Search Results - "Boiko, Julie R"

Hematopoiesis sculpted by pathogens: Toll-like receptors and inflammatory mediators directly activate stem cells by Boiko, Julie R., Borghesi, Lisa

“…► Hematopoietic stem cells (HSCs) functionally respond to Toll-like receptor (TLR) ligation. ► TLR ligation of HSCs alters self-renewal and differentiation…”
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Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation by Yeh, Albert C, Koyama, Motoko, Waltner, Olivia G, Minnie, Simone A, Boiko, Julie R, Shabaneh, Tamer B, Takahashi, Shuichiro, Zhang, Ping, Ensbey, Kathleen S, Schmidt, Christine R, Legg, Samuel R W, Sekiguchi, Tomoko, Nelson, Ethan, Bhise, Shruti S, Stevens, Andrew R, Goodpaster, Tracy, Chakka, Saranya, Furlan, Scott N, Markey, Kate A, Bleakley, Marie E, Elson, Charles O, Bradley, Philip H, Hill, Geoffrey R

“…Allogeneic T cell expansion is the primary determinant of graft-versus-host disease (GVHD), and current dogma dictates that this is driven by…”
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Care Coordination in a SARS-CoV-2-infected Child With Newly Diagnosed Medulloblastoma and Fanconi Anemia by Field, Mary T., Chapple, Alayne, Hoeppner, Corrine, Boiko, Julie R., Tellinghuisen, Amy, Joshi, Sarita, Vitanza, Nicholas A.

“…COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is responsible for a global pandemic that can cause severe infections in…”
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Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD by Wang, Yewei, Ullah, Md Ashik, Waltner, Olivia G, Bhise, Shruti S, Ensbey, Kathleen S, Schmidt, Christine R, Legg, Samuel Rw, Sekiguchi, Tomoko, Nelson, Ethan L, Kuns, Rachel D, Nemychenkov, Nicole S, Atilla, Erden, Yeh, Albert C, Takahashi, Shuichiro, Boiko, Julie R, Varelias, Antiopi, Blazar, Bruce R, Koyama, Motoko, Minnie, Simone A, Clouston, Andrew D, Furlan, Scott N, Zhang, Ping, Hill, Geoffrey R

“…Calcineurin inhibitors (CNIs) constitute the backbone of modern acute graft-versus-host disease (aGVHD) prophylaxis regimens but have limited efficacy in the…”
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TIM-3 + CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies by Minnie, Simone A, Waltner, Olivia G, Zhang, Ping, Takahashi, Shuichiro, Nemychenkov, Nicole S, Ensbey, Kathleen S, Schmidt, Christine R, Legg, Samuel R W, Comstock, Melissa, Boiko, Julie R, Nelson, Ethan, Bhise, Shruti S, Wilkens, Alec B, Koyama, Motoko, Dhodapkar, Madhav V, Chesi, Marta, Riddell, Stanley R, Green, Damian J, Spencer, Andrew, Furlan, Scott N, Hill, Geoffrey R

“…Chronic antigen stimulation is thought to generate dysfunctional CD8 T cells. Here, we identify a CD8 T cell subset in the bone marrow tumor microenvironment…”
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Portomesenteric Venous Thrombosis in Previously Healthy Adolescents Presenting With Subacute Abdominal Pain by Boiko, Julie R., Srinath, Arvind I., Cooper, James D.

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Regulatory T Cells Display Increased Memory Phenotype Following Allogeneic Hematopoietic Cell Transplantation by Boiko, Julie R., MS, Im, Annie, MD, Chen, Xiaohua, MD, PhD, Hill, Memphis J., BS, Szabolcs, Paul, MD

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Portomesenteric Venous Thrombosis As First Presentation of Thrombophilic Disorders in Adolescents by Boiko, Julie R., Cooper, James D.

