Search Results - "Boldogh, István"

Oxidized base 8-oxoguanine, a product of DNA repair processes, contributes to dendritic cell activation by Pázmándi, Kitti, Sütő, Máté, Fekete, Tünde, Varga, Aliz, Boldizsár, Eszter, Boldogh, István, Bácsi, Attila

“…A growing body of evidence suggests that elevated levels of reactive oxygen species (ROS) in the airways caused by exposure to gas phase pollutants or…”
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Exercise improves import of 8-oxoguanine DNA glycosylase into the mitochondrial matrix of skeletal muscle and enhances the relative activity by Radak, Zsolt, Atalay, Mustafa, Jakus, Judit, Boldogh, István, Davies, Kelvin, Goto, Sataro

“…Exercise has been shown to modify the level/activity of the DNA damage repair enzyme 8-oxoguanine-DNA glycosylase (OGG1) in skeletal muscle. We have studied…”
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Exposure to inhomogeneous static magnetic field beneficially affects allergic inflammation in a murine model by Csillag, Anikó, Kumar, Brahma V., Szabó, Krisztina, Szilasi, Mária, Papp, Zsuzsa, Szilasi, Magdolna E., Pázmándi, Kitti, Boldogh, István, Rajnavölgyi, Éva, Bácsi, Attila, László, János F.

“…Previous observations suggest that static magnetic field (SMF)-exposure acts on living organisms partly through reactive oxygen species (ROS) reactions. In…”
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Actin Dynamics Affect Mitochondrial Quality Control and Aging in Budding Yeast by Higuchi, Ryo, Vevea, Jason D., Swayne, Theresa C., Chojnowski, Robert, Hill, Vanessa, Boldogh, Istvan R., Pon, Liza A.

“…Actin cables of budding yeast are bundles of F-actin that extend from the bud tip or neck to the mother cell tip, serve as tracks for bidirectional cargo…”
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Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation by Visnes, Torkild, Cázares-Körner, Armando, Hao, Wenjing, Wallner, Olov, Masuyer, Geoffrey, Loseva, Olga, Mortusewicz, Oliver, Wiita, Elisée, Sarno, Antonio, Manoilov, Aleksandr, Astorga-Wells, Juan, Jemth, Ann-Sofie, Pan, Lang, Sanjiv, Kumar, Karsten, Stella, Gokturk, Camilla, Grube, Maurice, Homan, Evert J, Hanna, Bishoy M F, Paulin, Cynthia B J, Pham, Therese, Rasti, Azita, Berglund, Ulrika Warpman, von Nicolai, Catharina, Benitez-Buelga, Carlos, Koolmeister, Tobias, Ivanic, Dag, Iliev, Petar, Scobie, Martin, Krokan, Hans E, Baranczewski, Pawel, Artursson, Per, Altun, Mikael, Jensen, Annika Jenmalm, Kalderén, Christina, Ba, Xueqing, Zubarev, Roman A, Stenmark, Pål, Boldogh, Istvan, Helleday, Thomas

“…The onset of inflammation is associated with reactive oxygen species and oxidative damage to macromolecules like 7,8-dihydro-8-oxoguanine (8-oxoG) in DNA…”
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The roles of base excision repair enzyme OGG1 in gene expression by Wang, Ruoxi, Hao, Wenjing, Pan, Lang, Boldogh, Istvan, Ba, Xueqing

“…Modifications of DNA strands and nucleobases—both induced and accidental—are associated with unfavorable consequences including loss or gain in genetic…”
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A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease by Area-Gomez, Estela, de Groof, Ad, Bonilla, Eduardo, Montesinos, Jorge, Tanji, Kurenai, Boldogh, Istvan, Pon, Liza, Schon, Eric A.

“…In the last few years, increased emphasis has been devoted to understanding the contribution of mitochondria-associated endoplasmic reticulum (ER) membranes…”
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Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome by Abraham, Dora, Feher, Janos, Scuderi, Gian Luca, Szabo, Dora, Dobolyi, Arpad, Cservenak, Melinda, Juhasz, Janos, Ligeti, Balazs, Pongor, Sandor, Gomez-Cabrera, Mari Carmen, Vina, Jose, Higuchi, Mitsuru, Suzuki, Katsuhiro, Boldogh, Istvan, Radak, Zsolt

“…It has been suggested that exercise training and probiotic supplementation could decelerate the progress of functional and biochemical deterioration in APP/PS1…”
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Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects by Mitra, Joy, Guerrero, Erika N., Hegde, Pavana M., Liachko, Nicole F., Wang, Haibo, Vasquez, Velmarini, Gao, Junling, Pandey, Arvind, Taylor, J. Paul, Kraemer, Brian C., Wu, Ping, Boldogh, Istvan, Garruto, Ralph M., Mitra, Sankar, Rao, K. S., Hegde, Muralidhar L.

