Search Results - "Boix, Ester"

Immune Modulation by Human Secreted RNases at the Extracellular Space by Lu, Lu, Li, Jiarui, Moussaoui, Mohammed, Boix, Ester

“…The ribonuclease A superfamily is a vertebrate-specific family of proteins that encompasses eight functional members in humans. The proteins are secreted by…”
Get full text

Host Defence RNases as Antiviral Agents against Enveloped Single Stranded RNA Viruses by Li, Jiarui, Boix, Ester

“…Owing to the recent outbreak of Coronavirus Disease of 2019 (COVID-19), it is urgent to develop effective and safe drugs to treat the present pandemic and…”
Get full text

Synergism between Host Defence Peptides and Antibiotics Against Bacterial Infections by Li, Jiarui, Fernández-Millán, Pablo, Boix, Ester

“…Antimicrobial resistance (AMR) to conventional antibiotics is becoming one of the main global health threats and novel alternative strategies are urging…”
Get more information

Selective cleavage of ncRNA and antiviral activity by RNase2/EDN in THP1-induced macrophages by Lu, Lu, Li, Jiarui, Wei, Ranlei, Guidi, Irene, Cozzuto, Luca, Ponomarenko, Julia, Prats-Ejarque, Guillem, Boix, Ester

“…RNase2 is the member of the RNaseA family most abundant in macrophages. Here, we knocked out RNase2 in THP-1 cells and analysed the response to Respiratory…”
Get full text

Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model by Lu, Lu, Wei, RanLei, Prats-Ejarque, Guillem, Goetz, Maria, Wang, Gang, Torrent, Marc, Boix, Ester

“…The human RNase3 is a member of the RNaseA superfamily involved in host immunity. RNase3 is expressed by leukocytes and shows broad-spectrum antimicrobial…”
Get full text

Host Antimicrobial Peptides: The Promise of New Treatment Strategies against Tuberculosis by Arranz-Trullén, Javier, Lu, Lu, Pulido, David, Bhakta, Sanjib, Boix, Ester

“…Tuberculosis (TB) continues to be a devastating infectious disease and remerges as a global health emergency due to an alarming rise of antimicrobial…”
Get full text

A Common Polymorphism in RNASE6 Impacts Its Antimicrobial Activity toward Uropathogenic Escherichia coli by Anguita, Raul, Prats-Ejarque, Guillem, Moussaoui, Mohammed, Becknell, Brian, Boix, Ester

“…Human Ribonuclease (RNase) 6 is a monocyte and macrophage-derived protein with potent antimicrobial activity toward uropathogenic bacteria. The gene is…”
Get full text

Connecting peptide physicochemical and antimicrobial properties by a rational prediction model by Torrent, Marc, Andreu, David, Nogués, Victòria M, Boix, Ester

“…The increasing rate in antibiotic-resistant bacterial strains has become an imperative health issue. Thus, pharmaceutical industries have focussed their…”
Get full text

Editorial: Role of Ribonucleases in Immune Response Regulation During Infection and Cancer by Boix, Ester, Acquati, Francesco, Leonidas, Demetres, Pulido, David

Get full text

Rationally Modified Antimicrobial Peptides from the N‑Terminal Domain of Human RNase 3 Show Exceptional Serum Stability by Sandín, Daniel, Valle, Javier, Chaves-Arquero, Belén, Prats-Ejarque, Guillem, Larrosa, María Nieves, González-López, Juan José, Jiménez, María Ángeles, Boix, Ester, Andreu, David, Torrent, Marc

“…Multidrug resistance against conventional antibiotics poses an important threat to human health. In this context, antimicrobial peptides (AMPs) have been…”
Get full text

AMPA: an automated web server for prediction of protein antimicrobial regions by Torrent, Marc, Di Tommaso, Paolo, Pulido, David, Nogués, M. Victòria, Notredame, Cedric, Boix, Ester, Andreu, David

“…AMPA is a web application for assessing the antimicrobial domains of proteins, with a focus on the design on new antimicrobial drugs. The application provides…”
Get full text

Exploring new biological functions of amyloids: bacteria cell agglutination mediated by host protein aggregation by Torrent, Marc, Pulido, David, Nogués, M Victòria, Boix, Ester

“…Antimicrobial proteins and peptides (AMPs) are important effectors of the innate immune system that play a vital role in the prevention of infections. Recent…”
Get full text

Two Human Host Defense Ribonucleases against Mycobacteria, the Eosinophil Cationic Protein (RNase 3) and RNase 7 by PULIDO, David, TORRENT, Marc, ANDREU, David, NOGUES, M. Victoria, BOIX, Ester

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Human Antimicrobial RNases Inhibit Intracellular Bacterial Growth and Induce Autophagy in Mycobacteria-Infected Macrophages by Lu, Lu, Arranz-Trullén, Javier, Prats-Ejarque, Guillem, Pulido, David, Bhakta, Sanjib, Boix, Ester

“…The development of novel treatment against tuberculosis is a priority global health challenge. Antimicrobial proteins and peptides offer a multifaceted…”
Get full text

Insights into the Antimicrobial Mechanism of Action of Human RNase6: Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation by Pulido, David, Arranz-Trullén, Javier, Prats-Ejarque, Guillem, Velázquez, Diego, Torrent, Marc, Moussaoui, Mohammed, Boix, Ester

“…Human Ribonuclease 6 is a secreted protein belonging to the ribonuclease A (RNaseA) superfamily, a vertebrate specific family suggested to arise with an…”
Get full text

Evolutionary Trends in RNA Base Selectivity Within the RNase A Superfamily by Prats-Ejarque, Guillem, Lu, Lu, Salazar, Vivian A., Moussaoui, Mohammed, Boix, Ester

“…There is a growing interest in the pharmaceutical industry to design novel tailored drugs for RNA targeting. The vertebrate-specific RNase A superfamily is…”
Get full text

Structure-Based Design of an RNase Chimera for Antimicrobial Therapy by Prats-Ejarque, Guillem, Lorente, Helena, Villalba, Clara, Anguita, Raúl, Lu, Lu, Vázquez-Monteagudo, Sergi, Fernández-Millán, Pablo, Boix, Ester

“…Bacterial resistance to antibiotics urges the development of alternative therapies. Based on the structure-function of antimicrobial members of the RNase A…”
Get full text

Unveiling the Multifaceted Mechanisms of Antibacterial Activity of Buforin II and Frenatin 2.3S Peptides from Skin Micro-Organs of the Orinoco Lime Treefrog ( Sphaenorhynchus lacteus ) by Muñoz-Camargo, Carolina, Salazar, Vivian A, Barrero-Guevara, Laura, Camargo, Sandra, Mosquera, Angela, Groot, Helena, Boix, Ester

“…Amphibian skin is a rich source of natural compounds with diverse antimicrobial and immune defense properties. Our previous studies showed that the frog skin…”
Get full text

Testing a Human Antimicrobial RNase Chimera Against Bacterial Resistance by Prats-Ejarque, Guillem, Li, Jiarui, Ait-Ichou, Fatima, Lorente, Helena, Boix, Ester

“…The emergence of bacterial resistance to the most commonly used antibiotics encourages the design of novel antimicrobial drugs. Antimicrobial proteins and…”
Get full text

Antimicrobial Action and Cell Agglutination by the Eosinophil Cationic Protein Are Modulated by the Cell Wall Lipopolysaccharide Structure by PULIDO, David, MOUSSAOUI, Mohammed, ANDREU, David, NOGUES, M. Victòria, TORRENT, Marc, BOIX, Ester

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text