Search Results - "Bolger, Morgan W."

The Contribution of Perilacunar Composition and Mechanical Properties to Whole-Bone Mechanical Outcomes in Streptozotocin-Induced Diabetes by Bolger, Morgan W., Tekkey, Tara, Kohn, David H.

“…Osteocytes are the most abundant cell type in bone and remodel their local perilacunar matrix in response to a variety of stimuli and diseases. How the…”
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Beyond bone volume: Understanding tissue-level quality in healing of maxillary vs. femoral defects by Romanowicz, Genevieve E., Zhang, Lizhong, Bolger, Morgan W., Lynch, Michelle, Kohn, David H.

“…Currently, principles of tissue engineering and implantology are uniformly applied to all bone sites, disregarding inherent differences in collagen, mineral…”
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Peripheral canalicular branching is decreased in streptozotocin-induced diabetes and correlates with decreased whole-bone ultimate load and perilacunar elastic work by Bolger, Morgan W, Tekkey, Tara, Kohn, David H

“…Osteocytes, the most abundant cell type in bone, play a crucial role in mechanosensation and signaling for bone formation and resorption. These cells reside…”
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Divergent mechanical properties of older human male femora reveal unique combinations of morphological and compositional traits contributing to low strength by Bolger, Morgan W., Romanowicz, Genevieve E., Bigelow, Erin M.R., Ward, Ferrous S., Ciarelli, Antonio, Jepsen, Karl J., Kohn, David H.

“…Bone strength is generally thought to decline with aging and prior work has compared traits between younger and older cohorts to identify the structural and…”
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External bone size identifies different strength-decline trajectories for the male human femora by Bolger, Morgan W., Romanowicz, Genevieve E., Bigelow, Erin M.R., Ward, Ferrous S., Ciarelli, Antonio, Jepsen, Karl J., Kohn, David H.

“…[Display omitted] •Cortical midshaft morphology predicts age-related declines in mechanical properties.•Wide bones exhibit greater declines in mechanical…”
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Advancements in composition and structural characterization of bone to inform mechanical outcomes and modeling by Bolger, Morgan W., Romanowicz, Genevieve E., Kohn, David H.

“…Advancements in imaging, computing, microscopy, chromatography, spectroscopy, and biological manipulations of animal models have allowed for a more thorough…”
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