“…Introduction Portomesenteric venous thrombosis is rare in children and adolescents. Rapid recognition of this uncommon phenomenon is essential to prevent…”
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Type-1 regulatory T cells are critical for curative immunotherapy outcomes by Zhang, ping, Gartlan, Kate H, Minnie, Simone A, Yeh, Albert, Takahashi, Shuichiro, Atilla, Erden, Nemychenkov, Nicole S, Boiko, Julie R, Schmidt, Christine R, Legg, Samuel RW, Sekiguchi, Tomoko, Ensbey, Kathleen S, Koyama, Motoko, Furlan, Scott N, Hill, Geoffrey R

“…Abstract IL-10 producing CD4 +type-1 regulatory T cells (Tr1) mediate immune tolerance during chronic infection, autoimmunity, and transplantation. We…”
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Characterization of Regulatory T Cell Reconstitution after Allogeneic Hematopoietic Cell Transplantation: Expansion Potential at 100 Days Predicts De Novo Graft-Versus-Host Disease By Six Months Post-Transplantation by Boiko, Julie R., Im, Annie, Chen, Xiaohua, Hill, Memphis J, Szabolcs, Paul

“…Introduction Regulatory T cells (CD4+CD25high CD127low Foxp3+) (Tregs) are of increasing interest in the context of allogeneic hematopoietic cell…”
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Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease by Boiko, Julie R, Ensbey, Kathleen S, Schmidt, Christine R, Waltner, Olivia G, Minnie, Simone A, Furlan, Scott N, Hill, Geoffrey R

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320 - Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease by Boiko, Julie R, Ensbey, Kathleen S, Schmidt, Christine R, Waltner, Olivia G, Minnie, Simone A, Furlan, Scott N, Hill, Geoffrey R

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333 - Decline in Chronic Gvhd (cGVHD) at Fred Hutchinson Cancer Center (FHCC) between 2005 and 2019 by Carpenter, Paul A., Gooley, Ted A., Boiko, Julie R, Rashid, Nahid, Yeh, Albert, Vo, Phuong, Oshima, Masumi Ueda, Salit, Rachel B., Krakow, Elizabeth F., Flowers, Mary E.D., Burroughs, Lauri M., Bhatt, Neel S., Summers, Corinne, Lee, Stephanie J

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Decline in Chronic Gvhd (cGVHD) at Fred Hutchinson Cancer Center (FHCC) between 2005 and 2019 by Carpenter, Paul A., Gooley, Ted A., Boiko, Julie R, Rashid, Nahid, Yeh, Albert, Vo, Phuong, Oshima, Masumi Ueda, Salit, Rachel B., Krakow, Elizabeth F., Flowers, Mary E.D., Burroughs, Lauri M., Bhatt, Neel S., Summers, Corinne, Lee, Stephanie J

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Decreasing chronic graft-versus-host disease rates in all populations by Carpenter, Paul A., Gooley, Ted A., Boiko, Julie, Lee, Catherine J., Burroughs, Lauri M., Mehta, Rohtesh, Salit, Rachel B., Bhatt, Neel S., Krakow, Elizabeth, Dahlberg, Ann E., Yeh, Albert C., Summers, Corinne N., Ueda Oshima, Masumi, Petersdorf, Effie W., Vo, Phuong, Connelly-Smith, Laura, Lee, Stephanie J.

“…•cGVHD declined by ∼19% with each 5-year increment in HCT date even after adjusting for the typically expected cause-associated factors.•cGVHD declines were…”
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IgG Allotypes Reveal That Antimicrobial Humoral Immunity Persists after Reduced-Intensity Hematopoietic Cell Transplantation by Boiko, Julie R., Sahaf, Bita, Mueller, Antonia M.S., Chen, George L., Tyan, Dolly, Miklos, David B.

“…Allogeneic hematopoietic cell transplantation (HCT) is an effective treatment for hematologic malignancies through graft-versus-leukemia/lymphoma (GVL)…”
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Rituximab Infusion Two Months after HCT Decreases Alloreactive B Cell Responses While Recipient Plasma Cells Persist by Sahaf, Bi ta, Boiko, Julie R., Chen, George, Heydari, Kartoosh, Arai, Sally, Miklos, David

“…B cells and their effector molecules, antibodies, are implicated in pathophysiology of the chronic graft-vs-host disease (cGVHD) and rituximab is effective…”
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Allotype Reagents Distinguish Donor and Recipient Antibodies after Hematopoietic Transplantation by Boiko, Julie R., Sahaf, Bita, Miklos, David B.

“…Allogeneic immune responses provide beneficial graft-versus-leukemia (GVL) and detrimental graft-versus-host disease (GVHD). To characterize allogeneic B cells…”
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