Search Results - "Bolaji, Oluseye O"

A snapshot of the prevalence of dihydropteroate synthase-431V mutation and other sulfadoxine-pyrimethamine resistance markers in Plasmodium falciparum isolates in Nigeria by Adegbola, Adebanjo J, Ijarotimi, Omotade A, Ubom, Akaninyene E, Adesoji, Bukola A, Babalola, Olajide E, Hocke, Emma F, Hansson, Helle, Mousa, Andria, Bolaji, Oluseye O, Alifrangis, Michael, Roper, Cally

“…Malaria is a major public health issue with substantial risks among vulnerable populations. Currently, the World Health Organization (WHO) recommends SP-IPTp…”
Get full text

Late presentation of chronic myeloid leukaemia patients in a low-income country: the prognostic implications and impact on treatment outcome by Nelson, Elisha A, Ahmed, Ibrahim O, Bolarinwa, Rahman A, Adeagbo, Babatunde A, Adegbola, Adebanjo J, Salawu, Lateef, Bolaji, Oluseye O, Durosinmi, Muheez A

“…In Nigeria, since 2002, Imatinib mesylate (glivec ) has been available freely to chronic myeloid leukaemia (CML) patients but only at a tertiary health care…”
Get full text

Thiopurine S-methyltransferase activity in Nigerians: phenotypes and activity reference values by Adehin, Ayorinde, Bolaji, Oluseye O

“…This study assessed the activity of thiopurine S-methyltransferase (TPMT) in Nigerians with a view to providing data on susceptibility to thiopurine toxicity,…”
Get full text

Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS by Olagunju, Adeniyi, Bolaji, Oluseye O, Amara, Alieu, Waitt, Catriona, Else, Laura, Soyinka, Julius, Adeagbo, Babatunde, Adejuyigbe, Ebunoluwa, Siccardi, Marco, Back, David, Owen, Andrew, Khoo, Saye

“…This manuscript describes the development, validation and clinical application of a novel method for the quantification of the antiretroviral drug efavirenz in…”
Get full text

A simple high-performance liquid chromatographic assay for concurrent quantification of lumefantrine and efavirenz in human plasma from malaria–HIV co-infected individuals by Adegbola, Adebanjo J., Ogboye, Ruth M., Soyinka, Julius O., Bolaji, Oluseye O.

“…Background As per current treatment guidelines, artemether-lumefantrine and efavirenz-based antiretroviral therapy are recommended drugs for falciparum malaria…”
Get full text

Pharmacokinetic Parameters of Quinine in Healthy Subjects and in Patients with Uncomplicated Malaria in Nigeria: Analysis of Data using a Population Approach by Adehin, Ayorinde, Igbinoba, Sharon I., Soyinka, Julius O., Onyeji, Cyprian O., Babalola, Chinedum P., Bolaji, Oluseye O.

“…•Varied disposition imparts on the tolerance and safety of quinine, and thus constitutes a major limiting consideration for its dosing in uncomplicated…”
Get full text

A randomized, open-label trial of combined nitazoxanide and atazanavir/ritonavir for mild to moderate COVID-19 by Fowotade, Adeola, Bamidele, Folasade, Egbetola, Boluwatife, Fagbamigbe, Adeniyi F, Adeagbo, Babatunde A, Adefuye, Bolanle O, Olagunoye, Ajibola, Ojo, Temitope O, Adebiyi, Akindele O, Olagunju, Omobolanle I, Ladipo, Olabode T, Akinloye, Abdulafeez, Onayade, Adedeji, Bolaji, Oluseye O, Rannard, Steve, Happi, Christian, Owen, Andrew, Olagunju, Adeniyi

“…The nitazoxanide plus atazanavir/ritonavir for COVID-19 (NACOVID) trial investigated the efficacy and safety of repurposed nitazoxanide combined with…”
Get full text

Prevalence of Vitamin A deficiency among under-five children in South-Western Nigeria by Abolurin, Olufunmilola, Adegbola, Adebanjo, Oyelami, Oyeku, Adegoke, Samuel, Bolaji, Oluseye

“…Background and Aim: Vitamin A deficiency (VAD) constitutes a major nutritional concern in developing countries. It contributes significantly to the morbidity…”
Get full text

Assessment of uptake of sulphadoxine-pyrimethamine for intermittent preventive treatment among pregnant women in Osun State, Nigeria by Adegbola, Adebanjo J, Ogboye, Ruth M, Ijarotimi, Omotade A, Ubom, Akaninyene E, Adesoji, Bukola A, Bolaji, Oluseye O

