Search Results - "Boitet, Evan R."
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Inhaled high molecular weight hyaluronan ameliorates respiratory failure in acute COPD exacerbation: a pilot study
Published in Respiratory research (01-02-2021)“…Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) carry significant morbidity and mortality. AECOPD treatment remains limited. High…”
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Novel Therapy of Bicarbonate, Glutathione, and Ascorbic Acid Improves Cystic Fibrosis Mucus Transport
Published in American journal of respiratory cell and molecular biology (01-09-2020)“…Defective airway mucus clearance is a defining characteristic of cystic fibrosis lung disease, and improvements to current mucolytic strategies are needed…”
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Novel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation Phenotypes
Published in PloS one (25-05-2016)“…Tyrosinase is a key enzyme in melanin biosynthesis. Mutations in the gene encoding tyrosinase (Tyr) cause oculocutaneous albinism (OCA1) in humans. Alleles of…”
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NUDC is critical for rod photoreceptor function, maintenance, and survival
Published in The FASEB journal (15-03-2024)“…NUDC (nuclear distribution protein C) is a mitotic protein involved in nuclear migration and cytokinesis across species. Considered a cytoplasmic dynein…”
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NudC regulates photoreceptor disk morphogenesis and rhodopsin localization
Published in The FASEB journal (01-08-2019)“…ABSTRACT The outer segment (OS) of rod photoreceptors consist of a highly modified primary cilium containing phototransduction machinery necessary for light…”
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Effect of elexacaftor/tezacaftor/ivacaftor on mucus and mucociliary clearance in cystic fibrosis
Published in Journal of cystic fibrosis (01-01-2024)“…•Elexacaftor/tezacaftor/ivacaftor increases sputum hydration in cystic fibrosis.•Elexacaftor/tezacaftor/ivacaftor (E/T/I) markedly improves mucociliary…”
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Nucleotide bound to rab11a controls localization in rod cells but not interaction with rhodopsin
Published in The Journal of neuroscience (05-11-2014)“…Precise vectorial transport of rhodopsin is essential for rod photoreceptor health and function. Mutations that truncate or extend the C terminus of rhodopsin…”
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Mucociliary transport deficiency and disease progression in Syrian hamsters with SARS-CoV-2 infection
Published in JCI insight (10-01-2023)“…Substantial clinical evidence supports the notion that ciliary function in the airways is important in COVID-19 pathogenesis. Although ciliary damage has been…”
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Application of GIS to a Baseline Survey of Vertebrate Roadkills in Baldwin County, Georgia
Published in Southeastern naturalist (Steuben, Me.) (2014)“…Physical attributes, traffic volume, and landscape patterns on a particular road are expected to influence the frequency of vertebrate road fatalities. In this…”
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Cover Image
Published in The FASEB journal (15-03-2024)“…The cover image is based on the Research Article NUDC is critical for rod photoreceptor function, maintenance, and survival by Mary Anne Garner et al.,…”
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Journal Article -
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The Role of nudC in Rod Photoreceptor Cell Maintenance: A New Function for an Old Protein
Published 01-01-2019“…The overall health and maintenance of rod photoreceptors depends on directed vectorial transport of rhodopsin from its synthesis within the inner segment to…”
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Dissertation