Search Results - "Bokarewa, Maria"

Resistin competes with lipopolysaccharide for binding to toll‐like receptor 4 by Tarkowski, Andrej, Bjersing, Jan, Shestakov, Andrey, Bokarewa, Maria I.

“…Toll‐like receptors (TLRs) are a family of cellular structures activated by recognition of pathogen associated molecular sequences. The activation of TLRs…”
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Profile of cerebrospinal microRNAs in fibromyalgia by Bjersing, Jan L, Lundborg, Christopher, Bokarewa, Maria I, Mannerkorpi, Kaisa

“…Fibromyalgia (FM) is characterized by chronic pain and reduced pain threshold. The pathophysiology involves disturbed neuroendocrine function, including…”
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Aberrant expression of USF2 in refractory rheumatoid arthritis and its regulation of proinflammatory cytokines in Th17 cells by Hu, Dan, Tjon, Emily C., Andersson, Karin M., Molica, Gabriela M., Pham, Minh C., Healy, Brian, Murugaiyan, Gopal, Pochet, Nathalie, Kuchroo, Vijay K., Bokarewa, Maria I., Weiner, Howard L.

“…IL-17–producing Th17 cells are implicated in the pathogenesis of rheumatoid arthritis (RA) and TNF-α, a proinflammatory cytokine in the rheumatoid joint,…”
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Profile of circulating microRNAs in fibromyalgia and their relation to symptom severity: an exploratory study by Bjersing, Jan L., Bokarewa, Maria I., Mannerkorpi, Kaisa

“…Fibromyalgia (FM) is characterized by generalized chronic pain and reduced pain thresholds. Disturbed neuroendocrine function and impairment of growth…”
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Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis by Andersson, Karin M. E., Wasén, Caroline, Juzokaite, Lina, Leifsdottir, Lovisa, Erlandsson, Malin C., Silfverswärd, Sofia T., Stokowska, Anna, Pekna, Marcela, Pekny, Milos, Olmarker, Kjell, Heckemann, Rolf A., Kalm, Marie, Bokarewa, Maria I.

“…Rheumatoid arthritis (RA) is an inflammatory joint disease with a neurological component including depression, cognitive deficits, and pain, which…”
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Bone remodelling: locus minori or unappreciated potential of tofacitinib? by Bokarewa, Maria I, Erlandsson, Malin C

“…This editorial refers to the article "Effects of tofacitinib in early arthritis-induced bone loss in an adjuvant-induced arthritis rat model" by Bruno Vidal et…”
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Short- and long-term effects of anti-CD20 treatment on B cell ontogeny in bone marrow of patients with rheumatoid arthritis by Rehnberg, Maria, Amu, Sylvie, Tarkowski, Andrej, Bokarewa, Maria I, Brisslert, Mikael

“…In the present study we evaluated changes in the B cell phenotype in peripheral blood and bone marrow (BM) of patients with rheumatoid arthritis (RA) following…”
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Prognostic Significance of BIRC5/Survivin in Breast Cancer: Results from Three Independent Cohorts by Oparina, Nina, Erlandsson, Malin C., Fäldt Beding, Anna, Parris, Toshima, Helou, Khalil, Karlsson, Per, Einbeigi, Zakaria, Bokarewa, Maria I.

“…Breast cancer (BC) histological and molecular classifications significantly improved the treatment strategy and prognosis. Inhibitor of apoptosis…”
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IGF-1R signalling contributes to IL-6 production and T cell dependent inflammation in rheumatoid arthritis by Erlandsson, Malin C., Töyrä Silfverswärd, Sofia, Nadali, Mitra, Turkkila, Minna, Svensson, Mattias N.D., Jonsson, Ing-Marie, Andersson, Karin M.E., Bokarewa, Maria I.

“…Signalling through insulin-like growth factor 1 receptor (IGF-1R) is essential for cell survival, but may turn pathogenic in uncontrolled tissue growth in…”
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Bivalent chromatin accommodates survivin and BRG1/SWI complex to activate DNA damage response in CD4 + cells by Chandrasekaran, Venkataragavan, Andersson, Karin M E, Erlandsson, Malin, Li, Shuxiang, Olsson, Torbjörn Nur, Garcia-Bonete, Maria-Jose, Malmhäll-Bah, Eric, Johansson, Pegah, Katona, Gergely, Bokarewa, Maria I

“…Bivalent regions of chromatin (BvCR) are characterized by trimethylated lysine 4 (H3K4me3) and lysine 27 on histone H3 (H3K27me3) deposition which aid gene…”
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Radiological features of experimental staphylococcal septic arthritis by micro computed tomography scan by Fatima, Farah, Fei, Ying, Ali, Abukar, Mohammad, Majd, Erlandsson, Malin C, Bokarewa, Maria I, Nawaz, Muhammad, Valadi, Hadi, Na, Manli, Jin, Tao

“…Permanent joint dysfunction due to bone destruction occurs in up to 50% of patients with septic arthritis. Recently, imaging technologies such as micro…”
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Metabolic signature and proteasome activity controls synovial migration of CDC42hiCD14+ cells in rheumatoid arthritis by Malmhäll-Bah, Eric, Andersson, Karin M.E., Erlandsson, Malin C., Silfverswärd, Sofia T., Pullerits, Rille, Bokarewa, Maria I.

