Search Results - "Boissière‐Michot, Florence"

SPARC in cancer‐associated fibroblasts is an independent poor prognostic factor in non‐metastatic triple‐negative breast cancer and exhibits pro‐tumor activity by Alcaraz, Lindsay B., Mallavialle, Aude, Mollevi, Caroline, Boissière‐Michot, Florence, Mansouri, Hanane, Simony‐Lafontaine, Joelle, Laurent‐Matha, Valérie, Chardès, Thierry, Jacot, William, Turtoi, Andrei, Roger, Pascal, Guiu, Séverine, Liaudet‐Coopman, Emmanuelle

“…Triple‐negative breast cancer (TNBC) is the most aggressive breast cancer subtype and lacks specific targeted therapeutic agents. The current mechanistic…”
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In situ hybridization for the assessment of urokinase plasminogen activator and plasminogen activator inhibitor type‑1 in formalin‑fixed paraffin‑embedded breast cancer specimens by Boissière-Michot, Florence, Mollevi, Caroline, Baecker, Volker, Crapez, Evelyne, Jacot, William

“…Urokinase plasminogen activator (uPA) and its inhibitor, plasminogen activator inhibitor type 1 (PAI‑1), have been reported as prognostic and predictive…”
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Impact of FcγRIIa-FcγRIIIa Polymorphisms and KRAS Mutations on the Clinical Outcome of Patients With Metastatic Colorectal Cancer Treated With Cetuximab Plus Irinotecan by BIBEAU, Frédéric, LOPEZ-CRAPEZ, Evelyne, SABOURIN, Jean-Christophe, BOISSIERE-MICHOT, Florence, DI FIORE, Frédénc, THEZENAS, Simon, YCHOU, Marc, BLANCHARD, France, LAMY, Aude, PENAULT-LLORCA, Frédérique, FREBOURG, Thierry, MICHEL, Pierre

“…Purpose The antiepidermal growth factor receptor antibody cetuximab shows activity in irinotecan-refractory metastatic colorectal cancer (mCRC), mainly in…”
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Phase II study evaluating the association of gemcitabine, trastuzumab and erlotinib as first‐line treatment in patients with metastatic pancreatic adenocarcinoma (GATE 1) by Assenat, Eric, Mineur, Laurent, Mollevi, Caroline, Lopez‐Crapez, Evelyne, Lombard‐Bohas, Catherine, Samalin, Emmanuelle, Portales, Fabienne, Walter, Thomas, Forges, Hélène, Dupuy, Marie, Boissière‐Michot, Florence, Ho‐Pun‐Cheung, Alexandre, Ychou, Marc, Mazard, Thibaut

“…In a previous phase II study (THERAPY), cetuximab and trastuzumab combination, as second‐line after progression with gemcitabine, showed disease stabilization…”
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RIP140 regulates transcription factor HES1 oscillatory expression and mitogenic activity in colon cancer cells by Sfeir, Nour, Kajdan, Marilyn, Jalaguier, Stéphan, Bonnet, Sandrine, Teyssier, Catherine, Pyrdziak, Samuel, Yuan, Rong, Bousquet, Emilie, Maraver, Antonio, Bernex, Florence, Pirot, Nelly, Boissière‐Michot, Florence, Castet‐Nicolas, Audrey, Lapierre, Marion, Cavaillès, Vincent

“…The transcription factor receptor‐interacting protein 140 (RIP140) regulates intestinal homeostasis and tumorigenesis through Wnt signaling. In this study, we…”
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Correlation of the TIGIT-PVR immune checkpoint axis with clinicopathological features in triple-negative breast cancer by Boissière-Michot, Florence, Chateau, Marie-Christine, Thézenas, Simon, Guiu, Séverine, Bobrie, Angélique, Jacot, William

