecular changes that occur with aging that may be detrimental to health. Osteoporosis…”
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Advanced Glycation End Products and Activation of Toll-like Receptor-2 and -4 Induced Changes in Aquaporin-3 Expression in Mouse Keratinocytes
Published in International journal of molecular sciences (10-01-2023)“…Prolonged inflammation and impaired re-epithelization are major contributing factors to chronic non-healing diabetic wounds; diabetes is also characterized by…”
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Distinct effects of different phosphatidylglycerol species on mouse keratinocyte proliferation
Published in PloS one (18-09-2014)“…We have previously shown that liposomes composed of egg-derived phosphatidylglycerol (PG), with a mixed fatty acid composition (comprising mainly palmitate and…”
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Phosphatidylglycerol to Treat Chronic Skin Wounds in Diabetes
Published in Pharmaceutics (14-05-2023)“…This review proposes the use of dioleoylphosphatidylglycerol (DOPG) to enhance diabetic wound healing. Initially, the characteristics of diabetic wounds are…”
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Glycerol Improves Skin Lesion Development in the Imiquimod Mouse Model of Psoriasis: Experimental Confirmation of Anecdotal Reports from Patients with Psoriasis
Published in International journal of molecular sciences (15-08-2021)“…Glycerol is used in many skin care products because it improves skin function. Anecdotal reports by patients on the National Psoriasis Foundation website also…”
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Dioleoylphosphatidylglycerol Inhibits Heat Shock Protein B4 (HSPB4)-Induced Inflammatory Pathways In Vitro
Published in International journal of molecular sciences (01-03-2023)“…Our previous work shows that dioleoylphosphatidylglycerol (DOPG) accelerates corneal epithelial healing in vitro and in vivo by unknown mechanisms. Prior data…”
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Hyperhomocysteinemia-induced death of retinal ganglion cells: The role of Müller glial cells and NRF2
Published in Redox biology (01-06-2019)“…Hyperhomocysteinemia (Hhcy), or increased levels of the excitatory amino acid homocysteine (Hcy), is implicated in glaucoma, a disease characterized by…”
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The caveolin-1 scaffolding domain peptide decreases phosphatidylglycerol levels and inhibits calcium-induced differentiation in mouse keratinocytes
Published in PloS one (13-11-2013)“…Phospholipase D2 (PLD2) has been found localized in low-density caveolin-rich membrane microdomains. Our previous study suggested that PLD2 and aquaporin 3…”
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