“…Objective Activation of Rho-GTPases in macrophages causes inflammation and severe arthritis in mice. In this study, we explore if Rho-GTPases define the joint…”
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Chronic hyperinsulinemia promotes human hepatocyte senescence by Baboota, Ritesh K., Spinelli, Rosa, Erlandsson, Malin C., Brandao, Bruna B., Lino, Marsel, Yang, Hong, Mardinoglu, Adil, Bokarewa, Maria I., Boucher, Jeremie, Kahn, C. Ronald, Smith, Ulf

“…Cellular senescence, an irreversible proliferative cell arrest, is caused by excessive intracellular or extracellular stress/damage. Increased senescent cells…”
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IGF1R signalling is a guardian of self-tolerance restricting autoantibody production by Erlandsson, Malin C., Erdogan, Seval, Wasén, Caroline, Andersson, Karin M. E., Silfverswärd, Sofia T., Pullerits, Rille, Bemark, Mats, Bokarewa, Maria I.

“…Objective Insulin-like growth factor 1 receptor (IGF1R) acts at the crossroad between immunity and cancer, being an attractive therapeutic target in these…”
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Low serum IGF1 is associated with hypertension and predicts early cardiovascular events in women with rheumatoid arthritis by Erlandsson, Malin C, Lyngfelt, Lovisa, Åberg, N David, Wasén, Caroline, Espino, Rachelle A, Silfverswärd, Sofia Töyrä, Nadali, Mitra, Jood, Katharina, Andersson, Karin M E, Pullerits, Rille, Bokarewa, Maria I

“…Since low insulin-like growth factor (IGF) 1 is often linked to inflammation, we analyze whether serum levels of IGF1 are associated with cardiovascular…”
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A unique population of IgG-expressing plasma cells lacking CD19 is enriched in human bone marrow by Mei, Henrik E., Wirries, Ina, Frölich, Daniela, Brisslert, Mikael, Giesecke, Claudia, Grün, Joachim R., Alexander, Tobias, Schmidt, Stefanie, Luda, Katarzyna, Kühl, Anja A., Engelmann, Robby, Dürr, Michael, Scheel, Tobias, Bokarewa, Maria, Perka, Carsten, Radbruch, Andreas, Dörner, Thomas

“…Specific serum antibodies mediating humoral immunity and autoimmunity are provided by mature plasma cells (PC) residing in the bone marrow (BM), yet their…”
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Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis by Hu, Dan, Notarbartolo, Samuele, Croonenborghs, Tom, Patel, Bonny, Cialic, Ron, Yang, Tun-Hsiang, Aschenbrenner, Dominik, Andersson, Karin M., Gattorno, Marco, Pham, Minh, Kivisakk, Pia, Pierre, Isabelle V., Lee, Youjin, Kiani, Karun, Bokarewa, Maria, Tjon, Emily, Pochet, Nathalie, Sallusto, Federica, Kuchroo, Vijay K., Weiner, Howard L.

“…We have previously reported the molecular signature of murine pathogenic T H 17 cells that induce experimental autoimmune encephalomyelitis (EAE) in animals…”
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The tumour-associated glycoprotein podoplanin is expressed in fibroblast-like synoviocytes of the hyperplastic synovial lining layer in rheumatoid arthritis by Ekwall, Anna-Karin H, Eisler, Thomas, Anderberg, Christian, Jin, Chunsheng, Karlsson, Niclas, Brisslert, Mikael, Bokarewa, Maria I

“…Activated fibroblast-like synoviocytes (FLSs) in rheumatoid arthritis (RA) share many characteristics with tumour cells and are key mediators of synovial…”
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MicroRNA and interleukin 6 interplay in the adipose tissue of rheumatoid arthritis patients by Larsson, Carolina, Andersson, Karin M E, Nadali, Mitra, Silfverswärd, Sofia T, Bokarewa, Maria I, Erlandsson, Malin C

“…MicroRNAs (miRs) are non-translated RNA sequences that elicit negative control over protein expression. The adipose tissue (AT) is considered the major…”
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Human resistin is a systemic immune-derived proinflammatory cytokine targeting both leukocytes and adipocytes by Nagaev, Ivan, Bokarewa, Maria, Tarkowski, Andrej, Smith, Ulf

“…The characteristics of human resistin (RETN) are unclear and controversial despite intensive adipose-focused research. Its transcriptional and functional…”
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