Search Results - "Bojesen, Kirsten B"
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Add-On MEmaNtine to Dopamine Antagonism to Improve Negative Symptoms at First Psychosis- the AMEND Trial Protocol
Published in Frontiers in psychiatry (20-05-2022)“…Antipsychotic drugs are primarily efficacious in treating positive symptoms by blocking the dopamine D2 receptor, but they fail to substantially improve…”
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Structural and functional connectivity in relation to executive functions in antipsychotic-naïve patients with first episode schizophrenia
Published in NPJ schizophrenia (31-08-2024)“…Patients with schizophrenia exhibit structural and functional dysconnectivity but the relationship to the well-documented cognitive impairments is less clear…”
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Nectin-1 Binds and Signals through the Fibroblast Growth Factor Receptor
Published in The Journal of biological chemistry (26-10-2012)“…Nectins belong to a family of immunoglobulin (Ig)-like cell-adhesion molecules comprising four members, nectin-1 through nectin-4. Nectins are involved in…”
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Influence of psychopathology and metabolic parameters on quality of life in patients with first-episode psychosis before and after initial antipsychotic treatment
Published in NPJ schizophrenia (07-11-2023)“…The impact of psychological and physical health on quality of life (QoL) in patients with early psychosis remain relatively unexplored. We evaluated the…”
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Treatment response after 6 and 26 weeks is related to baseline glutamate and GABA levels in antipsychotic-naïve patients with psychosis
Published in Psychological medicine (01-10-2020)“…Poor response to dopaminergic antipsychotics constitutes a major challenge in the treatment of psychotic disorders and markers for non-response during…”
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Reward disturbances in antipsychotic-naïve patients with first-episode psychosis and their association to glutamate levels
Published in Psychological medicine (01-03-2023)“…Aberrant anticipation of motivational salient events and processing of outcome evaluation in striatal and prefrontal regions have been suggested to underlie…”
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Cognitive profiles across the psychosis continuum
Published in Psychiatry research (01-12-2024)“…•The translation of research findings on cognitive functioning into personalized treatment planning for patients within the psychosis spectrum is…”
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Glycocalyx shedding patterns identifies antipsychotic-naïve patients with first-episode psychosis
Published in Psychiatry research (01-09-2024)“…·Need for biomarkers to help diagnose psychosis spectrum disorders at earlier stages.·Indication of dysfunctional blood brain barrier in acute…”
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Fibre density and fibre-bundle cross-section of the corticospinal tract are distinctly linked to psychosis-specific symptoms in antipsychotic-naïve patients with first-episode schizophrenia
Published in European archives of psychiatry and clinical neuroscience (01-12-2023)“…Multiple lines of research support the dysconnectivity hypothesis of schizophrenia. However, findings on white matter (WM) alterations in patients with…”
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Clustering of antipsychotic-naïve patients with schizophrenia based on functional connectivity from resting-state electroencephalography
Published in European archives of psychiatry and clinical neuroscience (01-12-2023)“…Schizophrenia is associated with aberrations in the Default Mode Network (DMN), but the clinical implications remain unclear. We applied data-driven,…”
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Prediction of Early Symptom Remission in Two Independent Samples of First-Episode Psychosis Patients Using Machine Learning
Published in Schizophrenia bulletin (21-01-2022)“…Abstract Background Validated clinical prediction models of short-term remission in psychosis are lacking. Our aim was to develop a clinical prediction model…”
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Scalability of the Positive and Negative Syndrome Scale in first‐episode schizophrenia assessed by Rasch models
Published in Acta psychiatrica Scandinavica (01-07-2022)“…Objective Historically, assessment of the psychometric properties of the Positive and Negative Syndrome Scale (PANSS) has had several foci: (1) calculation of…”
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Structural and functional connectivity in relation to executive functions in antipsychotic-naïve patients with first episode schizophrenia and levels of glutamatergic metabolites
Published in Schizophrenia (Heidelberg, Germany) (31-08-2024)“…Patients with schizophrenia exhibit structural and functional dysconnectivity but the relationship to the well-documented cognitive impairments is less clear…”
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Patterns of Cortical Structures and Cognition in Antipsychotic-Naïve Patients With First-Episode Schizophrenia: A Partial Least Squares Correlation Analysis
Published in Biological psychiatry : cognitive neuroscience and neuroimaging (01-05-2019)“…Schizophrenia is associated with alterations in cortical structures and cognitive impairments, but antipsychotic medication may affect these measures. We…”
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Corrigendum to: Prediction of Early Symptom Remission in Two Independent Samples of First-Episode Psychosis Patients Using Machine Learning
Published in Schizophrenia bulletin (21-01-2022)Get full text
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