Search Results - "Bolijn, Marije"

A Novel Platinum(II)-Based Bifunctional ADC Linker Benchmarked Using 89Zr-Desferal and Auristatin F-Conjugated Trastuzumab by Sijbrandi, Niels J, Merkul, Eugen, Muns, Joey A, Waalboer, Dennis C J, Adamzek, Kevin, Bolijn, Marije, Montserrat, Veronica, Somsen, Govert W, Haselberg, Rob, Steverink, Paul J G M, Houthoff, Hendrik-Jan, van Dongen, Guus A M S

“…Greater control is desirable in the stochastic conjugation technology used to synthesize antibody-drug conjugates (ADC). We have shown recently that a…”
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Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines by Klein, Christian, Waldhauer, Inja, Nicolini, Valeria G., Freimoser-Grundschober, Anne, Nayak, Tapan, Vugts, Danielle J., Dunn, Claire, Bolijn, Marije, Benz, Jörg, Stihle, Martine, Lang, Sabine, Roemmele, Michaele, Hofer, Thomas, van Puijenbroek, Erwin, Wittig, David, Moser, Samuel, Ast, Oliver, Brünker, Peter, Gorr, Ingo H., Neumann, Sebastian, de Vera Mudry, Maria Cristina, Hinton, Heather, Crameri, Flavio, Saro, Jose, Evers, Stefan, Gerdes, Christian, Bacac, Marina, van Dongen, Guus, Moessner, Ekkehard, Umaña, Pablo

“…We developed cergutuzumab amunaleukin (CEA-IL2v, RG7813), a novel monomeric CEA-targeted immunocytokine, that comprises a single IL-2 variant (IL2v) moiety…”
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Development of novel ADCs: conjugation of tubulysin analogues to trastuzumab monitored by dual radiolabeling by Cohen, Ruth, Vugts, Danielle J, Visser, Gerard W M, Stigter-van Walsum, Marijke, Bolijn, Marije, Spiga, Marco, Lazzari, Paolo, Shankar, Sreejith, Sani, Monica, Zanda, Matteo, van Dongen, Guus A M S

“…Tubulysins are highly toxic tubulin-targeting agents with a narrow therapeutic window that are interesting for application in antibody-drug conjugates (ADC)…”
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Development of [11C]vemurafenib employing a carbon-11 carbonylative Stille coupling and preliminary evaluation in mice bearing melanoma tumor xenografts by Slobbe, Paul, Windhorst, Albert D, Adamzek, Kevin, Bolijn, Marije, Schuit, Robert C, Heideman, Daniëlle A M, van Dongen, Guus A M S, Poot, Alex J

“…Over the last decade kinase inhibitors have witnessed tremendous growth as anti-cancer drugs. Unfortunately, despite their promising clinical successes, a…”
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