Search Results - "Boirivant, Monica"

Anti-CXCL4 Antibody Reactivity Is Present in Systemic Sclerosis (SSc) and Correlates with the SSc Type I Interferon Signature by Lande, Roberto, Mennella, Anna, Palazzo, Raffaella, Pietraforte, Immacolata, Stefanantoni, Katia, Iannace, Nicoletta, Butera, Alessia, Boirivant, Monica, Pica, Roberta, Conrad, Curdin, Chizzolini, Carlo, Riccieri, Valeria, Frasca, Loredana

“…Systemic sclerosis (SSc) is characterized by skin/internal organ fibrosis, vasculopathy and autoimmunity. Chemokine (C-X-C motif) ligand 4 (CXCL4) is an SSc…”
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Regulation of Gut Inflammation and Th17 Cell Response by Interleukin-21 by Fina, Daniele, Sarra, Massimiliano, Fantini, Massimo C, Rizzo, Angelamaria, Caruso, Roberta, Caprioli, Flavio, Stolfi, Carmine, Cardolini, Iris, Dottori, Marta, Boirivant, Monica, Pallone, Francesco, MacDonald, Thomas T, Monteleone, Giovanni

“…Background & Aims: Interleukin (IL)-21, a T-cell-derived cytokine, is overproduced in inflammatory bowel diseases (IBD), but its role in the pathogenesis of…”
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CD3+CD4+LAP+Foxp3-Regulatory Cells of the Colonic Lamina Propria Limit Disease Extension in Ulcerative Colitis by Butera, Alessia, Sanchez, Massimo, Pronio, Annamaria, Amendola, Antonello, De Nitto, Daniela, Di Carlo, Nazzareno, Lande, Roberto, Frasca, Loredana, Borrini, Francesco, Pica, Roberta, Boirivant, Monica

“…In ulcerative colitis (UC), inflammation begins in the rectum and can extend proximally throughout the entire colon. The extension of inflammation is an…”
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Endoluminal calprotectin measurement in assessment of pouchitis and a new index of disease activity: a pilot study by Pronio, Annamaria, Di Filippo, Annalisa R, Mariani, Paola, Vestri, Annarita, Montesani, Chiara, Boirivant, Monica

“…Pouchitis is the most common complication following proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis (UC). To provide a standardized…”
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The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis by Casorelli, Ida, Pannellini, Tania, De Luca, Gabriele, Degan, Paolo, Chiera, Federica, Iavarone, Ivano, Giuliani, Alessandro, Butera, Alessia, Boirivant, Monica, Musiani, Piero, Bignami, Margherita

“…The Mutyh DNA glycosylase is involved in the repair of oxidized DNA bases. Mutations in the human MUTYH gene are responsible for colorectal cancer in familial…”
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Cholera toxin B subunit promotes the induction of regulatory T cells by preventing human dendritic cell maturation by D'Ambrosio, Antonella, Colucci, Manuela, Pugliese, Orsola, Quintieri, Francesca, Boirivant, Monica

“…Cholera toxin B subunit (CTB) is an efficient mucosal carrier molecule for the generation of immune responses to linked antigens. There is also good evidence…”
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Oral sensitization with shrimp tropomyosin induces in mice allergen-specific IgE, T cell response and systemic anaphylactic reactions by Capobianco, Francescamaria, Butteroni, Cinzia, Barletta, Bianca, Corinti, Silvia, Afferni, Claudia, Tinghino, Raffaella, Boirivant, Monica, Di Felice, Gabriella

“…Appropriate murine models of shrimp tropomyosin (ST) allergy would be useful in investigating the mechanisms underlying food allergy in human subjects, as well…”
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The mechanism of action of probiotics by Boirivant, Monica, Strober, Warren

“…PURPOSE OF REVIEWProbiotics are a heterogeneous group of nonpathologic bacteria that are functionally defined by their ability to allay inflammation when…”
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CD147 Targeting by AC-73 Induces Autophagy and Reduces Intestinal Fibrosis Associated with TNBS Chronic Colitis by Butera, Alessia, Quaranta, Maria Teresa, Crippa, Luca, Spinello, Isabella, Saulle, Ernestina, Di Carlo, Nazzareno, Campanile, Doriana, Boirivant, Monica, Labbaye, Catherine

“…Abstract Background and Aims Intestinal fibrosis is a common complication of inflammatory bowel diseases. Medical treatment of intestinal fibrosis is an unmet…”
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Beneficial Effects of Fingolimod on Social Interaction, CNS and Peripheral Immune Response in the BTBR Mouse Model of Autism by De Simone, Roberta, Butera, Alessia, Armida, Monica, Pezzola, Antonella, Boirivant, Monica, Potenza, Rosa Luisa, Ricceri, Laura

