Search Results - "Boknäs, N."

PO-55 - Individual variation in hemostatic alterations caused by tyrosine kinase inhibitors – a way to improve personalized cancer therapy? by Deb, S, Sjöström, C, Tharmakulanathan, A, Boknäs, N, Lotfi, K, Ramström, S

“…Introduction During the last two decades, Bcr-Abl tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myelogenous leukemia (CML),…”
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Scanning laser-induced endothelial injury: a standardized and reproducible thrombosis model for intravital microscopy by Larsson, P., Tarlac, V., Wang, T.-Y., Bonnard, T., Hagemeyer, C. E., Hamilton, J. R., Medcalf, R. L., Cody, S. H., Boknäs, N.

“…Vascular injury models are indispensable for studying thrombotic processes in vivo. Amongst the available methods for inducing thrombosis, laser-induced…”
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Contact activation: important to consider when measuring the contribution of tissue factor‐bearing microparticles to thrombin generation using phospholipid‐containing reagents by Boknäs, N., Faxälv, L., Lindahl, T. L., Ramström, S.

“…Summary Background A commercial MP reagent containing phospholipids is used for thrombin generation (TG) measurements to estimate the procoagulant activity of…”
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Individual variation in hemostatic alterations caused by tyrosine kinase inhibitors: a way to improve personalized cancer therapy? by Deb, S., Sjöström, C., Tharmakulanathan, A., Boknäs, N., Lotfi, K., Ramström, Sofia

“…INTRODUCTION: During the last two decades, Bcr-Abl tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myelogenous leukemia (CML),…”
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Thrombin generation in plasma measured with a commercial reagent for the detection of microparticle-derived tissue factor is heavily influenced by contact activation by Boknäs, N., Faxälv, L., Ramström, Sofia, Lindahl, T.

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Thrombin-induced platelet activation via PAR4: pivotal role for exosite II by Boknäs, N, Faxälv, L, Sanchez Centellas, D, Wallstedt, M, Ramström, S, Grenegård, M, Lindahl, T L

“…Thrombin-induced platelet activation via PAR1 and PAR4 is an important event in haemostasis. Although the underlying mechanisms responsible for ensuring…”
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Gradient-dependent Modulation of Platelet Stimulatory G-protein Coupled Receptors (GPCR) Signaling by Macwan, A., Boknäs, N., Ramström, Sofia, Berg, S., Faxälv, L., Lindahl, T.

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Systematically Perturbed Folding Patterns of Amyotrophic Lateral Sclerosis (ALS)-Associated SOD1 Mutants by Lindberg, Mikael J., Byström, Roberth, Boknäs, Niklas, Andersen, Peter M., Oliveberg, Mikael, Fersht, Alan R.

“…Amyotrophic lateral sclerosis is a neurodegenerative syndrome associated with 114 mutations in the gene encoding the cytosolic homodimeric enzyme Cu/Zn…”
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