“…About 32 million pregnant women are at the risk of malaria infection yearly in malaria-endemic sub-Saharan Africa. To mitigate the risks associated with…”
Get full text

Pharmacogenomics in the Nigerian population: the past, the present and the future by Bolaji, Oluseye O, Adehin, Ayorinde, Adeagbo, Babatunde A

“…The Nigerian population exhibits huge ethnic and genetic diversity, typical of African populations, which can be harnessed for improved drug-response and…”
Get full text

Effect of CYP3A53 genotypes on lumefantrine plasma concentrations among malaria-HIV-infected women by Adegbola, Adebanjo J, Soyinka, Julius O, Bolaji, Oluseye O

“…Aim: We aimed to assess the effect of a functional polymorphism of CYP3A5 on lumefantrine pharmacokinetics. Patients & methods: Sixty-nine women diagnosed with…”
Get full text

Effect of CYP3A5 3 genotypes on lumefantrine plasma concentrations among malaria-HIV-infected women by Adegbola, Adebanjo J, Soyinka, Julius O, Bolaji, Oluseye O

“…We aimed to assess the effect of a functional polymorphism of CYP3A5 on lumefantrine pharmacokinetics. Sixty-nine women diagnosed with malaria received…”
Get full text

Influence of Amlodipine on the Disposition of Quinine in Healthy Volunteers by Eniayewu, Oluwasegun I., Adegbola, Adebanjo J., Adeagbo, Babatunde A., Bolaji, Oluseye O.

Get full text

Post-Marketing Surveillance of Quality of Artemether Injection Marketed in Southwest Nigeria by Hassan, Ibrahim A, Adegbola, Adebanjo J, Soyinka, Julius O, Onyeji, Cyprian O, Bolaji, Oluseye O

“…Access to good-quality medicines remains a contentious issue in developing countries. This development is worrisome, particularly in a setting with a high…”
Get full text

Inter-individual variation in imatinib disposition: any role for prevalent variants of CYP1A2, CYP2C8, CYP2C9, and CYP3A5 in Nigerian CML patients? by Adehin, Ayorinde, Adeagbo, Babatunde A., Kennedy, Martin A., Bolaji, Oluseye O., Olugbade, Tiwalade A., Bolarinwa, Rahman A., Durosinmi, Muheez A.

“…Imatinib has been successful in the management of chronic myeloid leukemia (CML) but some patients experience adverse reactions or develop resistance to its…”
Get full text

Influence of MAMA decoction, an Herbal Antimalarial, on the Pharmacokinetics of Amodiaquine in Mice by Adepiti, Awodayo O., Adeagbo, Babatunde A., Adehin, Ayorinde, Bolaji, Oluseye O., Elujoba, Anthony A.

“…Background and Objective MAMA decoction (MD) is an antimalarial product prepared from the leaves of Mangifera indica L. (Anacardiaceae), Alstonia boonei De…”
Get full text

Evaluation of herbal antimalarial MAMA decoction-amodiaquine combination in murine malaria model by Adepiti, Awodayo O., Elujoba, Anthony A., Bolaji, Oluseye O.

“…Context: Co-administration of amodiaquine with MAMA decoction (MD), an herbal antimalarial drug comprising the leaves of Mangifera indica L. (Anacardiaceae),…”
Get full text

Validation and pharmacokinetic application of a high-performance liquid chromatographic technique for determining the concentrations of amodiaquine and its metabolite in plasma of patients treated with oral fixed-dose amodiaquine-artesunate combination in areas of malaria endemicity by Adedeji, Olumuyiwa N, Bolaji, Oluseye O, Falade, Catherine O, Osonuga, Odusoga A, Ademowo, Olusegun G

“…Artemisinin-based combination therapies (ACTs) have been adopted by most African countries, including Nigeria, as first-line treatments for uncomplicated…”
Get full text

In vivo antimalarial evaluation of MAMA decoction on Plasmodium berghei in mice by Adepiti, Awodayo O, Elujoba, Anthony A, Bolaji, Oluseye O

“…The use of decoctions of different plant materials is common practice in antimalarial ethnomedicine in Africa. Scientific evaluation of such herbal…”
Get full text

Vitamin A deficiency among under-five Nigerian children with diarrhoea by Abolurin, Olufunmilola O, Adegbola, Adebanjo J, Oyelami, Oyeku A, Adegoke, Samuel A, Bolaji, Oluseye O

“…Background: Vitamin A deficiency (VAD) and diarrhoea are still important contributors to childhood deaths in Africa, and vitamin A deficient children are at…”
Get full text