Search Results - "Bolduc, C"

A prospective phase III, randomized, double-blind, placebo-controlled study of brodalumab in patients with moderate-to-severe plaque psoriasis by Papp, K.A., Reich, K., Paul, C., Blauvelt, A., Baran, W., Bolduc, C., Toth, D., Langley, R.G., Cather, J., Gottlieb, A.B., Thaçi, D., Krueger, J.G., Russell, C.B., Milmont, C.E., Li, J., Klekotka, P.A., Kricorian, G., Nirula, A.

“…Summary Background The interleukin‐17 cytokine family plays a central role in psoriasis pathogenesis. Objectives To evaluate the efficacy and safety of…”
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A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis by Ports, W.C., Khan, S., Lan, S., Lamba, M., Bolduc, C., Bissonnette, R., Papp, K.

“…Summary Background Tofacitinib (CP‐690,550) is a novel Janus kinase inhibitor in development as an oral formulation for the treatment of several inflammatory…”
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Staphylococcus aureus Tet38 Efflux Pump Structural Modeling and Roles of Essential Residues in Drug Efflux and Host Cell Internalization by Truong-Bolduc, Q C, Wang, Y, Hooper, D C

“…The Tet38 membrane protein has distinct functions, including drug efflux and host cell attachment and internalization mediated by interaction with host cell…”
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Tet38 Efflux Pump Contributes to Fosfomycin Resistance in Staphylococcus aureus by Truong-Bolduc, Q C, Wang, Y, Hooper, D C

“…Fosfomycin inhibits MurA following uptake by the GlpT transporter of glycerol-3-phosphate in In , plasmid overexpression of the Tet38 efflux pump and a mutant…”
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Tet38 of Staphylococcus aureus Binds to Host Cell Receptor Complex CD36-Toll-Like Receptor 2 and Protects from Teichoic Acid Synthesis Inhibitors Tunicamycin and Congo Red by Truong-Bolduc, Q C, Wang, Y, Hooper, D C

“…Using an affinity column retention assay, we showed that the purified Tet38 membrane transporter of bound specifically to host cell CD36 and to the complex…”
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Staphylococcus aureus Efflux Pumps and Tolerance to Ciprofloxacin and Chlorhexidine following Induction by Mupirocin by Truong-Bolduc, Q C, Wang, Y, Reedy, J L, Vyas, J M, Hooper, D C

“…Mupirocin induced expression of genes encoding efflux pumps NorA and MepA as well as a yellow fluorescent protein (YFP) fluorescence reporter of NorA…”
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MgrA Is a Multiple Regulator of Two New Efflux Pumps in Staphylococcus aureus by TRUONG-BOLDUC, Q. C, DUNMAN, P. M, STRAHILEVITZ, J, PROJAN, S. J, HOOPER, D. C

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Role of the Tet38 Efflux Pump in Staphylococcus aureus Internalization and Survival in Epithelial Cells by Truong-Bolduc, Q C, Bolduc, G R, Medeiros, H, Vyas, J M, Wang, Y, Hooper, D C

“…We previously identified the protein Tet38 as a chromosomally encoded efflux pump of Staphylococcus aureus that confers resistance to tetracycline and certain…”
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Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump by Truong-Bolduc, Q C, Wang, Y, Chen, C, Hooper, D C

“…TetR21 controls the expression of Tet38 and LmrS efflux pumps. A mutant, QT21, exhibited a 4-fold increase in the transcription level of overexpressor showed…”
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Efficacy and safety of topical WBI-1001 in patients with mild to moderate psoriasis: results from a randomized double-blind placebo-controlled, phase II trial by Bissonnette, R., Bolduc, C., Maari, C., Nigen, S., Webster, J.M., Tang, L., Lyle, M.

“…Background  There is a need for the development of novel non‐steroidal topical drugs for the treatment of psoriasis. Objective  To assess the efficacy and…”
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Treatment of palmoplantar psoriasis with infliximab: a randomized, double-blind placebo-controlled study by Bissonnette, R., Poulin, Y., Guenther, L., Lynde, C.W., Bolduc, C., Nigen, S.

“…Background  Palmoplantar psoriasis is a difficult to treat variant of plaque psoriasis. Objective  To study the safety and efficacy of infliximab in…”
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Antimicrobial activity of extracts from macroalgae Ulva lactuca against clinically important Staphylococci is impacted by lunar phase of macroalgae harvest by Deveau, A.M., Miller‐Hope, Z., Lloyd, E., Williams, B.S., Bolduc, C., Meader, J.M., Weiss, F., Burkholder, K.M.

“…Staphylococcus aureus is a common human bacterial pathogen that causes skin and soft tissue infections. Methicillin‐resistant Staph. aureus (MRSA) are…”
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A perturbation metaheuristic for the vehicle routing problem with private fleet and common carriers by Bolduc, M-C, Renaud, J, Boctor, F, Laporte, G

“…The purpose of this article is to propose a perturbation metaheuristic for the vehicle routing problem with private fleet and common carrier (VRPPC). This…”
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Probability of Exceedance Estimates for Scour Depth around Bridge Piers by Bolduc, Laura C, Gardoni, Paolo, Briaud, Jean-Louis

“…Scour at a bridge pier is the formation of a hole around the pier due to the erosion of soil by flowing water; this hole in the soil reduces the carrying…”
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A Reconstruction of Ultraviolet Spectral Irradiance During the Maunder Minimum by Bolduc, C., Charbonneau, P., Barnabé, R., Bourqui, M. S.

“…We present a reconstruction of the solar spectrum in the near and mid-ultraviolet spectral range during the Maunder Minimum, a period of strongly suppressed…”
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Transcriptional Profiling Analysis of the Global Regulator NorG, a GntR-Like Protein of Staphylococcus aureus by TRUONG-BOLDUC, Q. C, DUNMAN, P. M, EIDEM, T, HOOPER, D. C

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Summary of North American Hair Research Society (NAHRS)-sponsored Workshop on Cicatricial Alopecia, Duke University Medical Center, February 10 and 11, 2001 by Olsen, Elise A., Bergfeld, Wilma F., Cotsarelis, George, Price, Vera H., Shapiro, Jerry, Sinclair, Rodney, Solomon, Alvin, Sperling, Leonard, Stenn, Kurt, Whiting, David A.

“…J Am Acad Dermatol 2003;48:103-10…”
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A new scalp formulation of calcipotriol plus betamethasone dipropionate compared with each of its active ingredients in the same vehicle for the treatment of scalp psoriasis: a randomized, double-blind, controlled trial by Van De Kerkhof, P.C.M., Hoffmann, V., Anstey, A., Barnes, L., Bolduc, C., Reich, K., Saari, S., Segaert, S., Vaillant, L.

“…Summary Background  There is a need for new treatments for scalp psoriasis, as many topical treatments are cosmetically unacceptable and difficult to apply,…”
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Test-retest reliability of lower limb isokinetic endurance in COPD: A comparison of angular velocities by Ribeiro, Fernanda, Lépine, Pierre-Alexis, Garceau-Bolduc, Corine, Coats, Valérie, Allard, Étienne, Maltais, François, Saey, Didier

“…The purpose of this study was to determine and compare the test-retest reliability of quadriceps isokinetic endurance testing at two knee angular velocities in…”
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DESCRIPTION OF FREQUENT USERS IN THE EMERGENCY DEPARTMENT TO IMPROVE CARE by Bolduc, C, Cossette, S, Beaulieu, V, Carbonneau, M.-H

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