Search Results - "Bohning, Kelly"
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Single dose of chimeric dengue-2/Zika vaccine candidate protects mice and non-human primates against Zika virus
Published in Nature communications (16-12-2021)“…The development of a safe and effective Zika virus (ZIKV) vaccine has become a global health priority since the widespread epidemic in 2015-2016. Based on…”
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A high throughput reporter virus particle microneutralization assay for quantitation of Zika virus neutralizing antibodies in multiple species
Published in PloS one (23-04-2021)“…Zika virus is a Flavivirus, transmitted via Aedes mosquitos, that causes a range of symptoms including Zika congenital syndrome. Zika has posed a challenging…”
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Complete Protection in Macaques Conferred by Purified Inactivated Zika Vaccine: Defining a Correlate of Protection
Published in Scientific reports (26-02-2020)“…A critical global health need exists for a Zika vaccine capable of mitigating the effects of future Zika epidemics. In this study we evaluated the antibody…”
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Purified Inactivated Zika Vaccine Candidates Afford Protection against Lethal Challenge in Mice
Published in Scientific reports (07-11-2018)“…In response to the 2016 global public health emergency of international concern announced by the World Health Organization surrounding Zika virus (ZIKV)…”
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Specificity and Breadth of the Neutralizing Antibody Response to a Live-Attenuated Tetravalent Dengue Vaccine
Published in The Journal of infectious diseases (28-11-2022)“…An effective dengue vaccine should ideally induce broadly neutralizing antibody (nAb) responses against all 4 dengue virus (DENV) serotypes. We characterized…”
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Persistence of Immunogenicity of a Purified Inactivated Zika Virus Vaccine Candidate in Healthy Adults: 2 Years of Follow-up Compared With Natural Infection
Published in The Journal of infectious diseases (29-05-2023)“…Abstract Background We report 2-year persistence of immune response to Takeda's prophylactic purified formalin-inactivated whole Zika virus vaccine candidate…”
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