Search Results - "Bolinger, Beatrice"

Aggravation of viral hepatitis by platelet-derived serotonin by Zinkernagel, Rolf M, Lang, Karl S, Lang, Philipp A, Contaldo, Claudio, Georgiev, Panco, El-Badry, Ashraf Mohammad, Recher, Mike, Kurrer, Michael, Cervantes-Barragan, Luisa, Ludewig, Burkhard, Calzascia, Thomas, Bolinger, Beatrice, Merkler, Doron, Odermatt, Bernhard, Bader, Michael, Graf, Rolf, Clavien, Pierre-Alain, Hegazy, Ahmed N, Löhning, Max, Harris, Nicola L, Ohashi, Pamela S, Hengartner, Hans

“…More than 500 million people worldwide are persistently infected with hepatitis B virus or hepatitis C virus. Although both viruses are poorly cytopathic,…”
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CD73 is dispensable for the regulation of inflationary CD8+ T-cells after murine cytomegalovirus infection and adenovirus immunisation by Sims, Stuart, Colston, Julia, Bolinger, Beatrice, Emery, Vince, Klenerman, Paul

“…The ecto-5'-nucleotidase (CD73) is expressed by T-cell subsets, myeloid derived suppressive cells and endothelial cells. It works in conjunction with CD39 to…”
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Adenoviral vaccine induction of CD8+ T cell memory inflation: Impact of co-infection and infection order by Lee, Lian N, Bolinger, Beatrice, Banki, Zoltan, de Lara, Catherine, Highton, Andrew J, Colston, Julia M, Hutchings, Claire, Klenerman, Paul

“…The efficacies of many new T cell vaccines rely on generating large populations of long-lived pathogen-specific effector memory CD8 T cells. However, it is now…”
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Adenoviral Vector Vaccination Induces a Conserved Program of CD8+ T Cell Memory Differentiation in Mouse and Man by Bolinger, Beatrice, Sims, Stuart, Swadling, Leo, O’Hara, Geraldine, de Lara, Catherine, Baban, Dilair, Saghal, Natasha, Lee, Lian Ni, Marchi, Emanuele, Davis, Mark, Newell, Evan, Capone, Stefania, Folgori, Antonella, Barnes, Ellie, Klenerman, Paul

“…Following exposure to vaccines, antigen-specific CD8+ T cell responses develop as long-term memory pools. Vaccine strategies based on adenoviral vectors, e.g.,…”
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Immunopathological Basis of Lymphocytic Choriomeningitis Virus-Induced Chorioretinitis and Keratitis by ZINKEMAGEL, Martin S, BOLINGER, Beatrice, KREBS, Philippe, ONDER, Lucas, MILLER, Simone, LUDEWIG, Burkhard

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Increasing inflationary T‐cell responses following transient depletion of MCMV‐specific memory T cells by Sims, Stuart, Klenerman, Paul

“…Murine CMV (MCMV) infection induces effector CD8+ T cells that continue to increase in frequency after acute infection (“inflation”) and are stably maintained…”
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Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone by Scandella, Elke, Miller, Simone, Finke, Daniela, Littman, Dan R, Bolinger, Beatrice, Favre, Stéphanie, Junt, Tobias, Ludewig, Burkhard, Luther, Sanjiv A, Lattmann, Evelyn

“…The generation of lymphoid microenvironments in early life depends on the interaction of lymphoid tissue–inducer cells with stromal lymphoid tissue–organizer…”
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Modification of Antigen Impacts on Memory Quality after Adenovirus Vaccination by Colston, Julia M, Bolinger, Beatrice, Cottingham, Matthew G, Gilbert, Sarah, Klenerman, Paul

“…The establishment of robust T cell memory is critical for the development of novel vaccines for infections and cancers. Classical memory generated by CD8(+)T…”
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Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity by Jayachandran, Rajesh, Gumienny, Aleksandra, Bolinger, Beatrice, Ruehl, Sebastian, Lang, Mathias Jakob, Fucile, Geoffrey, Mazumder, Saumyabrata, Tchang, Vincent, Woischnig, Anne-Kathrin, Stiess, Michael, Kunz, Gabriele, Claudi, Beatrice, Schmaler, Mathias, Siegmund, Kerstin, Li, Jianping, Dertschnig, Simone, Holländer, George, Medina, Eva, Karrer, Urs, Moshous, Despina, Bumann, Dirk, Khanna, Nina, Rossi, Simona W., Pieters, Jean

