Search Results - "Bojang, Fatoumata"
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Stepwise in vitro screening of MMV pathogen box compounds against Plasmodium falciparum to identify potent antimalarial candidates
Published in International journal for parasitology -- drugs and drug resistance (01-08-2023)“…Development of resistance to deployed antimalarial drugs is inevitable and needs prompt and continuous discovery of novel candidate drugs. Therefore, the…”
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Recent increase in low complexity polygenomic infections and sialic acid-independent invasion pathways in Plasmodium falciparum from Western Gambia
Published in Parasites & vectors (31-08-2023)“…Abstract Background The malaria parasite Plasmodium falciparum utilizes multiple alternative receptor-ligand interactions for the invasion of human…”
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Transcriptome analysis reveals molecular targets of erythrocyte invasion phenotype diversity in natural Plasmodium falciparum isolates from Cameroon
Published in Frontiers in parasitology (24-05-2024)“…Further understanding of the molecular mediators of alternative RBC invasion phenotypes in endemic malaria parasites will support malaria blood-stage vaccine…”
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Plasmodium falciparum merozoite invasion ligands, linked antimalarial resistance loci and ex vivo responses to antimalarials in The Gambia
Published in Journal of antimicrobial chemotherapy (28-10-2022)“…Artemether/lumefantrine is the most commonly used artemisinin-based combination treatment (ACT) for malaria in sub-Saharan Africa. Drug resistance to ACT…”
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Tolerance of Gambian Plasmodium falciparum to Dihydroartemisinin and Lumefantrine Detected by Ex Vivo Parasite Survival Rate Assay
Published in Antimicrobial agents and chemotherapy (16-12-2020)“…Monitoring of sensitivity to antimalarial drugs in Africa is vital for malaria elimination. However, the commonly used / 50% inhibitory concentration (IC )…”
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A modified two-color flow cytometry assay to quantify in-vitro reinvasion and determine invasion phenotypes at low Plasmodium falciparum parasitemia
Published in Experimental parasitology (01-11-2020)“…Invasion of human red blood cells (RBCs) by Plasmodium parasites is a crucial yet poorly characterised phenotype. Two-color flow cytometry (2cFCM) promises to…”
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