Search Results - "Bokde, A L W"
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Functional connectivity of the fusiform gyrus during a face-matching task in subjects with mild cognitive impairment
Published in Brain (London, England : 1878) (01-05-2006)“…Cognitive function requires a high level of functional interaction between regions of a network supporting cognition. Assuming that brain activation changes…”
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Effects of aging on default mode network activity in resting state fMRI: Does the method of analysis matter?
Published in NeuroImage (Orlando, Fla.) (15-05-2010)“…Functional MRI (fMRI) of default mode network (DMN) brain activity during resting state is gaining attention as a potential non-invasive biomarker to diagnose…”
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3
Single nucleotide polymorphism in the neuroplastin locus associates with cortical thickness and intellectual ability in adolescents
Published in Molecular psychiatry (01-02-2015)“…Despite the recognition that cortical thickness is heritable and correlates with intellectual ability in children and adolescents, the genes contributing to…”
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4
On the development of markers for pathological TDP-43 in amyotrophic lateral sclerosis with and without dementia
Published in Progress in neurobiology (01-12-2011)“…Pathological 43-kDa transactive response sequence DNA-binding protein (TDP-43) has been recognized as the major disease protein in amyotrophic lateral…”
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Age-dependent differences in human brain activity using a face- and location-matching task: an FMRI study
Published in Dementia and geriatric cognitive disorders (01-01-2007)“…To evaluate the differences of cortical activation patterns in young and elderly healthy subjects for object and spatial visual processing using a face- and…”
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BDNF Val66Met and reward-related brain function in adolescents: Role for early alcohol consumption
Published in Alcohol (Fayetteville, N.Y.) (01-03-2015)“…Abstract Changes in reward processing have been identified as one important pathogenetic mechanism in alcohol addiction. The nonsynonymous single nucleotide…”
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7
Interaction between striatal volume and DAT1 polymorphism predicts working memory development during adolescence
Published in Developmental cognitive neuroscience (01-04-2018)“…There is considerable inter-individual variability in the rate at which working memory (WM) develops during childhood and adolescence, but the neural and…”
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The use of neuroimaging in dementia by Irish general practitioners
Published in Irish journal of medical science (01-08-2016)“…Background More than 48,000 people in Ireland are living with dementia, and the number is likely to rise to 130,000 by 2041. Dementia frequently remains…”
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Structural and functional neuronal connectivity in Alzheimer's disease: a combined DTI and fMRI study
Published in Nervenarzt (01-07-2012)“…Cognitive performance depends on intact cortical connectivity. Important for memory processing in the human brain is the connection between posterior cingulate…”
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Regional pattern of hippocampus and corpus callosum atrophy in Alzheimer’s disease in relation to dementia severity: evidence for early neocortical degeneration
Published in Neurobiology of aging (01-01-2003)“…We used volumetric MRI and analysis of areas under receiver operating characteristic (ROC) curves to directly compare the extent of hippocampus–amygdala…”
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Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease
Published in Dementia and geriatric cognitive disorders (01-01-2005)“…Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). We hypothesized…”
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A new rapid landmark-based regional MRI segmentation method of the brain
Published in Journal of the neurological sciences (15-02-2002)“…Background: Neurodegenerative and cerebrovascular diseases show a distinct distribution of regional atrophy and subcortical lesions. Objective: To develop an…”
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13
Task difficulty in a simultaneous face matching task modulates activity in face fusiform area
Published in Brain research. Cognitive brain research (01-12-2005)“…The level of difficulty of a task can alter the neural network that activates for performance of the task. Previous studies have shown increased activation…”
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14
Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease
Published in Alzheimer's & dementia (01-06-2019)“…Blood-based biomarkers of pathophysiological brain amyloid β (Aβ) accumulation, particularly for preclinical target and large-scale interventions, are…”
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15
Cognitive and brain development is independently influenced by socioeconomic status and polygenic scores for educational attainment
Published in Proceedings of the National Academy of Sciences - PNAS (02-06-2020)“…Genetic factors and socioeconomic status (SES) inequalities play a large role in educational attainment, and both have been associated with variations in brain…”
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Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers
Published in Neurobiology of aging (01-12-2020)“…Neuroinflammation, a key early pathomechanistic alteration of Alzheimer’s disease, may represent either a detrimental or a compensatory mechanism or both…”
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EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction
Published in Molecular psychiatry (01-05-2018)“…In many societies, the majority of adults regularly consume alcohol. However, only a small proportion develops alcohol addiction. Individuals at risk often…”
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Evolving Evidence for the Value of Neuroimaging Methods and Biological Markers in Subjects Categorized with Subjective Cognitive Decline
Published in Journal of Alzheimer's disease (24-09-2015)“…There is evolving evidence that individuals categorized with subjective cognitive decline (SCD) are potentially at higher risk for developing objective and…”
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The Arf6 activator Efa6/PSD3 confers regional specificity and modulates ethanol consumption in Drosophila and humans
Published in Molecular psychiatry (01-03-2018)“…Ubiquitously expressed genes have been implicated in a variety of specific behaviors, including responses to ethanol. However, the mechanisms that confer this…”
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Morphological substrate of face matching in healthy ageing and mild cognitive impairment: a combined MRI-fMRI study
Published in Brain (London, England : 1878) (01-07-2007)“…Functional MRI during face matching shows activation of the ventral visual stream, including the ventral temporal lobes and fusiform gyrus. In contrast, a…”
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