“…T cell immunoreceptor with Ig and ITIM domains (TIGIT) interacts with poliovirus receptor (PVR) to contribute to cancer immune escape. Recently, TIGIT and PVR…”
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Clinicopathological Correlates of γδ T Cell Infiltration in Triple-Negative Breast Cancer by Boissière-Michot, Florence, Chabab, Ghita, Mollevi, Caroline, Guiu, Séverine, Lopez-Crapez, Evelyne, Ramos, Jeanne, Bonnefoy, Nathalie, Lafont, Virginie, Jacot, William

“…The prognostic impact of the different tumor-infiltrating lymphocyte (TIL) subpopulations in solid cancers is still debated. Here, we investigated the…”
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Prognostic Value of CXCR2 in Breast Cancer by Boissière-Michot, Florence, Jacot, William, Fraisse, Julien, Gourgou, Sophie, Timaxian, Colin, Lazennec, Gwendal

“…The tumor microenvironment appears essential in cancer progression and chemokines are mediators of the communication between cancer cells and stromal cells. We…”
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Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples by Ho-Pun-Cheung, Alexandre, Bazin, Hervé, Boissière-Michot, Florence, Mollevi, Caroline, Simony-Lafontaine, Joëlle, Landas, Emeline, Bleuse, Jean-Pierre, Chardès, Thierry, Prost, Jean-François, Pèlegrin, André, Jacot, William, Mathis, Gérard, Lopez-Crapez, Evelyne

“…Background Triple-negative breast cancer (TNBC) has a worse prognosis compared with other breast cancer subtypes, and biomarkers to identify patients at high…”
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TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion by Chevalier, Clément, Collin, Guillaume, Descamps, Simon, Touaitahuata, Heiani, Simon, Valérie, Reymond, Nicolas, Fernandez, Laurent, Milhiet, Pierre-Emmanuel, Georget, Virginie, Urbach, Serge, Lasorsa, Laurence, Orsetti, Béatrice, Boissière-Michot, Florence, Lopez-Crapez, Evelyne, Theillet, Charles, Roche, Serge, Benistant, Christine

“…ERBB2 overexpression in human breast cancer leads to invasive carcinoma but the mechanism is not clearly understood. Here we report that TOM1L1 is co-amplified…”
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Improving the response to oxaliplatin by targeting chemotherapy-induced CLDN1 in resistant metastatic colorectal cancer cells by Cherradi, Sara, Garambois, Véronique, Marines, Johanna, Andrade, Augusto Faria, Fauvre, Alexandra, Morand, Olivia, Fargal, Manon, Mancouri, Ferial, Ayrolles-Torro, Adeline, Vezzo-Vié, Nadia, Jarlier, Marta, Loussaint, Gerald, Huvelle, Steve, Joubert, Nicolas, Mazard, Thibault, Gongora, Céline, Pourquier, Philippe, Boissière-Michot, Florence, Rio, Maguy Del

“…Tumor resistance is a frequent cause of therapy failure and remains a major challenge for the long-term management of colorectal cancer (CRC). The aim of this…”
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Characterization of an adaptive immune response in microsatellite-instable colorectal cancer by Boissière-Michot, Florence, Lazennec, Gwendal, Frugier, Hélène, Jarlier, Marta, Roca, Lise, Duffour, Jacqueline, Du Paty, Emilie, Laune, Daniel, Blanchard, France, Le Pessot, Florence, Sabourin, Jean-Christophe, Bibeau, Frédéric

“…Sporadic or hereditary colorectal cancer (CRC) with microsatellite instability (MSI) is frequently characterized by inflammatory lymphocytic infiltration and…”
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PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody by They, Laetitia, Michaud, Henri-Alexandre, Becquart, Ondine, Lafont, Virginie, Guillot, Bernard, Boissière-Michot, Florence, Jarlier, Marta, Mollevi, Caroline, Eliaou, Jean-François, Bonnefoy, Nathalie, Gros, Laurent