“…Genome damage and their defective repair have been etiologically linked to degenerating neurons in many subtypes of amyotrophic lateral sclerosis (ALS)…”
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Role for cER and Mmr1p in Anchorage of Mitochondria at Sites of Polarized Surface Growth in Budding Yeast by Swayne, Theresa C., Zhou, Chun, Boldogh, Istvan R., Charalel, Joseph K., McFaline-Figueroa, José Ricardo, Thoms, Sven, Yang, Christine, Leung, Galen, McInnes, Joseph, Erdmann, Ralf, Pon, Liza A.

“…Mitochondria accumulate at neuronal and immunological synapses [1, 2] and yeast bud tips [3] and associate with the ER during phospholipid biosynthesis,…”
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Mitochondria on the move by Boldogh, Istvan R, Pon, Liza A

“…Interactions of mitochondria with the cytoskeleton are crucial for normal mitochondrial function and for localization of the organelle at its sites of action…”
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Isolation of mitochondria from Saccharomyces cerevisiae using magnetic bead affinity purification by Liao, Pin-Chao, Boldogh, Istvan R, Siegmund, Stephanie E, Freyberg, Zachary, Pon, Liza A

“…Isolated mitochondria are widely used to study the function of the organelle. Typically, mitochondria are prepared using differential centrifugation alone or…”
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The COVID-19 pandemic and physical activity by Woods, Jeffrey A., Hutchinson, Noah T., Powers, Scott K., Roberts, William O., Gomez-Cabrera, Mari Carmen, Radak, Zsolt, Berkes, Istvan, Boros, Anita, Boldogh, Istvan, Leeuwenburgh, Christiaan, Coelho-Júnior, Hélio José, Marzetti, Emanuele, Cheng, Ying, Liu, Jiankang, Durstine, J. Larry, Sun, Junzhi, Ji, Li Li

“…The SARS-CoV-2-caused COVID-19 pandemic has resulted in a devastating threat to human society in terms of health, economy, and lifestyle. Although the virus…”
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The systemic role of SIRT1 in exercise mediated adaptation by Radak, Zsolt, Suzuki, Katsuhiko, Posa, Aniko, Petrovszky, Zita, Koltai, Erika, Boldogh, Istvan

“…Cellular energy demands are readily changed during physical exercise resulting in adaptive responses by signaling proteins of metabolic processes, including…”
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Exercise effects on physiological function during aging by Radak, Zsolt, Torma, Ferenc, Berkes, Istvan, Goto, Sataro, Mimura, Tatsuya, Posa, Aniko, Balogh, Laszlo, Boldogh, Istvan, Suzuki, Katsuhiko, Higuchi, Mitsuru, Koltai, Erika

“…The decrease in cognitive/motor functions and physical abilities severely affects the aging population in carrying out daily activities. These disabilities…”
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Mitochondrial Dysfunction Increases Allergic Airway Inflammation by Aguilera-Aguirre, Leopoldo, Bacsi, Attila, Saavedra-Molina, Alfredo, Kurosky, Alexander, Sur, Sanjiv, Boldogh, Istvan

“…The prevalence of allergies and asthma among the world's population has been steadily increasing due to environmental factors. It has been described that…”
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Analysis of a Panel of 48 Cytokines in BAL Fluids Specifically Identifies IL-8 Levels as the Only Cytokine that Distinguishes Controlled Asthma from Uncontrolled Asthma, and Correlates Inversely with FEV1 by Hosoki, Koa, Ying, Sun, Corrigan, Christopher, Qi, Huibin, Kurosky, Alexander, Jennings, Kristofer, Sun, Qian, Boldogh, Istvan, Sur, Sanjiv

“…We sought to identify cells and cytokines in bronchoalveolar lavage (BAL) fluids that distinguish asthma from healthy control subjects and those that…”
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Exercise, oxidants, and antioxidants change the shape of the bell-shaped hormesis curve by Radak, Zsolt, Ishihara, Kazunari, Tekus, Eva, Varga, Csaba, Posa, Aniko, Balogh, Laszlo, Boldogh, Istvan, Koltai, Erika

“…It is debated whether exercise-induced ROS production is obligatory to cause adaptive response. It is also claimed that antioxidant treatment could eliminate…”
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8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors by Ba, Xueqing, Bacsi, Attila, Luo, Jixian, Aguilera-Aguirre, Leopoldo, Zeng, Xianlu, Radak, Zsolt, Brasier, Allan R, Boldogh, Istvan

“…Among the insidious DNA base lesions, 8-oxo-7,8-dihydroguanine (8-oxoG) is one of the most abundant, a lesion that arises through the attack by reactive oxygen…”
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Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization by Ke, Yueshuang, Lv, Xueping, Fu, Xingyue, Zhang, Jing, Bohio, Ameer Ali, Zeng, Xianlu, Hao, Wenjing, Wang, Ruoxi, Boldogh, Istvan, Ba, Xueqing

“…Poly(ADP-ribosyl)ation (PARylation) is an important post-translational modification mainly catalyzed by poly-ADP-ribose polymerase 1 (PARP1). In addition to…”
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