Search Results - "Boiteau, Anne Boyer"
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Alzheimer's-related endosome dysfunction in Down syndrome is Aβ-independent but requires APP and is reversed by BACE-1 inhibition
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2010)“…An additional copy of the β-amyloid precursor protein (APP) gene causes early-onset Alzheimer's disease (AD) in trisomy 21 (DS). Endosome dysfunction develops…”
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Focal clusters of peri-synaptic matrix contribute to activity-dependent plasticity and memory in mice
Published in Cell reports (Cambridge) (28-05-2024)“…Recent findings show that effective integration of novel information in the brain requires coordinated processes of homo- and heterosynaptic plasticity. In…”
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Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence
Published in JAMA psychiatry (Chicago, Ill.) (01-08-2019)“…Major depressive disorder (MDD) might involve dopamine (DA) reductions. The DA transporter (DAT) regulates DA clearance and neurotransmission and is sensitive…”
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A peptide fragment of ependymin neurotrophic factor uses protein kinase C and the mitogen-activated protein kinase pathway to activate c-Jun N-terminal kinase and a functional AP-1 containing c-Jun and c-Fos proteins in mouse NB2a cells
Published in Journal of neuroscience research (01-05-2003)“…Ependymin (EPN) is a goldfish brain neurotrophic factor previously shown to function in a variety of cellular events related to long‐term memory formation and…”
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Proteoglycan abnormalities in olfactory epithelium tissue from subjects diagnosed with schizophrenia
Published in Schizophrenia research (01-11-2013)“…Abstract Emerging evidence points to proteoglycan abnormalities in the pathophysiology of schizophrenia (SZ). In particular, markedly abnormal expression of…”
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Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology: Accelerated Endocytosis Promotes Late Endocytic Defects
Published in The American journal of pathology (01-08-2008)“…Endocytic dysfunction is an early pathological change in Alzheimer's disease (AD) and Down's syndrome (DS). Using primary fibroblasts from DS individuals, we…”
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Alzheimer's-related endosome dysfunction in Down syndrome is A[beta]-independent but requires APP and is reversed by BACE-1 inhibition
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2010)“…An additional copy of the β-amyloid precursor protein (APP) gene causes early-onset Alzheimer's disease (AD) in trisomy 21 (DS). Endosome dysfunction develops…”
Get full text
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Alzheimer's-Related Endosóme Dysfunction in down Syndrome Is Aß-Independent but Requires App and Is Reversed by BACE-1 Inhibition
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-2010)“…An additional copy of the ß-amyloid precursor protein (APP) gene causes early-onset Alzheimer's disease (AD) in trisomy 21 (DS). Endosóme dysfunction develops…”
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Dietary fat and cholesterol causes neuronal endosomal abnormalities and basal forebrain cholinergic neurodegeneration in wild-type mice
Published in Alzheimer's & dementia (01-07-2010)Get full text
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Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology
Published in The American journal of pathology (2008)“…Endocytic dysfunction is an early pathological change in Alzheimer's disease (AD) and Down's syndrome (DS). Using primary fibroblasts from DS individuals, we…”
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P2-028: Functional analyses of AD-related endocytic trafficking defects in Down syndrome fibroblasts
Published in Alzheimer's & dementia (01-07-2006)Get full text
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Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2010)“…An additional copy of the beta-amyloid precursor protein (APP) gene causes early-onset Alzheimer's disease (AD) in trisomy 21 (DS). Endosome dysfunction…”
Get full text
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CMX-8933, a peptide fragment of the glycoprotein ependymin, promotes activation of AP-1 transcription factor in mouse neuroblastoma and rat cortical cell cultures
Published in Neuroscience letters (19-10-2001)“…An 8-amino acid peptide fragment (CMX-8933) of Ependymin, a glycoprotein component of the extracellular fluid and cerebrospinal fluid of goldfish brain, was…”
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Neuroprotective effects of a new synthetic peptide, CMX-9236, in in vitro and in vivo models of cerebral ischemia
Published in Brain research (14-02-2003)“…NGF (nerve growth factor) and BDNF (brain-derived neurotrophic factor) are protein molecules (MW 26 and 13.6 kDa, respectively) that are neuroprotective in the…”
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