“…Tumor antigen-targeting monoclonal antibodies (TA-targeting mAbs) are used as therapeutics in many malignancies and their capacity to mobilize the host…”
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EGFR and HER3 mRNA expression levels predict distant metastases in locally advanced rectal cancer by Ho‐Pun‐Cheung, Alexandre, Assenat, Eric, Bascoul‐Mollevi, Caroline, Bibeau, Frédéric, Boissière‐Michot, Florence, Cellier, Dominic, Azria, David, Rouanet, Philippe, Senesse, Pierre, Ychou, Marc, Lopez‐Crapez, Evelyne

“…Aberrant activation of the HER signaling pathways plays a critical role in the invasive and metastatic potential of tumors. The aim of this study was to…”
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Reproductive Decision-Making in MMR Mutation Carriers After Results Disclosure: Impact of Psychological Status in Childbearing Options by Duffour, Jacqueline, Combes, Audrey, Crapez, Evelyne, Boissière-Michot, Florence, Bibeau, Frédéric, Senesse, Pierre, Ychou, Marc, Courraud, Julie, de Forges, Hélène, Roca, Lise

“…Reproductive techniques such as prenatal diagnosis (PND) or preimplantation genetic diagnosis (PGD), although debated, are legally forbidden in France in case…”
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Prognostic Value of HER2-Low Expression in Non-Metastatic Triple-Negative Breast Cancer and Correlation with Other Biomarkers by Jacot, William, Maran-Gonzalez, Aurélie, Massol, Océane, Sorbs, Charlotte, Mollevi, Caroline, Guiu, Séverine, Boissière-Michot, Florence, Ramos, Jeanne

“…HER2-low breast cancer (i.e., HER 1+ or 2+, without gene amplification) is an emerging subtype for which very few data are available, especially within the…”
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CXCR2 Levels Correlate with Immune Infiltration and a Better Prognosis of Triple-Negative Breast Cancers by Boissière-Michot, Florence, Jacot, William, Massol, Océane, Mollevi, Caroline, Lazennec, Gwendal

“…Chemokines and their receptors are key players in breast cancer progression and outcome. Previous studies have shown that the chemokine receptor CXCR2 was…”
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Reverse transcription-quantitative polymerase chain reaction: description of a RIN-based algorithm for accurate data normalization by Ho-Pun-Cheung, Alexandre, Bascoul-Mollevi, Caroline, Assenat, Eric, Boissière-Michot, Florence, Bibeau, Frédéric, Cellier, Dominic, Ychou, Marc, Lopez-Crapez, Evelyne

“…Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) is the gold standard technique for mRNA quantification, but appropriate normalization is…”
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Immune and Gene-expression Profiling in Estrogen Receptor Low and Negative Early Breast Cancer by Massa, Davide, Vernieri, Claudio, Nicolè, Lorenzo, Criscitiello, Carmen, Boissière-Michot, Florence, Guiu, Séverine, Bobrie, Angélique, Griguolo, Gaia, Miglietta, Federica, Vingiani, Andrea, Lobefaro, Riccardo, Taurelli Salimbeni, Beatrice, Pinato, Claudia, Schiavi, Francesca, Brich, Silvia, Pescia, Carlo, Fusco, Nicola, Pruneri, Giancarlo, Fassan, Matteo, Curigliano, Giuseppe, Guarneri, Valentina, Jacot, William, Dieci, Maria Vittoria

“…The cut-off of < 1% positive cells to define estrogen receptor (ER) negativity by immunohistochemistry (IHC) in breast cancer (BC) is debated. We explored the…”
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Association of CD206 Protein Expression with Immune Infiltration and Prognosis in Patients with Triple-Negative Breast Cancer by Bobrie, Angélique, Massol, Océane, Ramos, Jeanne, Mollevi, Caroline, Lopez-Crapez, Evelyne, Bonnefoy, Nathalie, Boissière-Michot, Florence, Jacot, William

“…Background: Triple-negative breast cancers (TNBCs) have a worse prognosis, but might respond to immunotherapies. Macrophages are plastic cells that can adopt…”
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