“…•Fingolimod (FTY720) improves social responsiveness in BTBR male mice, a mouse model of autism spectrum disorder.•FTY720 normalizes hippocampal BDNF mRNA…”
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Effects of a gut-selective integrin-targeted therapy in male mice exposed to early immune activation, a model for the study of autism spectrum disorder by Butera, Alessia, De Simone, Roberta, Potenza, Rosa Luisa, Sanchez, Massimo, Armida, Monica, Campanile, Doriana, Di Carlo, Nazzareno, Trenta, Francesco, Boirivant, Monica, Ricceri, Laura

“…•Gut immune-mediated inflammation is present in ASD mouse models.•Abrogation of gut inflammation rescues social novelty deficit and specific neuroinflammatory…”
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Probiotics ameliorate recurrent Th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells by Di Giacinto, Claudia, Marinaro, Mariarosaria, Sanchez, Massimo, Strober, Warren, Boirivant, Monica

“…Recent studies of murine models of mucosal inflammation suggest that, whereas some kinds of bacterial microflora are inducers of disease, others, known as…”
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Human intestinal lamina propria lymphocytes are naturally permissive to HIV-1 infection by Lapenta, Caterina, Boirivant, Monica, Marini, Marco, Santini, Stefano M., Logozzi, Mariantonia, Viora, Marina, Belardelli, Filippo, Fais, Stefano

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IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes by Peluso, Ilaria, Fantini, Massimo Claudio, Fina, Daniele, Caruso, Roberta, Boirivant, Monica, MacDonald, Thomas T, Pallone, Francesco, Monteleone, Giovanni

“…High expression of IL-21 and/or IL-21R has been described in T cell-mediated inflammatory diseases characterized by defects of counterregulatory mechanisms…”
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Probiotic administration in patients with ileal pouch–anal anastomosis for ulcerative colitis is associated with expansion of mucosal regulatory cells by Pronio, Annamaria, Montesani, Chiara, Butteroni, Cinzia, Vecchione, Simona, Mumolo, Gloria, Vestri, AnnaRita, Vitolo, Domenico, Boirivant, Monica

“…Background: Probiotics have anti‐inflammatory effects in patients with inflammatory bowel disease and appear to regulate mucosal immune response through…”
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IL-13 mRNA Tissue Content Identifies Two Subsets of Adult Ulcerative Colitis Patients With Different Clinical and Mucosa-Associated Microbiota Profiles by Butera, Alessia, Di Paola, Monica, Vitali, Francesco, De Nitto, Daniela, Covotta, Francesco, Borrini, Francesco, Pica, Roberta, De Filippo, Carlotta, Cavalieri, Duccio, Giuliani, Alessandro, Pronio, Annamaria, Boirivant, Monica

“…Abstract Background and Aims A personalized approach to therapy hold great promise to improve disease outcomes. To this end, the identification of different…”
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Tu1781 - Stratification of Ulcerative Colitis Patients According to Distinctive Tissue Cytokine Profiles by Butera, Alessia, De Nitto, Daniela, Ciamberlano, Bernardo, Giuliani, Alessandro, Pica, Roberta, Pronio, Annamaria, Boirivant, Monica

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Probiotic VSL#3-induced TGF-β ameliorates food allergy inflammation in a mouse model of peanut sensitization through the induction of regulatory T cells in the gut mucosa by Barletta, Bianca, Rossi, Giacomo, Schiavi, Elisa, Butteroni, Cinzia, Corinti, Silvia, Boirivant, Monica, Di Felice, Gabriella

“…Scope Among food allergies, peanut allergy is frequently associated with severe anaphylactic reactions. In the need for safe and effective therapeutic…”
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Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis by Fuss, Ivan J, Heller, Frank, Boirivant, Monica, Leon, Francisco, Yoshida, Masaru, Fichtner-Feigl, Stefan, Yang, Zhiqiong, Exley, Mark, Kitani, Atsushi, Blumberg, Richard S, Mannon, Peter, Strober, Warren

“…While Crohn disease (CD) has been clearly identified as a Th1 inflammation, the immunopathogenesis of its counterpart inflammatory bowel disease, ulcerative…”
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Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis by Fuss, Ivan J., Heller, Frank, Boirivant, Monica, Leon, Francisco, Yoshida, Masaru, Fichtner-Feigl, Stefan, Yang, Zhiqiong, Exley, Mark, Kitani, Atsushi, Blumberg, Richard S., Mannon, Peter, Strober, Warren

“…While Crohn disease (CD) has been clearly identified as a Th1 inflammation, the immunopathogenesis of its counterpart inflammatory bowel disease, ulcerative…”
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