Search Results - "Bojarska, Joanna"
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Advances in Research of Short Peptides
Published in Molecules (Basel, Switzerland) (11-04-2022)“…Short peptides are unique biomolecules, which combine the advantages of classical small molecules and mature proteins and have attracted increasing interest…”
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Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity: A Mini-Review
Published in Molecules (Basel, Switzerland) (05-07-2022)“…The prevalence of obesity and diabetes is an increasing global problem, especially in developed countries, and is referred to as the twin epidemics. As such,…”
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A Global Review on Short Peptides: Frontiers and Perspectives
Published in Molecules (Basel, Switzerland) (15-01-2021)“…Peptides are fragments of proteins that carry out biological functions. They act as signaling entities via all domains of life and interfere with…”
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Peptide-Drug Conjugates: A New Hope for Cancer Management
Published in Molecules (Basel, Switzerland) (25-10-2022)“…Cancer remains the leading cause of death worldwide despite advances in treatment options for patients. As such, safe and effective therapeutics are required…”
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A Supramolecular Approach to Structure-Based Design with A Focus on Synthons Hierarchy in Ornithine-Derived Ligands: Review, Synthesis, Experimental and in Silico Studies
Published in Molecules (Basel, Switzerland) (03-03-2020)“…The success of innovative drugs depends on an interdisciplinary and holistic approach to their design and development. The supramolecular architecture of…”
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Smart therapies against global pandemics: A potential of short peptides
Published in Frontiers in pharmacology (15-08-2022)Get full text
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Novel Salts of Heterocyclic Polyamines and 5-Sulfosalicylic Acid: Synthesis, Crystal Structure, and Hierarchical Supramolecular Interactions
Published in Crystals (Basel) (01-06-2024)“…A series of novel salts of heterocyclic polyamines with 5-sulfosalicylic acid (C4H7N4+)(C7H5O6S−)∙2(H2O) (1), (C4H6ClN4+)(C7H5O6S−)∙H2O (2),…”
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Synthesis, Crystal Structure and Supramolecular Features of Novel 2,4-Diaminopyrimidine Salts
Published in Crystals (Basel) (01-01-2024)“…The crystal structures and the supramolecular architectures of a series of novel salts originating from 2,4-diaminopyrimidine and four different chain…”
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Antibody-Biopolymer Conjugates in Oncology: A Review
Published in Molecules (Basel, Switzerland) (01-03-2023)“…Cancer is one of the most prevalent diseases and affects a large proportion of the population worldwide. Conventional treatments in the management include…”
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Bioactive Peptide Discovery from Edible Insects for Potential Applications in Human Health and Agriculture
Published in Molecules (Basel, Switzerland) (27-01-2023)“…In the past decade, there has been fast-growing interest among researchers to discover bioactive peptides from edible insects and to evaluate their potential…”
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Recurrent Supramolecular Patterns in a Series of Salts of Heterocyclic Polyamines and Heterocyclic Dicarboxylic Acids: Synthesis, Single-Crystal X-ray Structure, Hirshfeld Surface Analysis, Energy Framework, and Quantum Chemical Calculations
Published in Crystals (Basel) (01-08-2024)“…A series of novel salts based on aromatic polyamines and 2,3-pyrazinedicarboxylic acid, such as C[sub.10]H[sub.12]N[sub.6]O[sub.5] (1),…”
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Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin System
Published in Molecules (Basel, Switzerland) (29-07-2022)“…Angiotensin receptor blockers (ARBs) used in the treatment of hypertension and potentially in SARS-CoV-2 infection exhibit inverse agonist effects at…”
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Structural and Biofunctional Insights into the Cyclo(Pro-Pro-Phe-Phe-) Scaffold from Experimental and In Silico Studies: Melanoma and Beyond
Published in International journal of molecular sciences (01-07-2022)“…Short peptides have great potential as safe and effective anticancer drug leads. Herein, the influence of short cyclic peptides containing the Pro-Pro-Phe-Phe…”
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New Advances in Short Peptides: Looking Forward
Published in Molecules (Basel, Switzerland) (06-06-2022)“…It is beyond doubt that short peptides hold significant promise in bio-medicine, as the most versatile molecules, both structurally and functionally [...]…”
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Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold
Published in Biomolecules (Basel, Switzerland) (14-10-2021)“…Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of peptides widespread in nature, are unsurpassed in their structural and…”
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LIFE CYCLE ASSESSMENT AS TOOL FOR REALIZATION OF SUSTAINABLE DEVELOPMENT GOALS - TOWARDS SUSTAINABLE FUTURE OF THE WORLD: MINI REVIEW
Published in Acta Innovations (01-03-2021)“…“One planet, one main goal: good life for all”: it could be a motto of sustainable world. Sustainability is global mega trend in all fields of life to promote…”
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A Proline-Based Tectons and Supramolecular Synthons for Drug Design 2.0: A Case Study of ACEI
Published in Pharmaceuticals (Basel, Switzerland) (24-10-2020)“…Proline is a unique, endogenous amino acid, prevalent in proteins and essential for living organisms. It is appreciated as a tecton for the rational design of…”
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The Immunosuppressive Properties of Cyclo-[ D -Pro-Pro- β 3 -HoPhe-Phe-] Tetrapeptide Selected from Stereochemical Variants of Cyclo-[Pro-Pro- β 3 -HoPhe-Phe-] Peptide
Published in Pharmaceutics (22-08-2024)“…The anti-inflammatory, antiviral, and anti-cancer properties, as well as the mechanism of action of cyclo-[Pro-Pro- -HoPhe-Phe-] tetrapeptide (denoted as…”
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An experimental and computational investigation of the cyclopentene-containing peptide-derived compounds: focus on pseudo-cyclic motifs via intramolecular interactions
Published in Royal Society open science (01-10-2024)“…Conformational flexibility is one of the main disadvantages of peptide-based compounds. We focus on their molecular 'chameleonicity' related to forming…”
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Antimicrobial Photodynamic Therapy against Escherichia coli and Staphylococcus aureus Using Nanoemulsion-Encapsulated Zinc Phthalocyanine
Published in Microorganisms (Basel) (27-04-2023)“…Multidrug-resistant microorganisms have become a significant public health threat, and traditional antibiotics are becoming ineffective. Photodynamic therapy…”
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