Search Results - "Bol, K."
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Reflections on the Zhong Guo and the Yi Di with Reference to the Middle Period
Published in China review (Hong Kong, China : 1991) (01-05-2023)“…"Identity" for a group means both how we are the same and what makes us different from others. During the middle period, from the mid-Tang to the mid-Ming, the…”
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Case Report: Imaging immune checkpoint inhibitor-induced yin-yang effects in the brain
Published in Frontiers in immunology (02-06-2023)“…Treatment with immune checkpoint inhibitors (ICI) can induce durable responses in cancer patients, but it is commonly associated with serious immune-related…”
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Phase I/II study of single agent MCLA-128, a full length IgG1 bispecific antibody targeting the HER3 pathway: Overall safety at the recommended phase II dose (R2PD) and preliminary activity in HER2+ metastatic gastric/gastroesophageal junction cancer (GC/GEJ)
Published in Annals of oncology (01-10-2018)Get full text
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Modeling cancelation of periodic inputs with burst-STDP and feedback
Published in Neural networks (01-11-2013)“…Prediction and cancelation of redundant information is an important feature that many neural systems must display in order to efficiently code external…”
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Deregulated Expression of Insulin-Like Growth Factor 1 in Prostate Epithelium Leads to Neoplasia in Transgenic Mice
Published in Proceedings of the National Academy of Sciences - PNAS (28-03-2000)“…Transgenic mice expressing human insulin-like growth factor 1 (IGF-1) in basal epithelial cells of prostate have been characterized. Transgene expression led…”
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Health-related quality of life analysis in stage III melanoma patients treated with adjuvant dendritic cell therapy
Published in Clinical & translational oncology (01-06-2019)“…Background Health-related quality of life (HRQoL) is an important issue in the rapidly evolving field of adjuvant treatment for stage III melanoma. Dendritic…”
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Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion
Published in Cancer research (Chicago, Ill.) (15-03-2000)“…Transgenic mice overexpressing insulin-like growth factor-1 (IGF-1) in the basal layer of skin epidermis were generated using the bovine keratin 5 promoter…”
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Optimization of combined temozolomide and peptide receptor radionuclide therapy (PRRT) in mice after multimodality molecular imaging studies
Published in EJNMMI research (01-12-2015)“…Background Successful treatments of patients with somatostatin receptor (SSTR)-overexpressing neuroendocrine tumours (NET) comprise somatostatin-analogue…”
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Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor
Published in Cancer research (Chicago, Ill.) (01-05-2005)“…The insulin-like growth factor I receptor (IGF-IR) is a transmembrane tyrosine kinase that is essential to growth and development and also thought to provide a…”
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Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice
Published in Oncogene (10-04-1997)“…Transgenic animals were developed to assess the role of insulin-like growth factor 1 (IGF-1) in skin growth, differentiation and organization, as well as its…”
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Mapping China's History
Published in Verge (Minneapolis, Minn.) (22-09-2016)Get full text
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Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis
Published in Cancer research (Chicago, Ill.) (15-08-2003)“…In this study, we generated transgenic mice that overexpressed either a constitutively active human c-src mutant (src(530)) or a wild-type human c-src…”
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Imaging heterogeneity of peptide delivery and binding in solid tumors using SPECT imaging and MRI
Published in EJNMMI research (01-12-2016)“…Background As model system, a solid-tumor patient-derived xenograft (PDX) model characterized by high peptide receptor expression and histological tissue…”
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Induction of ornithine decarboxylase activity is a necessary step for mitogen-activated protein kinase kinase-induced skin tumorigenesis
Published in Cancer research (Chicago, Ill.) (15-01-2005)“…A transgenic mouse line overexpressing a constitutively active mutant of MEK1, a downstream effector of Ras, driven by the keratin 14 (K14) promoter, has been…”
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A Phase I Dose-Ranging Study of the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of AVN944, an IMPDH Inhibitor, in Healthy Male Volunteers
Published in Journal of clinical pharmacology (01-01-2009)“…A phase I study of AVN944, an inosine monophosphate dehydrogenase (IMPDH) inhibitor, was carried out to assess its safety, tolerability, pharmacokinetics, and…”
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On the unsupervised analysis of domain-specific Chinese texts
Published in Proceedings of the National Academy of Sciences - PNAS (31-05-2016)“…With the growing availability of digitized text data both publicly and privately, there is a great need for effective computational tools to automatically…”
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Normalization of kinship relations to enrich family network analysis: case study on China biographical database
Published in Digital Scholarship in the Humanities (02-04-2024)“…Abstract Kinship is an important issue in history studies. The kinship database is the key resource to analyze the structure, succession, and evolution of…”
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