Search Results - "Bokvist, Krister B."

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept by Coskun, Tamer, Sloop, Kyle W., Loghin, Corina, Alsina-Fernandez, Jorge, Urva, Shweta, Bokvist, Krister B., Cui, Xuewei, Briere, Daniel A., Cabrera, Over, Roell, William C., Kuchibhotla, Uma, Moyers, Julie S., Benson, Charles T., Gimeno, Ruth E., D'Alessio, David A., Haupt, Axel

“…A novel dual GIP and GLP-1 receptor agonist, LY3298176, was developed to determine whether the metabolic action of GIP adds to the established clinical…”
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682-P: Novel Dual Glucagon and Glucagon-Like Peptide-1 Receptor Agonist LY3305677 Improves Glucose Control, Reduces Body Weight, and Increases Energy Expenditure in Mice by CHEN, YANYUN, MEZO, ADAM, COSKUN, TAMER, SONG, MIN, ROELL, WILLIAM C., BOKVIST, KRISTER B., MOYERS, JULIE S., THOMAS, MELISSA K., VALENZUELA, FRANCISCO, QU, HONGCHANG

“…LY3305677 (LY) is a synthetic peptide analog of mammalian oxyntomodulin with a fatty acyl side chain to extend time action. LY functions are mediated by…”
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Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice by Templin, Andrew T., Meier, Daniel T., Willard, Joshua R., Wolden-Hanson, Tami, Conway, Kelly, Lin, Yin-Guo, Gillespie, Patrick J., Bokvist, Krister B., Attardo, Giorgio, Kahn, Steven E., Scheuner, Donalyn, Hull, Rebecca L.

“…Aims/hypothesis Islet amyloid deposits contribute to beta cell dysfunction and death in most individuals with type 2 diabetes but non-invasive methods to…”
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Regulation of Endogenous (Male) Rodent GLP-1 Secretion and Human Islet Insulin Secretion by Antagonism of Somatostatin Receptor 5 by Farb, Thomas B, Adeva, Marta, Beauchamp, Thomas J, Cabrera, Over, Coates, David A, Meredith, Tamika DeShea, Droz, Brian A, Efanov, Alexander, Ficorilli, James V, Gackenheimer, Susan L, Martinez-Grau, Maria A, Molero, Victoriano, Ruano, Gema, Statnick, Michael A, Suter, Todd M, Syed, Samreen K, Toledo, Miguel A, Willard, Francis S, Zhou, Xin, Bokvist, Krister B, Barrett, David G

“…Incretin and insulin responses to nutrient loads are suppressed in persons with diabetes, resulting in decreased glycemic control. Agents including…”
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Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in human islet amyloid polypeptide transgenic mice by Templin, Andrew T., Meier, Daniel T., Willard, Joshua R., Wolden-Hanson, Tami, Conway, Kelly, Lin, Yin-Guo, Gillespie, Patrick J., Bokvist, Krister B., Attardo, Giorgio, Kahn, Steven E., Scheuner, Donalyn, Hull, Rebecca L.

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