Search Results - "Bohme, G"
-
1
The grapefruit polyphenol naringenin inhibits multiple cardiac ion channels
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-06-2022)“…Drinking fresh grapefruit juice is associated with a significant prolongation of the QT segment on the electrocardiogram (ECG) in healthy volunteers. Among the…”
Get full text
Journal Article -
2
The atypic antipsychotic clozapine inhibits multiple cardiac ion channels
Published in Naunyn-Schmiedeberg's archives of pharmacology (2023)“…Clozapine is an atypical neuroleptic used to manage treatment-resistant schizophrenia which is known to inhibit cardiac hERG/K V 11.1 potassium channels, a…”
Get full text
Journal Article -
3
Moment-closure approximations for discrete adaptive networks
Published in Physica. D (2014)“…Moment-closure approximations are an important tool in the analysis of the dynamics on both static and adaptive networks. Here, we provide a broad survey over…”
Get full text
Journal Article -
4
Automated Patch-Clamp Methods for the hERG Cardiac Potassium Channel
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…The human Ether-a-go-go Related Gene (hERG) product has been identified as a central ion channel underlying both familial forms of elongated QT interval on the…”
Get more information
Journal Article -
5
In vitro ion channel profile and ex vivo cardiac electrophysiology properties of the R(-) and S(+) enantiomers of hydroxychloroquine
Published in European journal of pharmacology (15-01-2022)“…Hydroxychloroquine (HCQ) is a derivative of the antimalaria drug chloroquine primarily prescribed for autoimmune diseases. Recent attempts to repurpose HCQ in…”
Get full text
Journal Article -
6
Electrophysiological and Pharmacological Characterization of Human Inwardly Rectifying K ir 2.1 Channels on an Automated Patch-Clamp Platform
Published in Assay and drug development technologies (01-04-2019)“…Inwardly rectifying I potassium currents of the heart control the resting membrane potential of ventricular cardiomyocytes during diastole and contribute to…”
Get more information
Journal Article -
7
Enhanced long-term potentiation in mice lacking cannabinoid CB1 receptors
Published in Neuroscience (2000)“…Marijuana is known to affect learning and memory in humans, and cannabinoids block long-term potentiation in the hippocampus, a model for the synaptic changes…”
Get full text
Journal Article -
8
Enhancement of memory in cannabinoid CB1 receptor knock-out mice
Published in European journal of pharmacology (20-08-1999)“…We have used cannabinoid CB knock-out mice in a two-trial object recognition test to assess the role of cannabinoid CB receptors in memory. Cannabinoid CB1…”
Get full text
Journal Article -
9
Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
Published in Human molecular genetics (15-09-2003)“…Mutations of the parkin gene are the most frequent cause of early onset autosomal recessive parkinsonism (EO-AR). Here we show that inactivation of the parkin…”
Get full text
Journal Article -
10
1400W, a potent selective inducible NOS inhibitor, improves histopathological outcome following traumatic brain injury in rats
Published in Nitric oxide (01-03-2005)“…There are conflicting data regarding the role of nitric oxide (NO) produced by inducible NO synthase (iNOS) in the pathophysiology of traumatic brain injury…”
Get full text
Journal Article -
11
Nonlinear phenomena in the natural howling of a dog-wolf mix
Published in The Journal of the Acoustical Society of America (01-10-2000)“…It was reported to the first author that a female dog-wolf mix showed anomalously rough-sounding vocalization. Spectral analysis of recordings of the…”
Get full text
Journal Article -
12
Enterococcus faecium strains with vanA-mediated high-level glycopeptide resistance isolated from animal foodstuffs and fecal samples of humans in the community
Published in Microbial drug resistance (Larchmont, N.Y.) (1995)“…The occurrence and the further spread of high-level glycopeptide-resistant, vanA-positive Enterococcus faecium strains outside of hospitals have been…”
Get more information
Journal Article -
13
A Wide Variety of Mutations in the Parkin Gene Are Responsible for Autosomal Recessive Parkinsonism in Europe
Published in Human molecular genetics (01-04-1999)“…Autosomal recessive juvenile parkinsonism (AR-JP, PARK2; OMIM 602544), one of the monogenic forms of Parkinson's disease (PD), was initially described in…”
Get full text
Journal Article -
14
Analysis of non-Newtonian effects in peristaltic pumping
Published in Journal of non-Newtonian fluid mechanics (01-11-2013)“…•We analyze the fluid transport by means of long traveling waves analytically.•Negative free pumping may occur with shear thinning fluids at particular wave…”
Get full text
Journal Article -
15
Quinupristin/dalfopristin-resistant enterococci of the satA (vatD) and satG (vatE) genotypes from different ecological origins in Germany
Published in Microbial drug resistance (Larchmont, N.Y.) (2000)“…The semisynthetic streptogramin combination quinupristin/dalfopristin (Synercid) is a promising alternative for treatment of infections due to multiply…”
Get more information
Journal Article -
16
Propulsion of axisymmetric swimmers in viscoelastic liquids by means of torsional oscillations
Published in Journal of non-Newtonian fluid mechanics (01-10-2015)“…•Swimmers in polymeric liquids can be propelled utilizing the fluid elasticity.•Torsional oscillations are appropriate actions producing propelling forces.•An…”
Get full text
Journal Article -
17
Cloning of Rat Parkin cDNA and Distribution of Parkin in Rat Brain
Published in Journal of neurochemistry (01-04-2000)“…: The rat parkin cDNA sequence was characterized after screening a rat hypothalamus cDNA library with a 32P‐labeled probe containing the entire open reading…”
Get full text
Journal Article -
18
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
Published in Science (American Association for the Advancement of Science) (15-01-1999)“…The function of the central cannabinoid receptor (CB1) was investigated by invalidating its gene. Mutant mice did not respond to cannabinoid drugs,…”
Get full text
Journal Article -
19
A dynamic approach to identifying desired physiological phases for cardiac imaging using multislice spiral CT
Published in Medical physics (Lancaster) (01-07-2003)“…In this investigation, we describe a quantitative technique to measure coronary motion, which can be correlated with cardiac image quality using multislice…”
Get full text
Journal Article -
20
Voice profiles and standard voice profile of untrained children
Published in Journal of voice (01-09-1995)“…Voice profiles were taken of 277 healthy children between the ages of 5 and 14 years. The measured phonetograms were grouped according to sex and years of age…”
Get full text
Journal Article