“…The ability of the immune system to discriminate self from non-self is essential for eradicating microbial pathogens but is also responsible for allograft…”
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Mutation of a Self-Processing Site in Caspase-8 Compromises Its Apoptotic but Not Its Nonapoptotic Functions in Bacterial Artificial Chromosome-Transgenic Mice by Kang, Tae-Bong, Oh, Gi-Su, Scandella, Elke, Bolinger, Beatrice, Ludewig, Burkhard, Kovalenko, Andrew, Wallach, David

“…Caspase-8, the proximal enzyme in the death-induction pathway of the TNF/nerve growth factor receptor family, is activated upon juxtaposition of its molecules…”
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A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector by Bolinger, Beatrice, Sims, Stuart, O'Hara, Geraldine, de Lara, Catherine, Tchilian, Elma, Firner, Sonja, Engeler, Daniel, Ludewig, Burkhard, Klenerman, Paul

“…CD8(+) T cell memory inflation, first described in murine CMV (MCMV) infection, is characterized by the accumulation of high-frequency, functional Ag-specific…”
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Adenoviral vaccine induction of CD8.sup.+ T cell memory inflation: Impact of co-infection and infection order by Lee, Lian N, Bolinger, Beatrice, Banki, Zoltan, de Lara, Catherine, Highton, Andrew J, Colston, Julia M, Hutchings, Claire, Klenerman, Paul

“…The efficacies of many new T cell vaccines rely on generating large populations of long-lived pathogen-specific effector memory CD8 T cells. However, it is now…”
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A novel murine cytomegalovirus vaccine vector protects against Mycobacterium tuberculosis by Beverley, Peter C L, Ruzsics, Zsolt, Hey, Ariann, Hutchings, Claire, Boos, Simone, Bolinger, Beatrice, Marchi, Emanuele, O'Hara, Geraldine, Klenerman, Paul, Koszinowski, Ulrich H, Tchilian, Elma Z

“…Tuberculosis remains a global health problem so that a more effective vaccine than bacillus Calmette-Guérin is urgently needed. Cytomegaloviruses persist…”
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A minimum number of autoimmune T cells to induce autoimmunity? by Bosch, Angela J.T., Bolinger, Beatrice, Keck, Simone, Stepanek, Ondrej, Ozga, Aleksandra J., Galati-Fournier, Virginie, Stein, Jens V., Palmer, Ed

“…•Determination of minimal T cell number for autoimmunity in a mouse model.•2–5 autoimmune T cells can induce lethal diabetes.•Outgrowth of dominant T cell…”
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Environmental effects on protection against Mycobacterium tuberculosis after immunization with Ad85A by Beverley, Peter, Ronan, Edward, Lee, Lianni, Arnold, Isabelle, Bolinger, Beatrice, Powrie, Fiona, Tchilian, Elma

“…Highlights ► The environment alters the immune response to an intradermal (i.d.) TB subunit vaccine, Ad85A. ► Ad85A i.d. induces a lung immune response but is…”
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An adenoviral model to unlock the secrets of memory inflation? by Colston, Julia, Bolinger, Beatrice, Turner, Alison, Gilbert, Sarah, Klenerman, Paul

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Environmental effects on protection againstMycobacterium tuberculosisafter immunization with Ad85A by Beverley, Peter, Ronan, Edward, Lee, Lianni, Arnold, Isabelle, Bolinger, Beatrice, Powrie, Fiona, Tchilian, Elma

“…Highlights * The environment alters the immune response to an intradermal (i.d.) TB subunit vaccine, Ad85A. * Ad85A i.d. induces a lung immune response but is…”
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A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector1 by Bolinger, Beatrice, Sims, Stuart, O’Hara, Geraldine, de Lara, Catherine, Tchilian, Elma, Firner, Sonja, Engeler, Daniel, Ludewig, Burkhard, Klenerman, Paul

“…CD8 + T cell memory inflation, first described in murine cytomegalovirus (MCMV) infection, is characterized by the accumulation of high-frequency, functional…”
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Systemic minor histocompatibility antigen expression in blood endothelial cells prevents T cell‐mediated vascular immunopathology by Caviezel‐Firner, Sonja, Engeler, Daniel, Bolinger, Beatrice, Onder, Lucas, Scandella, Elke, Yu, Meimei, Kroczek, Richard. A., Ludewig, Burkhard

“…Attenuation of T cell‐mediated damage of blood endothelial cells (BECs) in transplanted organs is important to prevent transplant vasculopathy (TV) and chronic…”
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Chronic Immune Reactivity Against Persisting Microbial Antigen in the Vasculature Exacerbates Atherosclerotic Lesion Formation by Krebs, Philippe, Scandella, Elke, Bolinger, Beatrice, Engeler, Daniel, Miller, Simone, Ludewig, Burkhard

“…OBJECTIVE—The purpose of this study was to examine the relative contribution of different immunopathological mechanisms during murine cytomegalovirus…”
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