Search Results - "Bojesen, S E"

Telomeres and human health by Bojesen, S. E.

“…Telomeres are the tips of chromosomes and consist of proteins and hexanucleotide tandem repeats of DNA. The DNA repeats are shortened at each mitotic division…”
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Plasma testosterone in the general population, cancer prognosis and cancer risk: a prospective cohort study by Ørsted, D.D, Nordestgaard, B.G., Bojesen, S.E.

“…Testosterone is an important anabolic hormone in humans and in vitro testosterone stimulates growth of lung and colon cancer cells. We tested the hypothesis…”
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Cancer risk by combined levels of YKL-40 and C-reactive protein in the general population by Allin, K H, Bojesen, S E, Johansen, J S, Nordestgaard, B G

“…Background: YKL-40 and C-reactive protein (CRP) are biomarkers that may reflect cancer-related subclinical inflammation. We assessed elevated YKL-40 and CRP…”
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Asthma, other atopic conditions and risk of infections in 105 519 general population never and ever smokers by Helby, J., Nordestgaard, B. G., Benfield, T., Bojesen, S. E.

“…Background Individuals with atopic conditions may have increased susceptibility to infections outside the organs directly affected by their atopic condition…”
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Characterisation of the GRAF gene promoter and its methylation in patients with acute myeloid leukaemia and myelodysplastic syndrome by BOJESEN, S. E, AMMERPOHL, O, WEINHÄUSL, A, HAAS, O. A, METTAL, H, BOHLE, R. M, BORKHARDT, A, FUCHS, U

“…We report the isolation of the 5' flanking region of GRAF (GTPase regulator associated with the focal adhesion kinase), previously described as a putative…”
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IgE and risk of cancer in 37 747 individuals from the general population by Helby, J., Bojesen, S.E., Nielsen, S.F., Nordestgaard, B.G.

“…Immunoglobulin E (IgE) is produced by plasma cells, often as part of an allergic immune response. It is currently unknown whether plasma IgE levels are…”
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Role of inflammatory marker YKL-40 in the diagnosis, prognosis and cause of cardiovascular and liver diseases by Kjaergaard, A. D., Johansen, J. S., Bojesen, S. E., Nordestgaard, B. G.

“…This review summarizes present evidence for the role of YKL-40 in the diagnosis, prognosis and cause of cardiovascular and alcoholic liver disease. The…”
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Elevated plasma YKL-40 and risk of infectious disease: a prospective study of 94665 individuals from the general population by Kjaergaard, A.D., Helby, J., Johansen, J.S., Nordestgaard, B.G., Bojesen, S.E.

“…YKL-40 is an acute phase protein elevated in patients with infectious and inflammatory diseases. We tested the hypothesis that baseline elevated YKL-40 is…”
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JAK2V617F somatic mutation in the general population: myeloproliferative neoplasm development and progression rate by Nielsen, Camilla, Bojesen, Stig E, Nordestgaard, Børge G, Kofoed, Klaus F, Birgens, Henrik S

“…Clinical significance of the JAK2V617F mutation in patients with a myeloproliferative neoplasm has been the target of intensive research in recent years…”
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Common breast cancer risk alleles and risk assessment: a study on 35 441 individuals from the Danish general population by Näslund-Koch, C., Nordestgaard, B.G., Bojesen, S.E.

“…We hypothesized that common breast cancer risk alleles are associated with incidences of breast cancer and other cancers in the general population, and…”
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The JAK2 V617F somatic mutation, mortality and cancer risk in the general population by Nielsen, Camilla, Birgens, Henrik S, Nordestgaard, Børge G, Kjaer, Lasse, Bojesen, Stig E

“…JAK2 V617F is present in the majority of patients with myeloproliferative cancer; however, its prevalence and clinical significance in the general population…”
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No association of breast cancer risk with integrin beta3 (ITGB3) Leu33Pro genotype by BOJESEN, S. E, TYBJAERG-HANSEN, A, AXELSSON, C. K, NORDESTGAARD, B. G

“…To pursue a borderline increased risk of breast cancer for carriers of two integrin beta(3) (ITGB3) 33Pro alleles found in a recent prospective study, we…”
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Clinical utility of plasma cell-free DNA in patients with pancreatic cancer by Chen, I., Wind, K.L., Dehlendorff, C., Sørensen, B.S., Vittrup, B.V., Johansen, A., Pfeiffer, P., Bjerregaard, J.K., Bojesen, S.E., Nielsen, S.E., Holländer, N.H., Yilmaz, M.K., Rasmussen, L.S., Pallisgaard, N., Johansen, J.S., Spindler, K.-L.G.

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Clinical utility of serum type III collagen in patients with pancreatic carcinoma by Chen, I., Willumsen, N., Dehlendorff, C., Johansen, A., Vittrup, B.V., Krüger, M., Pfeiffer, P., Bjerregaard, J.K., Bojesen, S.E., Nielsen, S.E., Holländer, N.H., Yilmaz, M.K., Rasmussen, L.S., Karsdal, M., Johansen, J.S.

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Increased risk of ovarian cancer in integrin β3 Leu33Pro homozygotes by Bojesen, S E, Kjær, S K, Høgdall, E V S, Thomsen, B L, Høgdall, C K, Blaakær, J, Tybjærg-Hansen, A, Nordestgaard, B G

“…We previously demonstrated that integrin β3 Leu33Pro homozygotes have an increased risk of cancer, possibly most pronounced for ovarian cancer. We now test the…”
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Elevated rheumatoid factor and long term risk of rheumatoid arthritis: a prospective cohort study by Nielsen, Sune F, Bojesen, Stig E, Schnohr, Peter, Nordestgaard, Børge G

“…Objective To test whether elevated concentration of rheumatoid factor is associated with long term development of rheumatoid arthritis.Design A prospective…”
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Copy number variation in glutathione-S-transferase T1 and M1 predicts incidence and 5-year survival from prostate and bladder cancer, and incidence of corpus uteri cancer in the general population by Nørskov, M S, Frikke-Schmidt, R, Bojesen, S E, Nordestgaard, B G, Loft, S, Tybjærg-Hansen, A

“…Glutathione- S -transferase T1 (GSTT1) and GSTM1 detoxify carcinogens and thus potentially contribute to inter-individual susceptibility to cancer. We…”
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Common polymorphisms in CYP2C9, subclinical atherosclerosis and risk of ischemic vascular disease in 52000 individuals by Kaur-Knudsen, D, Bojesen, S E, Nordestgaard, B G

“…Cytochrome P450 2C9 (CYP2C9) enzymes metabolize warfarin and arachidonic acid. We hypothesized that the CYP2C9 super(*)2 (rs.1799853) and CYP2C9 super(*)3…”
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Common polymorphisms in CYP2C9, subclinical atherosclerosis and risk of ischemic vascular disease in 52 000 individuals by Kaur-Knudsen, D, Bojesen, S E, Nordestgaard, B G

“…Cytochrome P450 2C9 (CYP2C9) enzymes metabolize warfarin and arachidonic acid. We hypothesized that the CYP2C9 * 2 (rs.1799853) and CYP2C9 * 3 (rs.1057910)…”
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Genetically low vitamin D concentrations and increased mortality: mendelian randomisation analysis in three large cohorts by Afzal, Shoaib, Brøndum-Jacobsen, Peter, Bojesen, Stig E, Nordestgaard, Børge G

“…Objective To test the hypothesis that genetically low 25-hydroxyvitamin D concentrations are associated with increased mortality. Design Mendelian…”
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